@incollection{,
	
					
					
					298D51EEA6FD7D6B42A3E16987B74CEE
				,
	journal={{Global Journal of Medical Research}},
	journal={{GJMR}}2249-46180975-588810.34257/GJMR,
	address={Cambridge, United States},
	publisher={Global Journals Organisation}1821917
}

@incollection{b0,
	
	
		,
	title={{Agespecific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies}}
		,
	author={{
			SLewington
		} and {
			RClarke
		} and {
			NQizilbash
		} and {
			RPeto
		} and {
			RCollins
		}}
		
		
		
		
	
	
		,
	journal={{Lancet}}
		
			360
			
			,
	year={2002}
		
	
	,
	note={Prospective Studies Collaboration}

}

@incollection{b1,
	
	
		,
	title={{No evidence that frailty modifies the positive impact of antihypertensive treatment in very elderly people: an investigation of the impact of frailty upon treatment effect in the Hypertension in the Very Elderly Trial (HYVET) study, a double-blind, placebo-controlled study of antihypertensives in people with hypertension aged 80 and over}}
		,
	author={{
			JWarwick
		} and {
			EFalaschetti
		} and {
			KRockwood
		} and {
			AMitnitski
		} and {
			LThijs
		} and {
			NBeckett
		} and {
			CBulpitt
		} and {
			RPeters
		}}
		
		
		
		
		
		
		
	
	
		,
	journal={{BMC Med}}
		
			13
			78
			,
	year={2015}
		
	

}

@incollection{b2,
	
	
		,
	title={{A randomized trial of intensive versus standard blood-pressure control}}
		,
	author={{
			JTWright
		} and {
			JDWilliamson
		} and {
			PKWhelton
		}}
		
		
	
	
		,
	journal={{N Engl J Med}}
		
			373
			
			,
	year={2015}
		
		
			SPRINT Research Group
		
	

}

@incollection{b3,
	
	
		,
	title={{Is blood pressure control for stroke prevention the correct goal? The lost opportunity of preventing hypertension}}
		,
	author={{
			GHoward
		} and {
			MBanach
		} and {
			MCushman
		} and {
			DCGoff
		} and {
			VJHoward
		} and {
			DTLackland
		} and {
			JMcvay
		} and {
			JFMeschia
		} and {
			PMuntner
		} and {
			SOparil
		} and {
			MRightmyer
		} and {
			HATaylor
		}}
		
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Stroke}}
		
			46
			
			,
	year={2015}
		
	

}

@incollection{b4,
	
	
		,
	title={{Age, blood pressure targets, and guidelines. Rift between those who preach, those who teach, and those who treat?}}
		,
	author={{
			FHMesserli
		} and {
			SBangalore
		} and {
			AWMesserli
		}}
		
		
	
	
		,
	journal={{Circulation}}
		
			138
			
			,
	year={2018}
		
	

}

@incollection{b5,
	
	
		,
	title={{Hypertension in the frail elderly}}
		,
	author={{
			BJMaterson
		} and {
			MGarcia-Estrada
		} and {
			RAPreston
		}}
		
		
	
	
		,
	journal={{J Am Soc Hypertens}}
		
			10
			
			,
	year={2016}
		
	

}

@incollection{b6,
	
	
		,
	title={{Treatment of hypertension in the oldest old: a critical role for frailty?}}
		,
	author={{
			MMuller
		} and {
			YMSmulders
		} and {
			PWDe Leeuw
		}}
		
		
	
	
		,
	journal={{Hypertension}}
		
			63
			
			,
	year={2014}
		
	

}

@incollection{b7,
	
	
		,
	title={{PCNA Guideline for the prevention, detection, ealuation, and management of high blood pressure in adults. A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines}}
		10.1016/j.jacc.2017.11.006
		
	
	
		,
	journal={{Journal of the American College of Cardiology}}
		
			,
	year={November 2017}
		
	

}

@incollection{b8,
	
	
		,
	title={{Orthostatic hypotension: framework of the syndrome}}
		,
	author={{
			JENaschitz
		} and {
			IRosner
		}}
		
	
	
		,
	journal={{Postgrad Med J}}
		
			83
			
			,
	year={2007}
		
	

}

@incollection{b9,
	
	
		,
	title={{A short history of automated office blood pressure -15 years to SPRINT}}
		,
	author={{
			MGMyers
		}}
	
	
		,
	journal={{J Clin Hypertens}}
		
			18
			
			,
	year={2016}
		
	

}

@incollection{b10,
	
	
		,
	title={{The implications of blood pressure measurement methods on treatment targets for blood pressure}}
		,
	author={{
			GBakris
		}}
	
	
		,
	journal={{Circulation}}
		
			134
			
			,
	year={2016}
		
	

}

@incollection{b11,
	
	
		,
	title={{Ambulatory blood pressure monitoring in older nursing home residents: diagnostic and prognostic role}}
		,
	author={{
			EMossello
		} and {
			MCPieraccioli
		} and {
			SZanieri
		}}
		
		
	
	
		,
	journal={{J Am Med Dir Assoc}}
		
			13
			
			,
	year={2012}
		
	

}

@incollection{b12,
	
	
		,
	title={{Policy statement of the World Hypertension League on noninvasive blood pressure measurement devices and blood pressure measurement in the clinical or community setting}}
		,
	author={{
			NR CCampbell
		} and {
			AEBerbari
		} and {
			LCloutier
		}}
		
		
	
	
		,
	journal={{J Clin Hypertens}}
		
			16
			
			,
	year={2014}
		
	

}

@incollection{b13,
	
	
		,
	title={{The patient with supine hypertension and orthostatic hypotension: a clinical dilemma}}
		,
	author={{
			JENaschitz
		} and {
			GSlobodin
		} and {
			NElias
		}}
		
		
	
	
		,
	journal={{Postgrad Med J}}
		
			82
			
			,
	year={2006}
		
	

}

@incollection{b14,
	
	
		,
	title={{Interarm blood pressure difference in a poststroke population}}
		,
	author={{
			GaynorEBrewer
		} and {
			LMellon
		} and {
			LHall
		} and {
			PHorgan
		} and {
			FShelley
		} and {
			EDolan
		} and {
			EHickey
		} and {
			ABennett
		} and {
			KWilliams
		} and {
			DJ
		}}
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{J Am Soc Hypertens}}
		
			9
			
			,
	year={2017 Sep: 11}
		
	
	,
	note={E 5}

}

@incollection{b15,
	
	
		,
	title={{What is the international consensus?}}
		,
	author={{
			EO'brien
		} and {
			GParati
		} and {
			GStergiou
		}}
		
		
	
	
		,
	journal={{Hypertension}}
		
			68
			
			,
	year={2013}
		
	

}

@incollection{b16,
	
	
		,
	title={{Systolic blood pressure decline in very old individuals is explained by deteriorating health: Longitudinal changes from Umea85+/GERDA}}
		,
	author={{
			BWeidung
		} and {
			AToots
		} and {
			PNordstrom
		}}
		
		
	
	
		,
	journal={{Medicine}}
		
			
			,
	year={2017}
		
	

}

@incollection{b17,
	
	
		,
	title={{Redefining hypertensionassessing the New Blood-Pressure Guidelines}}
		,
	author={{
			GBakris
		} and {
			MSorrentino
		}}
		
		10.1056/NEJMp1716193
	
	
		,
	journal={{N Engl J Med}}
		
			,
	year={2018. Jan}
		
	

}

@incollection{b18,
	
	
		,
	title={{Hypertension and frailty in older adults}}
		,
	author={{
			SassakiEAprahamian
		} and {
			DosSantos
		} and {
			MF
		}}
		
		
	
	
		,
	journal={{J Clin Hypertens (Greenwich)}}
		
			2017
			
		
	

}

@book{b19,
	
	
		,
	title={{Association between frailty and hypertension prevalence, treatment, and control in the elderly Korean population}}
		,
	author={{
			MGKang
		} and {
			SWKim
		} and {
			SJYoon
		}}
		
		
		2017: 7: 7542
		
	

}

@incollection{b20,
	
	
		,
	title={{Novel use of Kaplan-Meier methods to explain age and gender differences in hypertension control rates}}
		,
	author={{
			KRBailey
		} and {
			BRGrossardt
		} and {
			JWGraves
		}}
		
		
	
	
		,
	journal={{Hypertension}}
		
			51
			
			,
	year={2008}
		
	

}

@incollection{b21,
	
	
		,
	title={{Effect of Chlorthalidone, Amlodipine, and Lisinopril on Visit-to-Visit Variability of Blood Pressure: Results From the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial}}
		,
	author={{
			PMuntner
		} and {
			EBLevitan
		} and {
			AILynch
		} and {
			LMSimpson
		} and {
			JWhittle
		}}
		
		
		
		
	
	
		,
	journal={{J Clin Hypertens}}
		
			16
			
			,
	year={2014}
		
	

}

@incollection{b22,
	
	
		,
	title={{Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial}}
		,
	author={{
			BDahlöf
		} and {
			PSSever
		} and {
			NRPoulter
		} and {
			HWedel
		} and {
			DGBeevers
		} and {
			MCaulfield
		} and {
			RCollins
		} and {
			SEKjeldsen
		} and {
			AKristinsson
		} and {
			GTMcinnes
		} and {
			JMehlsen
		} and {
			MNieminen
		} and {
			EO'brien
		} and {
			JOstergren
		} and {
			Ascot Investigators
		}}
		
		
		
		
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Lancet}}
		
			9489
			
			,
	year={2005}
		
	

}

@incollection{b23,
	
	
		,
	title={{Biological correlates of blood pressure variability in elderly at high risk of cardiovascular disease}}
		,
	author={{
			RKPoortvliet
		} and {
			SMLloyd
		} and {
			IFord
		} and {
			NSattar
		} and {
			AJDe Craen
		} and {
			LWWijsman
		}}
		
		
		
		
		
	
	
		,
	journal={{Am J Hypertens}}
		
			28
			
			,
	year={2015}
		
	

}

@incollection{b24,
	
	
		,
	title={{Medical characteristics of the oldest old: retrospective chart review of patients aged 85+ in an academic primary care centre}}
		,
	author={{
			CSTsoi
		} and {
			JYChow
		} and {
			KSChoi
		}}
		
		
	
	
		,
	journal={{BMC Res Notes}}
		
			7
			340
			,
	year={2014}
		
	

}

@incollection{b25,
	
	
		,
	title={{Aggressive blood pressure lowering is dangerous: the J-curve: pro side of the argument}}
		,
	author={{
			GNMancia
		} and {
			GGrassi
		}}
		
	
	
		,
	journal={{Hypertension}}
		
			63
			
			,
	year={2014}
		
	

}

@incollection{b26,
	
	
		,
	title={{Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC)}}
		,
	author={{
			GMancia
		} and {
			RFagard
		} and {
			KNarkiewicz
		}}
		
		
	
	
		,
	journal={{J Hypertens}}
		
			31
			
			,
	year={2013}
		
	

}

@incollection{b27,
	
	
		,
	title={{Considerations for optimal blood pressure goals in the elderly population: a review of emergent evidence}}
		,
	author={{
			DXCao
		} and {
			RJTran
		}}
		
		10.1002/phar.2081
	
	
		,
	journal={{Pharmacotherapy}}
		
			,
	year={2018}
		
	
	,
	note={Epub ahead of print}

}

@incollection{b28,
	
	
		,
	title={{Blood pressure, antihypertensive polypharmacy, frailty, and risk for serious fall injuries among older treated adults with hypertension}}
		,
	author={{
			SGBromfield
		} and {
			CANgameni
		} and {
			LDColantonio
		}}
		
		
	
	
		,
	journal={{Hypertension}}
		
			70
			
			,
	year={2017}
		
	

}

@book{b29,
	
	
		,
	title={{Hypertension, its treatment, frailty, falls, and mortality}}
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	author={{
			MBurstyn
		}}
		
			,
	year={2017}
			70
			
		
	

}

@incollection{b30,
	
	
		,
	title={{Blood pressure and 10-year mortality risk in the Milan Geriatrics 75+ Cohort Study: role of functional and cognitive status}}
		,
	author={{
			GOgliare
		} and {
			RG JWestendorf
		} and {
			MMuller
		}}
		
		
	
	
		,
	journal={{Age and Ageing}}
		
			44
			
			,
	year={2015}
		
	

}

@incollection{b31,
	
	
		,
	title={{Arterial pressure, heart rate, and cerebral hemodynamics across the adult life span}}
		,
	author={{
			CYXing
		} and {
			TTarumi
		} and {
			RLMeijers
		}}
		
		
	
	
		,
	journal={{Hypertension}}
		
			69
			
			,
	year={2017}
		
	

}

@incollection{b32,
	
	
		,
	title={{Impaired dynamic cerebral autoregulation at rest and during isometric exercise in type 2 diabetes patients}}
		,
	author={{
			LCVianna
		} and {
			DeoS HJensen
		} and {
			AK
		}}
		
		
	
	
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	journal={{Am J Physiol Heart Circ Physiol}}
		
			308
			
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	year={2015}
		
	

}

@incollection{b33,
	
	
		,
	title={{Cerebral blood flow autoregulation in ischemic heart failure}}
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	author={{
			JRCaldas
		} and {
			RBPanerai
		} and {
			VJHaunton
		}}
		
		
	
	
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	journal={{Am J Physiol Regul Integr Comp Physiol}}
		
			312
			
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}

@incollection{b34,
	
	
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	title={{Cerebral autoregulation in orthostatic hypotension. A transcranial Doppler study}}
		,
	author={{
			ALagi
		} and {
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		} and {
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		}}
		
		
	
	
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			25
			
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}

@incollection{b35,
	
	
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	title={{Cerebral blood flow autoregulation in sepsis for the intensivist: why its monitoring may be the future of individualized care}}
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		} and {
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		} and {
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		}}
		
		
	
	
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			33
			
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}

@incollection{b36,
	
	
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	title={{Oral nifedipine in the treatment of hypertensive urgency: cerebrovascular accident following a single dose}}
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	author={{
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		} and {
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@incollection{b37,
	
	
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	title={{Cerebral hypoperfusion generates cortical watershed microinfarcts in Alzheimer disease}}
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			OCSuter
		} and {
			TSunthorn
		} and {
			RKraftsik
		}}
		
		
	
	
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	journal={{Stroke}}
		
			33
			
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}

@incollection{b38,
	
	
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	title={{Hypovolemiainduced severe coronary spasm leading to acute myocardial infarction}}
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		}}
		
		
	
	
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			17
			
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}

@incollection{b39,
	
	
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	title={{Consensus statement on the definition of orthostatic h ypotension, neurally mediated syncope and the postural tachycardia syndrome}}
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			21
			
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}

@incollection{b40,
	
	
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	title={{Measuring and defining orthostatic hypotension in the older person}}
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	author={{
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			SWParry
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	journal={{Age and Ageing}}
		
			43
			
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	year={2014}
		
	

}

@incollection{b41,
	
	
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	title={{Occurrence of hypotension in older participants. Which 24-hour ABPM parameter better correlate with?}}
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	author={{
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		} and {
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			67
			
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}

@incollection{b42,
	
	
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	title={{Autoregulation of cerebral blood flow in orthostatic hypotension}}
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@incollection{b43,
	
	
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	title={{Lack of orthostatic symptoms in de mentia patients with orthostatic hypotension}}
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}

@incollection{b45,
	
	
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	title={{Orthostatic hypotension predicts a poor prognosis in elderly people with dementia}}
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@incollection{b47,
	
	
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	title={{Orthostatic hypotension (OH) and mortality in relation to age, blood pressure and frailty}}
	
	
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			54
			
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}

@incollection{b48,
	
	
		,
	title={{Blood pressure, antihypertensive polypharmacy, frailty, and risk for serious fall injuries among older treated adults with hypertension}}
		,
	author={{
			SGBromfield
		} and {
			CANgameni
		} and {
			LDColantonio
		}}
		
		
	
	
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	journal={{Hypertension}}
		
			70
			
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	year={2017}
		
	

}

@book{b49,
	
	
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	title={{Postprandial hypotension: epidemiology, pathophysiology, and clinical management}}
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		Med1995
		
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@incollection{b50,
	
	
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	title={{High prevalence of postprandial and orthostatic hypotension among geriatric patients admitted to Dutch hospitals}}
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			REPel-Little
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			PAJansen
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			60
			
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}

@incollection{b51,
	
	
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	title={{Postprandial hypotension detected through home blood pressure monitoring: a frequent phenomenon in elderly hypertensive patients}}
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			37
			
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}

@incollection{b52,
	
	
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	title={{Assessment of orthostatic blood pressure. Measurement technique and clinical applications}}
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@incollection{b53,
	
	
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}

@incollection{b54,
	
	
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	title={{Orthostatic hypotension: is it a consistent finding?}}
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			162
			
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}

@incollection{b55,
	
	
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	title={{Postprandial hypotension: epidemiology, pathophysiology, and clinical management}}
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	title={{A global clinical measure of fitness and frailty in elderly people}}
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			XSong
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			CMacknight
		} and {
			HBergman
		} and {
			DBHogan
		} and {
			IMcdowell
		} and {
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		}}
		
		
		
		
		
		
	
	
		,
	journal={{CMAJ}}
		
			173
			
			,
	year={2005}
		
	

}

@incollection{b57,
	
	
		,
	title={{Cerebral blood flow autoregulation in sepsis for the intensivist: why its monitoring may be the future of individualized care}}
		,
	author={{
			CMGoodson
		} and {
			KRosenblatt
		} and {
			LRivera-Lara
		}}
		
		
	
	
		,
	journal={{J Intensive Care Med}}
		
			33
			
			,
	year={2018}
		
	

}

@incollection{b58,
	
	
		,
	title={{Neuro cardiovascular instability and cognition}}
		,
	author={{
			SO'callaghan
		} and {
			RAKenny
		}}
		
	
	
		,
	journal={{Yale J Biol Med}}
		
			89
			
			,
	year={2016}
		
	

}

@incollection{b59,
	
	
		,
	title={{Diagnosing orthostatic hypotension: a narrative review of the evidence}}
		,
	author={{
			JFrith
		}}
	
	
		,
	journal={{Brit Med Bull}}
		
			2015
			
		
	

}

@incollection{b60,
	
	
		,
	title={{Rates of deintensification of blood pressure and glycemic medication treatment based on levels of control and life expectancy in older patients with diabetes mellitus}}
		,
	author={{
			JBSussman
		} and {
			ERKerr
		} and {
			SDSaini
		}}
		
		
	
	
		,
	journal={{JAMA Intern Med}}
		
			174
			
			,
	year={2015}
		
	

}