@incollection{,
	
					
					
					89EFAA2512D1819328179939C1AD4531
				,
	author={{DharmenderJaglan}},
	journal={{Global Journal of Medical Research}},
	journal={{GJMR}}2249-46180975-588810.34257/GJMR,
	address={Cambridge, United States},
	publisher={Global Journals Organisation}181718
}

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		,
	title={{Huntington's disease}}
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	author={{
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	title={{Huntingtin processing in pathogenesis of Huntington's disease}}
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}

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}

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}

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}

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		,
	title={{Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease}}
		,
	author={{
			CZuccato
		}}
	
	
		,
	journal={{Science}}
		
			293
			
			,
	year={2001}
		
	

}

@incollection{b65,
	
	
		,
	title={{Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series}}
		,
	author={{
			CLandles
		} and {
			GPBates
		}}
		
	
	
		,
	journal={{EMBO Rep}}
		
			5
			
			,
	year={2004}
		
	

}

@incollection{b66,
	
	
		,
	title={{Huntington disease: new insights on the role of huntingtin cleavage}}
		,
	author={{
			CLWellington
		} and {
			BRLeavitt
		} and {
			MRHayden
		}}
		
		
	
	
		,
	journal={{J Neural Transm Suppl}}
		
			58
			
			,
	year={2000}
		
	

}

@incollection{b67,
	
	
		,
	title={{The influence of huntingtin protein size on nuclear localization and cellular toxicity}}
		,
	author={{
			ASHackam
		}}
	
	
		,
	journal={{J Cell Biol}}
		
			141
			
			,
	year={1998}
		
	

}

@incollection{b68,
	
	
		,
	title={{Intranuclear huntingtin increases the expression of caspase-1 and induces apoptosis}}
		,
	author={{
			SHLi
		} and {
			SLam
		} and {
			ALCheng
		} and {
			XJLi
		}}
		
		
		
	
	
		,
	journal={{Hum Mol Genet}}
		
			9
			
			,
	year={2000}
		
	

}

@incollection{b69,
	
	
		,
	title={{Tissue-specific proteolysis of Huntingtin (htt) in human brain: evidence of enhanced levels of N-and C-terminal htt fragments in Huntington's disease striatum}}
		,
	author={{
			LMMende-Mueller
		} and {
			TToneff
		} and {
			SRHwang
		} and {
			MFChesselet
		} and {
			VYHook
		}}
		
		
		
		
	
	
		,
	journal={{J Neurosci}}
		
			21
			
			,
	year={2001}
		
	

}

@incollection{b70,
	
	
		,
	title={{The molecular biology of Huntington's disease}}
		,
	author={{
			LWHo
		}}
	
	
		,
	journal={{Psychol Med}}
		
			31
			
			,
	year={2001}
		
	

}

@incollection{b71,
	
	
		,
	title={{Energetics in the pathogenesis of neurodegenerative diseases}}
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	author={{
			MFBeal
		}}
	
	
		,
	journal={{Trends Neurosci}}
		
			23
			
			,
	year={2000}
		
	

}

@book{b72,
	
	
		,
	title={{Huntington's disease}}
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	author={{
			GPBates
		} and {
			KPMurphy
		}}
		
		,
	editor={Bates, G.P., Harper, P.S. & Jones, A.L.}
		
			,
	year={2002}
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	publisher={Oxford University Press}
			
			,
	address={Oxford, UK}
		
	

}

@incollection{b73,
	
	
		,
	title={{Huntingtin aggregation and toxicity in Huntington's disease}}
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	author={{
			GBates
		}}
	
	
		,
	journal={{Lancet}}
		
			361
			
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	year={2003}
		
	

}

@book{b74,
	
	
		,
	title={{The cell biology of Huntington's disease}}
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	author={{
			LJones
		}}
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	editor={Bates, G.P., Harper, P.S. & Jones, A.L.}
		
			,
	year={2002}
			,
	publisher={Oxford Univeristy Press}
			
			,
	address={Oxford, UK}
		
	

}

@book{b75,
	
	
		,
	title={{The neuropathology of Huntington's disease}}
		,
	author={{
			CAGutekunst
		} and {
			FNorflus
		} and {
			SMHersch
		}}
		
		
		,
	editor={Bates, G.P., Harper, P.S. & Jones, A.L.}
		
			,
	year={2002}
			,
	publisher={Oxford University Press}
			
			,
	address={Oxford, UK}
		
	

}

@incollection{b76,
	
	
		,
	title={{Apoptosis and caspases in neurodegenerative diseases}}
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	author={{
			RFriedlander
		}}
	
	
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			348
			
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}

@incollection{b77,
	
	
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	title={{Wild-type huntingtin protects from apoptosis upstream of caspase-3}}
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	author={{
			DRigamonti
		}}
	
	
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			20
			
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	year={2000}
		
	

}

@incollection{b78,
	
	
		,
	title={{Huntingtin-protein interactions and the pathogenesis of Huntington's disease}}
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	author={{
			SHLi
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			XJLi
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		,
	journal={{Trends Genet}}
		
			20
			
			,
	year={2004}
		
	

}

@incollection{b79,
	
	
		,
	title={{Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series}}
		,
	author={{
			CLandles
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			GPBates
		}}
		
	
	
		,
	journal={{EMBO Rep}}
		
			5
			
			,
	year={2004}
		
	

}

@incollection{b80,
	
	
		,
	title={{Lessons from animal models of Huntington's disease}}
		,
	author={{
			DCRubinsztein
		}}
	
	
		,
	journal={{Trends Genet}}
		
			18
			
			,
	year={2002}
		
	

}

@book{b81,
	
	
		,
	title={{The neuropathology of Huntington's disease}}
		,
	author={{
			CAGutekunst
		} and {
			FNorflus
		} and {
			SMHersch
		}}
		
		
		,
	editor={Bates, G.P., Harper, P.S. & Jones, A.L.}
		
			,
	year={2002}
			,
	publisher={Oxford University Press}
			
			,
	address={Oxford, UK}
		
	

}

@incollection{b82,
	
	
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	author={{
			PHarjes
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			EEWanker
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		,
	journal={{Trends Biochem Sci}}
		
			28
			
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	year={2003}
		
	

}

@incollection{b83,
	
	
		,
	title={{Huntingtin-protein interactions and the pathogenesis of Huntington's disease}}
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	author={{
			SHLi
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			XJLi
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	journal={{Trends Genet}}
		
			20
			
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	year={2004}
		
	

}

@incollection{b84,
	
	
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	title={{The Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes}}
	
	
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}

@incollection{b85,
	
	
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			FConde
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			MFBeal
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			PHantraye
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			59
			
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	year={1999}
		
	

}

@incollection{b86,
	
	
		,
	title={{Regional mitochondrial respiratory activity in Huntington's disease brain}}
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	author={{
			WABrennan
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			Jr
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			EDBird
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@incollection{b87,
	
	
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			DCRubinsztein
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			59
			
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}

@incollection{b88,
	
	
		,
	title={{Lessons from animal models of Huntington's disease}}
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	author={{
			DCRubinsztein
		}}
	
	
		,
	journal={{Trends Genet}}
		
			18
			
			,
	year={2002}
		
	

}

@incollection{b89,
	
	
		,
	title={{}}
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	author={{
			JPVonsattel
		} and {
			MDifiglia
		} and {
			Huntington Disease
		}}
		
		
	
	
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			57
			
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	year={1998}
		
	

}

@incollection{b90,
	
	
		,
	title={{Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias}}
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	author={{
			MDifiglia
		}}
	
	
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	,
	note={Nature}

}

@incollection{b91,
	
	
		,
	title={{Toward understanding the molecular pathology of Huntington's disease}}
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	author={{
			CLWellington
		} and {
			RRBrinkman
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			JRO' Kusky
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			MRHayden
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	journal={{Brain Pathol}}
		
			7
			
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	year={1997}
		
	

}

@incollection{b92,
	
	
		,
	title={{Recent advances on the pathogenesis of Huntington's disease}}
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	author={{
			ÅPetersén
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			KMani
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			PBrundin
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	journal={{Exp Neurol}}
		
			157
			
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	year={1999}
		
	

}

@incollection{b93,
	
	
		,
	title={{In situ evidence for DNA fragmentation in Huntington's disease striatum and Alzheimer's disease temporal lobes}}
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	author={{
			MDragunow
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	journal={{Neuroreport}}
		
			6
			
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	year={1995}
		
	

}

@incollection{b94,
	
	
		,
	title={{Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models}}
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	author={{
			CPortera-Cailliau
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			JCHedreen
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			DLPrice
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			VEKoliatsos
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			15
			
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	year={1995}
		
	

}

@incollection{b95,
	
	
		,
	title={{DNA end labeling (TUNEL) in Huntington's disease and other neuropathological conditions}}
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	author={{
			LBThomas
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	journal={{Exp Neurol}}
		
			133
			
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}

@incollection{b96,
	
	
		,
	title={{Apoptosis in Huntington's disease}}
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	author={{
			MHickey
		} and {
			MChesselet
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		,
	journal={{Prog Neuropsychopharmacol Biol Psychiatry}}
		
			27
			
			,
	year={2003}
		
	

}

@incollection{b97,
	
	
		,
	title={{Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract}}
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	author={{
			YGoldberg
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	journal={{Nat Genet}}
		
			13
			
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	year={1996}
		
	

}

@incollection{b98,
	
	
		,
	title={{Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease}}
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	author={{
			MChen
		}}
	
	
		,
	journal={{Nat Med}}
		
			6
			
			,
	year={2000}
		
	

}

@incollection{b99,
	
	
		,
	title={{Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease}}
		,
	author={{
			VOna
		}}
	
	
		,
	journal={{Nature}}
		
			399
			
			,
	year={1999}
		
	

}

@incollection{b100,
	
	
		,
	title={{Caspase-8 is required for cell death induced by expanded polyglutamine repeats}}
		,
	author={{
			ISanchez
		}}
	
	
		,
	journal={{Neuron}}
		
			22
			
			,
	year={1999}
		
	

}

@incollection{b101,
	
	
		,
	title={{Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series}}
		,
	author={{
			Landles
		} and {
			GPBates
		}}
		
	
	
		,
	journal={{EMBO Rep}}
		
			5
			
			,
	year={2004}
		
	

}

@incollection{b102,
	
	
		,
	title={{Huntington disease: new insights on the role of huntingtin cleavage}}
		,
	author={{
			CLWellington
		} and {
			BRLeavitt
		} and {
			MRHayden
		}}
		
		
	
	
		,
	journal={{J Neural Transm Suppl}}
		
			58
			
			,
	year={2000}
		
	

}

@incollection{b103,
	
	
		,
	title={{Apoptosis in Huntington's disease}}
		,
	author={{
			MHickey
		} and {
			MChesselet
		}}
		
	
	
		,
	journal={{Prog Neuropsychopharmacol Biol Psychiatry}}
		
			27
			
			,
	year={2003}
		
	

}

@incollection{b104,
	
	
		,
	title={{Cytochrome C and caspase-9 expression in Huntington's disease}}
		,
	author={{
			TKiechle
		}}
	
	
		,
	journal={{Neuromolecular Med}}
		
			1
			
			,
	year={2002}
		
	

}

@incollection{b105,
	
	
		,
	title={{Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity}}
		,
	author={{
			FCNucifora
		} and {
			Jr
		}}
		
	
	
		,
	journal={{Science}}
		
			291
			
			,
	year={2001}
		
	

}

@incollection{b106,
	
	
		,
	title={{Expression of apoptosis-related markers in human HD brains}}
		,
	author={{
			JCVis
		}}
	
	
		,
	journal={{Acta Neuropathol}}
		
			109
			
			,
	year={2005}
		
	

}

@incollection{b107,
	
	
		,
	title={{The influence of huntingtin protein size on nuclear localization and cellular toxicity}}
		,
	author={{
			ASHackam
		}}
	
	
		,
	journal={{J Cell Biol}}
		
			141
			
			,
	year={1998}
		
	

}