@incollection{,
	
					
					
					E452DBA35518E74B52431F79969092ED
					,
	note={Type: Double Blind Peer Reviewed International Research Journal Publisher: Global Journals Inc. (USA)}
				,
	author={{DavidHydock} and {Colin JQuinn} and {Noah M.Gibson} and {University of Northern Colorado}},
	journal={{Global Journal of Medical Research}},
	journal={{GJMR}}2249-46180975-588810.34257/GJMR,
	address={Cambridge, United States},
	publisher={Global Journals Organisation}1661122
}

@incollection{b0,
	
	
		,
	title={{Doxorubicin cardiotoxicity and the control of iron metabolism: Quinone-dependent and independent mechanisms}}
		,
	author={{
			GMinotti
		} and {
			SRecalcati
		} and {
			PMenna
		} and {
			ESalvatorelli
		} and {
			GCorna
		} and {
			GCairo
		}}
		
		
		
		
		
	
	
		,
	journal={{Methods Enzymol}}
		
			378
			
			,
	year={2004}
		
	

}

@incollection{b1,
	
	
		,
	title={{Doxorubicin-induced apoptosis: Implications in cardiotoxicity}}
		,
	author={{
			BKalyanaraman
		} and {
			JJoseph
		} and {
			SKalivendi
		} and {
			SWang
		} and {
			EKonorev
		} and {
			SKotamraju
		}}
		
		
		
		
		
	
	
		,
	journal={{Molecular and cellular biochemistry}}
		
			
			,
	year={2002}
		
	

}

@incollection{b2,
	
	
		,
	title={{Chronic doxorubicin cardiotoxicity is mediated by oxidative dna damage-atm-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of rac1 activity}}
		,
	author={{
			MYoshida
		} and {
			IShiojima
		} and {
			HIkeda
		} and {
			IKomuro
		}}
		
		
		
	
	
		,
	journal={{Journal of molecular and cellular cardiology}}
		
			47
			
			,
	year={2009}
		
	

}

@incollection{b3,
	
	
		,
	title={{Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats}}
		,
	author={{
			DLebrecht
		} and {
			AGeist
		} and {
			UPKetelsen
		} and {
			JHaberstroh
		} and {
			BSetzer
		} and {
			UAWalker
		}}
		
		
		
		
		
	
	
		,
	journal={{British journal of pharmacology}}
		
			151
			
			,
	year={2007}
		
	

}

@incollection{b4,
	
	
		,
	title={{Doxorubicin-induced markers of myocardial autophagic signaling in sedentary and exercise trained animals}}
		,
	author={{
			AJSmuder
		} and {
			ANKavazis
		} and {
			KMin
		} and {
			SKPowers
		}}
		
		
		
	
	
		,
	journal={{J Appl Physiol}}
		
			115
			
			,
	year={1985. 2013}
		
	

}

@incollection{b5,
	
	
		,
	title={{Autophagy upregulation promotes survival and attenuates doxorubicin-induced cardiotoxicity}}
		,
	author={{
			BJSishi
		} and {
			BLoos
		} and {
			JVan Rooyen
		} and {
			AMEngelbrecht
		}}
		
		
		
	
	
		,
	journal={{Biochemical pharmacology}}
		
			85
			
			,
	year={2013}
		
	

}

@incollection{b6,
	
	
		,
	title={{Exercise as a beneficial adjunct therapy during doxorubicin treatment-role of mitochondria in cardioprotection}}
		,
	author={{
			AAscensão
		} and {
			PJOliveira
		} and {
			JMagalhães
		}}
		
		
	
	
		,
	journal={{International journal of cardiology}}
		
			156
			
			,
	year={2012}
		
	

}

@incollection{b7,
	
	
		,
	title={{Rigorous exercise training increases superoxide dismutase activity in ventricular myocardium}}
		,
	author={{
			SKPowers
		} and {
			DCriswell
		} and {
			JLawler
		} and {
			DMartin
		} and {
			FLieu
		} and {
			LJi
		}}
		
		
		
		
		
	
	
		,
	journal={{American Journal of Physiology-Heart and Circulatory Physiology}}
		
			265
			
			,
	year={1993}
		
	

}

@incollection{b8,
	
	
		,
	title={{Exercise mitigates cardiac doxorubicin accumulation and preserves function in the rat}}
		,
	author={{
			BTJensen
		} and {
			CYLien
		} and {
			DSHydock
		} and {
			CMSchneider
		} and {
			RHayward
		}}
		
		
		
		
	
	
		,
	journal={{Journal of cardiovascular pharmacology}}
		
			62
			
			,
	year={2013}
		
	

}

@incollection{b9,
	
	
		,
	title={{Exercise preconditioning protects against doxorubicin-induced cardiac dysfunction}}
		,
	author={{
			DSHydock
		} and {
			CYLien
		} and {
			CMSchneider
		} and {
			RHayward
		}}
		
		
		
	
	
		,
	journal={{Med Sci Sports Exerc}}
		
			40
			
			,
	year={2008}
		
	

}

@incollection{b10,
	
	
		,
	title={{Exercise preconditioning provides longadenocarcinoma cell lines}}
		,
	author={{
			DSHydock
		} and {
			CYLien
		} and {
			BTJensen
		} and {
			CMSchneider
		} and {
			RHayward
		}}
		
		
		
		
	
	
		,
	journal={{International journal of oncology}}
		
			30
			
			,
	year={2007}
		
	

}

@incollection{b11,
	
	
		,
	title={{Mammalian multidrug-resistance proteins (mrps)}}
		,
	author={{
			AJSlot
		} and {
			SVMolinski
		} and {
			SPCole
		}}
		
		
	
	
		,
	journal={{Essays Biochem}}
		
			50
			
			,
	year={2011}
		
	

}

@incollection{b12,
	
	
		,
	title={{Analysis of the drug resistance profile of multidrug resistance protein 7 (abcc10): Resistance to docetaxel}}
		,
	author={{
			EHopper-Borge
		} and {
			ZSChen
		} and {
			IShchaveleva
		} and {
			MGBelinsky
		} and {
			GDKruh
		}}
		
		
		
		
	
	
		,
	journal={{Cancer research}}
		
			64
			
			,
	year={2004}
		
	

}

@incollection{b13,
	
	
		,
	title={{Mrp1 localization and function in cardiac mitochondria after doxorubicin}}
		,
	author={{
			PJungsuwadee
		} and {
			RNithipongvanitch
		} and {
			YChen
		} and {
			TDOberley
		} and {
			DAButterfield
		} and {
			StClair
		} and {
			DK
		}}
		
		
		
		
		
		
	
	
		,
	journal={{Molecular pharmacology}}
		
			75
			
			,
	year={2009}
		
	

}

@incollection{b14,
	
	
		,
	title={{Exercise training does not affect anthracycline antitumor efficacy while attenuating cardiac dysfunction}}
		,
	author={{
			TLParry
		} and {
			RHayward
		}}
		
	
	
		,
	journal={{Am J Physiol Regul Integr Comp Physiol}}
		
			309
			
			,
	year={2015}
		
	

}

@incollection{b15,
	
	
		,
	title={{Endurance exercise training preserves cardiac function in rats receiving doxorubicin and the her-2 inhibitor gw2974}}
		,
	author={{
			KYWonders
		} and {
			DSHydock
		} and {
			SGreufe
		} and {
			CMSchneider
		} and {
			RHayward
		}}
		
		
		
		
	
	
		,
	journal={{Cancer chemotherapy and pharmacology}}
		
			64
			
			,
	year={2009}
		
	

}

@incollection{b16,
	
	
		,
	title={{Physical exercise prior and during treatment reduces sub-chronic doxorubicin-induced mitochondrial toxicity and oxidative stress}}
		,
	author={{
			IMarques-Aleixo
		} and {
			ESantos-Alves
		} and {
			DMariani
		} and {
			DRizo-Roca
		} and {
			AIPadrão
		} and {
			SRocha-Rodrigues
		}}
		
		
		
		
		
	
	
		,
	journal={{Mitochondrion}}
		
			,
	year={2014}
		
	

}

@incollection{b17,
	
	
		,
	title={{A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding}}
		,
	author={{
			MMBradford
		}}
	
	
		,
	journal={{Anal Biochem}}
		
			72
			
			,
	year={1976}
		
	

}

@incollection{b18,
	
	
		,
	title={{Doxorubicin-induced cardiotoxicity: From bioenergetic failure and cell death to cardiomyopathy}}
		,
	author={{
			FSCarvalho
		} and {
			ABurgeiro
		} and {
			RGarcia
		} and {
			AJMoreno
		} and {
			RACarvalho
		} and {
			PJOliveira
		}}
		
		
		
		
		
	
	
		,
	journal={{Med Res Rev}}
		
			34
			
			,
	year={2014}
		
	

}

@incollection{b19,
	
	
		,
	title={{Ultrastructural features of adriamycin-induced skeletal and cardiac muscle toxicity}}
		,
	author={{
			JHDoroshow
		} and {
			CTallent
		} and {
			JESchechter
		}}
		
		
	
	
		,
	journal={{Am J Pathol}}
		
			118
			
			,
	year={1985}
		
	

}

@incollection{b20,
	
	
		,
	title={{Exercise training attenuates acute doxorubicin-induced cardiac dysfunction}}
		,
	author={{
			AJChicco
		} and {
			CMSchneider
		} and {
			RHayward
		}}
		
		
	
	
		,
	journal={{Journal of cardiovascular pharmacology}}
		
			47
			
			,
	year={2006}
		
	

}

@incollection{b21,
	
	
		,
	title={{Effects of short-term endurance exercise training on acute doxorubicin-induced foxo transcription in cardiac and skeletal muscle}}
		,
	author={{
			ANKavazis
		} and {
			AJSmuder
		} and {
			SKPowers
		}}
		
		
	
	
		,
	journal={{Journal of applied physiology}}
		
			117
			
			,
	year={2014}
		
	

}

@incollection{b22,
	
	
		,
	title={{Nitric oxide and oxidative stress in brain and heart of normal rats treated with doxorubicin: Role of aminoguanidine}}
		,
	author={{
			AbdEl-Gawad
		} and {
			HMEl-Sawalhi
		} and {
			MM
		}}
		
		
	
	
		,
	journal={{Journal of biochemical and molecular toxicology}}
		
			18
			
			,
	year={2004}
		
	

}

@incollection{b23,
	
	
		,
	title={{Anthracyclines induce accumulation of iron in ferritin in myocardial and neoplastic cells: Inhibition of the ferritin iron mobilization pathway}}
		,
	author={{
			JKwok
		} and {
			DRichardson
		}}
		
	
	
		,
	journal={{Molecular pharmacology}}
		
			63
			
			,
	year={2003}
		
	

}

@incollection{b24,
	
	
		,
	title={{Glutathione transferase protects neuronal cultures against four hydroxynonenal toxicity}}
		,
	author={{
			CXie
		} and {
			MALovell
		} and {
			WRMarkesbery
		}}
		
		
	
	
		,
	journal={{Free Radical Biology and Medicine}}
		
			25
			
			,
	year={1998}
		
	

}

@incollection{b25,
	
	
		,
	title={{The multidrug resistance protein family}}
		,
	author={{
			PBorst
		} and {
			REvers
		} and {
			MKool
		} and {
			JWijnholds
		}}
		
		
		
	
	
		,
	journal={{Biochimica et biophysica acta}}
		
			1461
			
			,
	year={1999}
		
	

}

@incollection{b26,
	
	
		,
	title={{Transmembrane transport of endo-and xenobiotics by mammalian atp-binding cassette multidrug resistance proteins}}
		,
	author={{
			RGDeeley
		} and {
			CWestlake
		} and {
			SPCole
		}}
		
		
	
	
		,
	journal={{Physiol Rev}}
		
			86
			
			,
	year={2006}
		
	

}

@incollection{b27,
	
	
		,
	title={{Mrp1/gs-x pump atpase expression: Is this the explanation for the cytoprotection of the heart against oxidative stressinduced redox imbalance in comparison to skeletal muscle cells?}}
		,
	author={{
			MSKrause
		} and {
			LPOliveira
		} and {
			JrSilveira
		} and {
			EMVianna
		} and {
			DRRossato
		} and {
			JSAlmeida
		} and {
			BS
		}}
		
		
		
		
		
		
	
	
		,
	journal={{Cell Biochem Funct}}
		
			25
			
			,
	year={2007}
		
	

}

@incollection{b28,
	
	
		,
	title={{The anticancer agent doxorubicin disrupts mitochondrial energy metabolism and redox balance in skeletal muscle}}
		,
	author={{
			LAGilliam
		} and {
			KHFisher-Wellman
		} and {
			CTLin
		} and {
			JMMaples
		} and {
			BLCathey
		} and {
			PDNeufer
		}}
		
		
		
		
		
	
	
		,
	journal={{Free radical biology & medicine}}
		
			65
			
			,
	year={2013}
		
	

}

@incollection{b29,
	
	
		,
	title={{Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1)}}
		,
	author={{
			KNunoya
		} and {
			CEGrant
		} and {
			DZhang
		} and {
			SPCole
		} and {
			RGDeeley
		}}
		
		
		
		
	
	
		,
	journal={{Drug Metab Dispos}}
		
			31
			
			,
	year={2003}
		
	

}

@incollection{b30,
	
	
		,
	title={{Multidrug resistance-associated proteins: Expression and function in the central nervous system}}
		,
	author={{
			SDallas
		} and {
			DSMiller
		} and {
			RBendayan
		}}
		
		
	
	
		,
	journal={{Pharmacol Rev}}
		
			58
			
			,
	year={2006}
		
	

}

@incollection{b31,
	
	
		,
	title={{Overexpression of multidrug resistance-associated protein (mrp) increases resistance to natural product drugs}}
		,
	author={{
			CEGrant
		} and {
			GValdimarsson
		} and {
			DRHipfner
		} and {
			KCAlmquist
		} and {
			SPCole
		} and {
			RGDeeley
		}}
		
		
		
		
		
	
	
		,
	journal={{Cancer research}}
		
			54
			
			,
	year={1994}
		
	

}

@incollection{b32,
	
	
		,
	title={{The multidrug resistance protein mrp1 mediates the release of glutathione disulfide from rat astrocytes during oxidative stress}}
		,
	author={{
			JHirrlinger
		} and {
			JKoènig
		} and {
			DKeppler
		} and {
			JLindenau
		} and {
			JBSchulz
		} and {
			RDringen
		}}
		
		
		
		
		
	
	
		,
	journal={{Journal of Neurochemistry}}
		
			76
			
			,
	year={2001}
		
	

}