@incollection{,
	
					
					
					D1314CAF1DEF32107047FA7506ACF95D
				,
	author={{Feyera GemedaDima} and {Jimma University, Ethiopia}},
	journal={{Global Journal of Medical Research}},
	journal={{GJMR}}2249-46180975-588810.34257/GJMR,
	address={Cambridge, United States},
	publisher={Global Journals Organisation}1812335
}

@incollection{b0,
	
	
		,
	title={{Bacterial virulence as a target for antimicrobial chemotherapy}}
		,
	author={{
			LEAlksne
		} and {
			SJProjan
		}}
		
	
	
		,
	journal={{Current Opinions in Biotechnology}}
		
			11
			
			,
	year={2000}
		
	

}

@incollection{b1,
	
	
		,
	title={{mycobacterium tuberculosis h37rv: in silico drug targets identification by metabolic pathways analysis Department of Biotechnology}}
		,
	author={{
			AsadAmir
		} and {
			KhyatiRana
		} and {
			ArvindArya
		} and {
			NeeleshKapoor
		} and {
			HirdeshKumar
		} and {
			Mohd AsifSiddiqui
		}}
		
		
		
		
		
	
	
		,
	journal={{India International Journal of Evolutionary Biology}}
		
			58
			,
	year={2014. 250005. February 2014}
		
		
			Meerut Institute of Engineering and Technology, N.H
		
	
	,
	note={Published 25}

}

@incollection{b2,
	
	
		,
	title={{Mycobacterial outer membrane is a lipid bilayer and the inner membrane is unusually rich in diacyl phosphatedylinositol diman nosides}}
		,
	author={{
			Bansal-Mutalik
		} and {
			HNikaido
		} and {
			)
		}}
		
		
	
	
		,
	journal={{Proc. Natl Acad. Sci. USA}}
		
			111
			
			,
	year={2014}
		
	

}

@incollection{b3,
	
	
		,
	title={{Antibacterial agents that inhibit two component signal transduction systems}}
		,
	author={{
			JFBarrett
		} and {
			RMGoldschmidt
		} and {
			LELawrence
		} and {
			BFoleno
		} and {
			RChen
		}}
		
		
		
		
	
	
		,
	journal={{Proceedings of National Academy of Sciences}}
		
			95
			53
			,
	year={1998}
		
	

}

@incollection{b4,
	
	
		,
	title={{Targeting the formation of the cell wall core of M. tuberculosis}}
		,
	author={{
			CEBarry
		} and {
			DCCrick
		} and {
			MRMcneil
		}}
		
		
	
	
		,
	journal={{Infect. Disord. Drug Targets}}
		
			7
			
			,
	year={2007}
		
	

}

@incollection{b5,
	
	
		,
	title={{Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling}}
		,
	author={{
			JCBetts
		} and {
			PTLukey
		} and {
			LCRobb
		} and {
			RAMcadam
		} and {
			KDuncan
		}}
		
		
		
		
	
	
		,
	journal={{Molecular Microbiology}}
		
			43
			
			,
	year={2002}
		
	

}

@incollection{b6,
	
	
		,
	title={{Signature gene expression profiles discriminate between isoniazid thiolactomycin and triclosan treated Mycobacterium tuberculosis}}
		,
	author={{
			JCBetts
		} and {
			AMclaren
		} and {
			MGLennon
		} and {
			FMKelly
		} and {
			PTLukey
		}}
		
		
		
		
	
	
		,
	journal={{Antimicrobiology Agents and Chemotheraphy}}
		
			47
			
			,
	year={2003}
		
	

}

@incollection{b7,
	
	
		,
	title={{Infectious Diseases Society of America: treatment of tuberculosis}}
		,
	author={{
			HMBlumberg
		}}
	
	
		,
	journal={{American Journal Respiration and Critical Care Medicine}}
		
			167
			
			,
	year={2003}
			,
	publisher={American Thoracic Society}
		
	

}

@incollection{b8,
	
	
		,
	title={{Mycobacterium bovis BCG response regulator essential for hypoxic dormancy}}
		,
	author={{
			CBoon
		} and {
			TDick
		}}
		
	
	
		,
	journal={{J. Bacteriol}}
		
			184
			
			,
	year={2002}
		
	

}

@incollection{b9,
	
	
		,
	title={{Bacterial iron transport: mechanisms genetics, and regulation}}
		,
	author={{
			VBraun
		} and {
			KHantke
		} and {
			WKoster
		}}
		
		
	
	
		,
	journal={{Metal Ions Biology System}}
		
			35
			
			,
	year={1998}
		
	

}

@incollection{b10,
	
	
		,
	title={{Genome plasticity of BCG and impact on vaccine efficacy}}
		,
	author={{
			RBrosch
		} and {
			SVGordon
		} and {
			TGarnier
		} and {
			KEiglmeier
		} and {
			WFrigui
		}}
		
		
		
		
		10.1073/pnas.0700869104
	
	
		,
	journal={{Proc Natl Acad Sci U S A}}
		
			104
			1737219
			,
	year={2007}
		
	

}

@incollection{b11,
	
	
		,
	title={{A parallel intraphagosomal survival strategy shared by Mycobacterium tuberculosis and Salmonella enterica}}
		,
	author={{
			NBuchmeier
		} and {
			ABlancpotard
		} and {
			SEhrt
		} and {
			DPiddington
		} and {
			LRiley
		} and {
			EAGroisman
		}}
		
		
		
		
		
	
	
		,
	journal={{Molocular Microbiology}}
		
			35
			
			,
	year={2000}
		
	

}

@incollection{b12,
	
	
		,
	title={{Treatment and outcome analysis of 2005 patients with multi-drug resistant tuberculosis}}
		,
	author={{
			EDChan
		} and {
			VLaurel
		} and {
			MJStrand
		} and {
			JFChan
		} and {
			MLHuynh
		} and {
			MGoble
		} and {
			MDIseman
		}}
		
		
		
		
		
		
	
	
		,
	journal={{American J Respiration Critial Care Medicine}}
		
			169
			
			,
	year={2004}
		
	

}

@incollection{b13,
	
	
		,
	title={{Exploiting current understanding of antibiotic action for discovery of new drugs}}
		,
	author={{
			IChopra
		} and {
			LHesse
		} and {
			AJNeill
		}}
		
		
	
	
		,
	journal={{Journal of Applied. Microbiology}}
		
			92
			
			,
	year={2002}
		
	

}

@incollection{b14,
	
	
		,
	title={{Mycobacterium tuber culosis Can Utilize Heme as an Iron Source}}
		,
	author={{
			JMChristopher
		} and {
			MNiederweis
		}}
		
	
	
		,
	journal={{JOURNAL OFBACTERIOLOGY}}
		
			193
			7
			
			,
	year={2011}
		
	

}

@incollection{b15,
	
	
		,
	title={{Comparative mycobacterial genomics as a tool for drug target and antigen discovery}}
		,
	author={{
			SCole
		}}
	
	
		,
	journal={{Eur. Respir. J}}
		
			36
			
			,
	year={2002}
		
	

}

@incollection{b16,
	
	
		,
	title={{Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence}}
		,
	author={{
			STCole
		} and {
			RBrosch
		} and {
			JParkhill
		} and {
			TGarnier
		} and {
			CChurcher
		} and {
			DHarris
		}}
		
		
		
		
		
	
	
		,
	journal={{Nature}}
		
			393
			
			,
	year={1998}
		
	

}

@incollection{b17,
	
	
		,
	title={{The role of Mtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice}}
		,
	author={{
			JLDahl
		}}
	
	
		,
	journal={{Procilamation National Acadamic Science USA}}
		
			100
			
			,
	year={2003}
		
	

}

@incollection{b18,
	
	
		,
	title={{Characterization of a two component system devR-devS, of Mycobacterium tuberculosis}}
		,
	author={{
			NDasgupta
		} and {
			VKapur
		} and {
			KKSingh
		} and {
			TKDas
		} and {
			SSachdeva
		} and {
			KJyothisri
		}}
		
		
		
		
		
	
	
		,
	journal={{Tuberculosis and Lung Diseases}}
		
			80
			
			,
	year={2000}
		
	

}

@incollection{b19,
	
	
		,
	title={{Critical assessment of smear positive pulmonary tuberculosis patients after chemotherapy under the district tuberculosis programe}}
		,
	author={{
			MDatta
		} and {
			MPRadhamani
		} and {
			RSelvaraj
		} and {
			CNParamasivan
		} and {
			BNGopalan
		} and {
			CRSudeendra
		} and {
			RPrabhakar
		}}
		
		
		
		
		
		
	
	
		,
	journal={{Tuberculosis and Lung Diseases}}
		
			74
			
			,
	year={1993}
		
	

}

@incollection{b20,
	
	
		,
	title={{Mycobacterium bovis in free-living and captive wildlife, including farmed deer}}
		,
	author={{
			GWDe Lisle
		} and {
			CGMackintosh
		} and {
			RGBengis
		}}
		
		
	
	
		,
	journal={{Rev Sci Tech}}
		
			20
			11288522
			,
	year={2001}
		
	

}

@incollection{b21,
	
	
		,
	title={{The salicylatederived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages}}
		,
	author={{
			DeVoss
		} and {
			JJRutter
		} and {
			KSchroeder
		} and {
			BGSu
		} and {
			HZhu
		} and {
			YBarry
		} and {
			EC
		}}
		
		
		
		
		
		
	
	
		,
	booktitle={{Proceedings of National Academy of Sciences}}
				National Academy of Sciences
		
			,
	year={2000}
			97
			
		
	

}

@incollection{b22,
	
	
		,
	title={{Production of cytokines in sarcoid lymph nodes: preferential expression of interleukin-1 beta and interferon-gamma genes}}
		,
	author={{
			ODevergne
		} and {
			DEmilie
		} and {
			MPeuchmaur
		} and {
			MCCrevon
		} and {
			MFDiagay
		} and {
			PGalanaud
		}}
		
		
		
		
		
	
	
		,
	journal={{Human Pathology}}
		
			23
			
			,
	year={1992}
		
	

}

@incollection{b23,
	
	
		,
	title={{Microbial genomics and novel antibiotic discovery: new technology to search for new drugs}}
		,
	author={{
			TJDougherty
		} and {
			JFBarrett
		} and {
			MJPucci
		}}
		
		
	
	
		,
	journal={{Curr. Pharm. Des}}
		
			8
			
			,
	year={2002}
		
	

}

@incollection{b24,
	
	
		,
	title={{In situ detection of Mycobacterium tuberculosis transcripts in human lung granulomas reveals differential gene expression in necrotic lesions}}
		,
	author={{
			GFenhalls
		} and {
			LStevens
		} and {
			LMoses
		} and {
			JBezuidenhout
		} and {
			JCBetts
		}}
		
		
		
		
	
	
		,
	journal={{Infectiou Immunulogy}}
		
			70
			
			,
	year={2002}
		
	

}

@incollection{b25,
	
	
		,
	author={{
			RDFleischmann
		} and {
			MDAdams
		} and {
			OWhite
		} and {
			RAClayton
		} and {
			EFKirkness
		}}
		
		
		
		
	
	
		,
	booktitle={{Whole genome random sequencing and assembly of Haemophilus influenzae Rd}}
				
			,
	year={1995}
			269
			
		
	

}

@incollection{b26,
	
	
		,
	title={{Adverse reactions to first-line antituberculosis drugs}}
		,
	author={{
			EJForget
		} and {
			DMenzies
		}}
		
	
	
		,
	journal={{Expert Opinion Drug Safety}}
		
			5
			231249
			,
	year={2006}
		
	

}

@incollection{b27,
	
	
		,
	title={{Searching for drug targets in microbial genomes}}
		,
	author={{
			MYGalperin
		} and {
			EVKoonin
		}}
		
	
	
		,
	journal={{Current Opinion in Biotechnology}}
		
			10
			6
			
			,
	year={1999}
		
	

}

@incollection{b28,
	
	
		,
	title={{The effects of streptomycin or dihydro streptomycin binding to 16S RNA or to 30S ribosomal subunits}}
		,
	author={{
			RTGarvin
		} and {
			DKBiswas
		} and {
			LGorini
		}}
		
		
	
	
		,
	booktitle={{Proceedings of National Academy of Sciences}}
				National Academy of Sciences
		
			,
	year={1974}
			71
			
		
	

}

@incollection{b29,
	
	
		,
	title={{Initial sequencing and analysis of the human genome}}
	
	
		,
	journal={{Genome International Consortium (GIC)}}
		
			409
			
			,
	year={2001}
		
	
	,
	note={Nature}

}

@incollection{b30,
	
	
		,
	title={{A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosis}}
		,
	author={{
			MSGlickman
		}}
	
	
		,
	journal={{Molecular Cell}}
		
			5
			
			,
	year={2000}
		
	

}

@incollection{b31,
	
	
		,
	title={{Microbial pathogenesis of Mycobacterium tuberculosis dawn of a discipline}}
		,
	author={{
			MSGlickman
		} and {
			WBJacobs
		}}
		
	
	
		,
	journal={{Cell}}
		
			104
			
			,
	year={2001}
		
	

}

@incollection{b32,
	
	
		,
	title={{Executive Summary of the Scientific Blueprint for TB Drug Development}}
	
	
		,
	booktitle={{Global Alliance for Tuberculosis Drug Development (GAFTDD)}}
				
			,
	year={2001}
			81
			
		
	

}

@incollection{b33,
	
	
		,
	title={{Chemistry and biology of siderophores}}
		,
	author={{
			RCHider
		} and {
			XKong
		}}
		
	
	
		,
	journal={{Nat. Prod. Rep}}
		
			27
			
			,
	year={2010}
		
	

}

@incollection{b34,
	
	
		,
	title={{Two component and phosphorelay signal transduction}}
		,
	author={{
			JAHoch
		}}
	
	
		,
	journal={{Current Opinion Microbiology}}
		
			3
			
			,
	year={2000}
		
	

}

@incollection{b35,
	
	
		,
	title={{A new class of antituberculosis agents}}
		,
	author={{
			PBJones
		} and {
			NMParrish
		} and {
			TAHouston
		} and {
			AStapon
		} and {
			NPBansal
		} and {
			JDDick
		}}
		
		
		
		
		
	
	
		,
	journal={{Journal Medical Chemistry}}
		
			43
			
			,
	year={2000}
		
	

}

@incollection{b36,
	
	
		,
	title={{The KEGG data bases at Genome Net}}
		,
	author={{
			MKanehisa
		} and {
			SGoto
		} and {
			SKawashima
		} and {
			ANakaya
		}}
		
		
		
	
	
		,
	journal={{Nucleic Acids Res}}
		
			30
			1
			
			,
	year={2002}
		
	

}

@incollection{b37,
	
	
		,
	title={{Inadequacy of the current WHO retreatment regimen in a central Siberian prison: treatment failure and MDR-TB}}
		,
	author={{
			MEKimerling
		} and {
			HKluge
		} and {
			NVezhnina
		} and {
			TIacovazzi
		} and {
			TDemeulenaere
		} and {
			FPortaels
		}}
		
		
		
		
		
	
	
		,
	journal={{International J Tuberculosis Lung Disease}}
		
			3
			
			,
	year={1999}
		
	

}

@incollection{b38,
	
	
		,
	title={{Biochemistry and molecular genetics of cell-wall lipid biosynthesis in mycobacteria}}
		,
	author={{
			PEKolattukudy
		} and {
			NDFernandes
		} and {
			AKAzad
		} and {
			AMFitzmaurice
		} and {
			TDSirakova
		}}
		
		
		
		
	
	
		,
	journal={{Molecular Microbiology}}
		
			24
			2
			
			,
	year={1997}
		
	

}

@incollection{b39,
	
	
		,
	title={{Iron: mammalian defense systems, mechanisms of disease, and chelation therapy approaches}}
		,
	author={{
			GJKontoghiorghes
		} and {
			EDWeinberg
		}}
		
	
	
		,
	journal={{Blood Review}}
		
			9
			1
			
			,
	year={1995}
		
	

}

@incollection{b40,
	
	
		,
	title={{Designer arrays for defined mutant analysis to detect genes essential for survival of Mycobacterium tuberculosis in mouse lungs}}
		,
	author={{
			Lamichhane
		}}
	
	
		,
	journal={{Infection and Immunity}}
		
			73
			
			,
	year={2005}
		
	

}

@incollection{b41,
	
	
		,
	title={{The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site}}
		,
	author={{
			PLemagueres
		} and {
			HIm
		} and {
			JEbalunode
		} and {
			UStrych
		} and {
			MJBenedik
		} and {
			JMBriggs
		} and {
			HKohn
		} and {
			KLKrause
		}}
		
		
		
		
		
		
		
	
	
		,
	journal={{Biochemistry}}
		
			44
			
			,
	year={2005}
		
	

}

@incollection{b42,
	
	
		,
	title={{Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence conferring siderophore mycobactin}}
		,
	author={{
			EN QLuis
		} and {
			SJason
		} and {
			AKThomas
		} and {
			HWPaul
		} and {
			TWChristopher
		}}
		
		
		
		
	
	
		,
	journal={{Chemical Biology}}
		
			5
			11
			
			,
	year={1998}
		
	

}

@incollection{b43,
	
	
		,
	title={{Drug targeting Mycobacterium tuberculosis cell wall synthesis: genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate based screen for inhibitors of conversion of dTDP-glucose to dTDPrhamnose}}
		,
	author={{
			YMa
		} and {
			RJStern
		} and {
			MSScherman
		} and {
			VDVissa
		} and {
			WYan
		} and {
			VCJones
		} and {
			FZhang
		} and {
			SGFranzblau
		} and {
			WHLewis
		} and {
			MRMcneil
		}}
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Antimicrobial Agents and Chemotherapy}}
		
			45
			
			,
	year={2001}
		
	

}

@incollection{b44,
	
	
		,
	title={{Mutation of tly A confers capreomycin resistance in Mycobacterium tuberculosis}}
		,
	author={{
			CEMaus
		}}
	
	
		,
	journal={{Antimicrobial Agents and Chemotherapy}}
		
			49
			
			,
	year={2005}
		
	

}

@incollection{b45,
	
	
		,
	title={{Microbial persistence}}
		,
	author={{
			WMcdermott
		}}
	
	
		,
	journal={{Yale. J. Biology and Medicine}}
		
			30
			
			,
	year={2000}
		
	

}

@incollection{b46,
	
	
		,
	title={{Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase}}
		,
	author={{
			JDMckinney
		}}
	
	
		,
	journal={{Nature}}
		
			406
			
			,
	year={2000}
		
	

}

@incollection{b47,
	
	
		,
	author={{
			KMikusova
		} and {
			MMikus
		} and {
			GSBesra
		} and {
			IHannock
		} and {
			PJBrennan
		}}
		
		
		
		
	
	
		,
	booktitle={{Chemistry of the bacterial cell wall}}
				,
	editor={
			WNRom
			SMGaray
		}
		Boston
		
			,
	year={1996}
			
		
	

}

@incollection{b48,
	
	
		,
	title={{Biogenesis of the mycobacterial cell wall and the site of action of ethambutol}}
		,
	author={{
			KMikusova
		} and {
			RASlayden
		} and {
			GSBesra
		} and {
			PJBrennan
		}}
		
		
		
	
	
		,
	journal={{Antimicrobial Agents and Chemotheraphy}}
		
			39
			
			,
	year={1995}
		
	

}

@incollection{b49,
	
	
		,
	title={{Treatment of multiple drug resistant tuberculosis (MDRTB) in Iran}}
		,
	author={{
			SMMirsaeidi
		} and {
			PTabarsi
		} and {
			KKhoshnood
		} and {
			MVPooramiri
		} and {
			Rowhani
		} and {
			ARahbar
		} and {
			SDMansoori
		} and {
			HMasjedi
		} and {
			SZahirifard
		} and {
			FMohammadi
		} and {
			PFarnia
		} and {
			MRMasjedi
		} and {
			AAVelayati
		}}
		
		
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{International Journal Infectious Disease}}
		
			9
			
			,
	year={2005}
		
	

}

@incollection{b50,
	
	
		,
	title={{Tuberculosis drug resistance a global threat}}
		,
	author={{
			JBNachega
		} and {
			REChaisson
		}}
		
	
	
		,
	journal={{Clincal. Infectious Disease}}
		
			36
			
			,
	year={2003}
		
	

}

@incollection{b51,
	
	
		,
	title={{Side effects of drugs used to treat tuberculosis}}
		,
	author={{
			RVNewton
		}}
	
	
		,
	journal={{Scott. Medicine Journal}}
		
			20
			
			,
	year={1975}
		
	

}

@incollection{b52,
	
	
		,
	title={{Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis}}
		,
	author={{
			HDPark
		}}
	
	
		,
	journal={{Molecular Microbiology}}
		
			48
			
			,
	year={2003}
		
	

}

@incollection{b53,
	
	
		,
	author={{
			NMParrish
		} and {
			FPKuhajda
		} and {
			HSHeine
		} and {
			WRBishai
		} and {
			JDDick
		}}
		
		
		
		
	
	
		,
	booktitle={{Antimycobacterial activity of cerulenin and its effects on lipid biosynthesis}}
				
			,
	year={1999}
			43
			
		
	

}

@incollection{b54,
	
	
		,
	title={{An essential role for phoP in Mycobacterium tuberculosis virulence}}
		,
	author={{
			EPerez
		} and {
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}

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@book{b82,
	
	
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	note={Molecular genetics of mycobacteria}

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@book{b83,
	
	
		,
	title={{}}
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	author={{
			DCWashington
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	publisher={ASM Press}
			
		
	

}