@incollection{,
	
					
					
					E6B22FE6276B414EC1C2A78FFAE66B31
				,
	author={{MihikaShah} and {Mandar KalpeshShah} and {Sharan DharmeshShah} and {Harshil DevangPatel} and {Dr. MamtaGupta}},
	journal={{Global Journal of Medical Research}},
	journal={{GJMR}}2249-46180975-588810.34257/GJMR,
	address={Cambridge, United States},
	publisher={Global Journals Organisation}2017185
}

@book{b0,
	
	
		,
	title={{Vascular endothelial growth factor: basic science and clinical progress. Endocrine reviews}}
		,
	author={{
			NFerrara
		}}
		
			,
	year={2004 Aug 1}
			25
			
		
	

}

@incollection{b1,
	
	
		,
	title={{Tumor and hostmediated pathways of resistance and disease progression in response to antiangiogenic therapy}}
		,
	author={{
			JMEbos
		} and {
			CRLee
		} and {
			RSKerbel
		}}
		
		
	
	
		,
	journal={{Clinical Cancer Research}}
		
			15
			16
			
			,
	year={2009 Aug 15}
		
	

}

@incollection{b2,
	
	
		,
	title={{Risk of arterial thromboembolic events in patients with advanced colorectal cancer receiving bevacizumab}}
		,
	author={{
			NCTebbutt
		} and {
			FMurphy
		} and {
			DZannino
		} and {
			KWilson
		} and {
			MMCummins
		} and {
			EAbdi
		} and {
			AHStrickland
		} and {
			RMLowenthal
		} and {
			GMarx
		} and {
			CKarapetis
		} and {
			JShannon
		}}
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Annals of oncology}}
		
			22
			8
			
			,
	year={2011 Jan 27}
		
	

}

@incollection{b3,
	
	
		,
	title={{Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: a metaanalysis}}
		,
	author={{
			SRNalluri
		} and {
			DChu
		} and {
			RKeresztes
		} and {
			XZhu
		} and {
			SWu
		}}
		
		
		
		
	
	
		,
	journal={{Jama}}
		
			300
			19
			
			,
	year={2008 Nov 19}
		
	

}

@incollection{b4,
	
	
		,
	title={{PRISMA for Abstracts: Reporting Systematic Reviews in Journal and Conference Abstracts}}
		,
	author={{
			EMBeller
		} and {
			PPGlasziou
		} and {
			DGAltman
		}}
		
		
	
	
		,
	journal={{PLoS Med}}
		
			10
			4
			e1001419
			,
	year={2013}
		
	

}

@incollection{b5,
	
	
		,
	title={{Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: a randomized, double-blind, placebo-controlled phase III study}}
		,
	author={{
			AOhtsu
		} and {
			MAShah
		} and {
			EVan Cutsem
		} and {
			SYRha
		} and {
			ASawaki
		} and {
			SRPark
		} and {
			HYLim
		} and {
			YYamada
		} and {
			JWu
		} and {
			BLanger
		} and {
			MStarnawski
		}}
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{J Clin Oncol}}
		
			29
			30
			
			,
	year={2011 Oct 20}
		
	

}

@book{b6,
	
	
		,
	title={{Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. The Lancet}}
		,
	author={{
			BEscudier
		} and {
			APluzanska
		} and {
			PKoralewski
		} and {
			ARavaud
		} and {
			SBracarda
		} and {
			CSzczylik
		} and {
			CChevreau
		} and {
			MFilipek
		} and {
			BMelichar
		} and {
			EBajetta
		} and {
			VGorbunova
		}}
		
		
		
		
		
		
		
		
		
		
		
			,
	year={2007 Dec 22}
			370
			
		
	

}

@incollection{b7,
	
	
		,
	title={{OCEANS: a randomized, double-blind, placebocontrolled phase III trial of chemotherapy with or without bevacizumab in patients with platinumsensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancer}}
		,
	author={{
			CAghajanian
		} and {
			SVBlank
		} and {
			BAGoff
		} and {
			PLJudson
		} and {
			MGTeneriello
		} and {
			AHusain
		} and {
			MASovak
		} and {
			JYi
		} and {
			LRNycum
		}}
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Journal of clinical oncology}}
		
			30
			17
			2039
			,
	year={2012 Jun 10}
		
	

}

@incollection{b8,
	
	
		,
	title={{Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer}}
		,
	author={{
			DWMiles
		} and {
			AChan
		} and {
			LYDirix
		} and {
			JCortés
		} and {
			XPivot
		} and {
			PTomczak
		} and {
			TDelozier
		} and {
			JHSohn
		} and {
			LProvencher
		} and {
			FPuglisi
		} and {
			NHarbeck
		}}
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Journal of Clinical Oncology}}
		
			28
			20
			
			,
	year={2010 May 24}
		
	

}

@incollection{b9,
	
	
		,
	title={{Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer}}
		,
	author={{
			EVan Cutsem
		} and {
			WLVervenne
		} and {
			JBennouna
		} and {
			YHumblet
		} and {
			SGill
		} and {
			JLVan Laethem
		} and {
			CVerslype
		} and {
			WScheithauer
		} and {
			AShang
		} and {
			JCosaert
		} and {
			MJMoore
		}}
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Journal of clinical oncology}}
		
			27
			13
			
			,
	year={2009 Mar 23}
		
	

}

@incollection{b10,
	
	
		,
	title={{Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trial}}
		,
	author={{
			FFKabbinavar
		} and {
			JSchulz
		} and {
			MMccleod
		} and {
			TPatel
		} and {
			JTHamm
		} and {
			JRHecht
		} and {
			RMass
		} and {
			BPerrou
		} and {
			BNelson
		} and {
			WFNovotny
		}}
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Journal of Clinical Oncology}}
		
			23
			16
			
			,
	year={2005 Jun 1}
		
	

}

@incollection{b11,
	
	
		,
	title={{Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer}}
		,
	author={{
			HHurwitz
		} and {
			LFehrenbacher
		} and {
			WNovotny
		} and {
			TCartwright
		} and {
			JHainsworth
		} and {
			WHeim
		} and {
			JBerlin
		} and {
			ABaron
		} and {
			SGriffing
		} and {
			EHolmgren
		} and {
			NFerrara
		}}
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{New England journal of medicine}}
		
			350
			23
			
			,
	year={2004 Jun 3}
		
	

}

@incollection{b12,
	
	
		,
	title={{Bevacizumab in combination with fluorouracil and leucovorin: an active regimen for first-line metastatic colorectal cancer}}
		,
	author={{
			HIHurwitz
		} and {
			LFehrenbacher
		} and {
			JDHainsworth
		} and {
			WHeim
		} and {
			JBerlin
		} and {
			EHolmgren
		} and {
			JHambleton
		} and {
			WFNovotny
		} and {
			FKabbinavar
		}}
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Journal of Clinical Oncology}}
		
			23
			15
			
			,
	year={2005 May 20}
		
	

}

@book{b13,
	
	
		,
	title={{Efficacy and safety of bevacizumab in metastatic colorectal cancer: pooled analysis from seven randomized controlled trials. The oncologist}}
		,
	author={{
			HIHurwitz
		} and {
			NCTebbutt
		} and {
			FKabbinavar
		} and {
			BJGiantonio
		} and {
			ZZGuan
		} and {
			LMitchell
		} and {
			DWaterkamp
		} and {
			JTabernero
		}}
		
		
		
		
		
		
		
		
			,
	year={2013 Sep 1}
			18
			
		
	

}

@incollection{b14,
	
	
		,
	title={{Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAiL}}
		,
	author={{
			MReck
		} and {
			JPawel
		} and {
			PZatloukal
		} and {
			RRamlau
		} and {
			VGorbounova
		} and {
			VHirsh
		} and {
			NLeighl
		} and {
			JMezger
		} and {
			VArcher
		} and {
			NMoore
		} and {
			CManegold
		}}
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Journal of Clinical Oncology}}
		
			27
			8
			
			,
	year={2009 Feb 2}
		
	

}

@incollection{b15,
	
	
		,
	title={{RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer}}
		,
	author={{
			NJRobert
		} and {
			VDiéras
		} and {
			JGlaspy
		} and {
			AMBrufsky
		} and {
			IBondarenko
		} and {
			ONLipatov
		} and {
			EAPerez
		} and {
			YardleyDaChan
		} and {
			SYZhou
		} and {
			XPhan
		} and {
			SC
		}}
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Journal of clinical oncology}}
		
			29
			10
			
			,
	year={2011 Mar 7}
		
	

}

@incollection{b16,
	
	
		,
	title={{Incorporation of bevacizumab in the primary treatment of ovarian cancer}}
		,
	author={{
			RABurger
		} and {
			MFBrady
		} and {
			MABookman
		} and {
			GFFleming
		} and {
			BJMonk
		} and {
			HHuang
		} and {
			RSMannel
		} and {
			HDHomesley
		} and {
			JFowler
		} and {
			BEGreer
		} and {
			MBoente
		}}
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{New England Journal of Medicine}}
		
			365
			26
			
			,
	year={2011 Dec 29}
		
	

}

@incollection{b17,
	
	
		,
	title={{BEYOND: a randomized, double-blind, placebo-controlled, multicenter, phase III study of first-line carboplatin/paclitaxel plus bevacizumab or placebo in Chinese patients with advanced or recurrent nonsquamous non-small-cell lung cancer}}
		,
	author={{
			CZhou
		} and {
			YLWu
		} and {
			GChen
		} and {
			XLiu
		} and {
			YZhu
		} and {
			SLu
		} and {
			JFeng
		} and {
			JHe
		} and {
			BHan
		} and {
			JWang
		} and {
			GJiang
		}}
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Journal of Clinical Oncology}}
		
			33
			19
			
			,
	year={2015 May 26}
		
	

}

@incollection{b18,
	
	
		,
	title={{Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: phase III trial of the Cancer and Leukemia Group B (CALGB 80303)}}
		,
	author={{
			HLKindler
		} and {
			DNiedzwiecki
		} and {
			DHollis
		} and {
			SSutherland
		} and {
			DSchrag
		} and {
			HHurwitz
		} and {
			FInnocenti
		} and {
			MFMulcahy
		} and {
			EO'reilly
		} and {
			TFWozniak
		} and {
			JPicus
		}}
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Journal of Clinical Oncology}}
		
			28
			22
			3617
			,
	year={2010 Aug 1}
		
	

}

@incollection{b19,
	
	
		,
	title={{Multicenter, doubleblind, placebo-controlled, randomized phase II trial of gemcitabine/cisplatin plus bevacizumab or placebo in patients with malignant mesothelioma}}
		,
	author={{
			HLKindler
		} and {
			TGKarrison
		} and {
			DRGandara
		} and {
			CLu
		} and {
			LMKrug
		} and {
			JPStevenson
		} and {
			PAJänne
		} and {
			DIQuinn
		} and {
			MNKoczywas
		} and {
			JRBrahmer
		} and {
			KSAlbain
		}}
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Journal of Clinical Oncology}}
		
			30
			20
			2509
			,
	year={2012 Jul 10}
		
	

}

@incollection{b20,
	
	
		,
	title={{Bevacizumab, bleeding, thrombosis, and warfarin}}
		,
	author={{
			SKilickap
		} and {
			HAbali
		} and {
			ICelik
		}}
		
		
	
	
		,
	journal={{Journal of Clinical Oncology}}
		
			21
			18
			3542
			,
	year={2003 Sep 15}
		
	

}

@incollection{b21,
	
	
		,
	title={{Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor}}
		,
	author={{
			ZacharyI
		}}
	
	
		,
	journal={{American Journal of Physiology-Cell Physiology}}
		
			280
			6
			
			,
	year={2001 Jun 1}
		
	

}

@book{b22,
	
	
		,
	title={{VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis. Nature medicine}}
		,
	author={{
			BYTam
		} and {
			KWei
		} and {
			JSRudge
		} and {
			JHoffman
		} and {
			JHolash
		} and {
			SKPark
		} and {
			JYuan
		} and {
			CHefner
		} and {
			CChartier
		} and {
			JSLee
		} and {
			SJiang
		}}
		
		
		
		
		
		
		
		
		
		
		
			,
	year={2006 Jul}
			12
			793
		
	

}

@incollection{b23,
	
	
		,
	title={{Down syndrome critical region protein 1 (DSCR1), a novel VEGF target gene that regulates expression of inflammatory markers on activated endothelial cells}}
		,
	author={{
			BAHesser
		} and {
			XHLiang
		} and {
			GCamenisch
		} and {
			SYang
		} and {
			DALewin
		} and {
			RScheller
		} and {
			NFerrara
		} and {
			HPGerber
		}}
		
		
		
		
		
		
		
	
	
		,
	journal={{Blood}}
		
			104
			1
			
			,
	year={2004 Jul 1}
		
	

}

@book{b24,
	
	
		,
	title={{Analysis of coagulation cascade and endothelial cell activation during inhibition of vascular endothelial growth factor/vascular endothelial growth factor receptor pathway in cancer patients}}
		,
	author={{
			BCKuenen
		} and {
			MLevi
		} and {
			JCMeijers
		} and {
			AKKakkar
		} and {
			VWVan Hinsbergh
		} and {
			PJKostense
		} and {
			HMPinedo
		} and {
			KHoekman
		}}
		
		
		
		
		
		
		
		
	

}

@book{b25,
	
	
		,
	title={{}}
		,
	author={{
			ThrombosisArteriosclerosis
		}}
		
			,
	year={2002 Sep 1}
			22
			
		
	

}