# Introduction varian cysts are fluid-filled sacs in the ovary. They are common and usually form during ovulation. 1 Benign ovarian cysts are common in asymptomatic premenarchal girls and found in approximately 68% of ovaries of girls 2-12 years old and in 84% of ovaries of girls 0-2 years old. 2 Most of them are smaller than 9 mm while about 10-20% is larger macro cysts. While the smaller cysts mostly disappear within 6 months the larger ones appear to be more persistent. Only 8% of women present with symptom before menopause and 16% of women after menopause. The cysts are usually harmless. Patient usually present with complaints of abdominal pain, uterine bleeding, fullness, heaviness, pressure, swelling or bloating sensation abdomen. 3 Few patients may attend with sudden sharp pain abdomen. Sometimes patient comes with vague symptoms like frequent micturation, constipation, fatigue, headache, nausea, vomiting, weight gain etc. Patient of PCOS may present with increase facial hair, body hair, obesity andinfertility. 4 A Patient may present with complication like rupture and torsion of cyst, a ruptured ovarian cyst is usually selflimiting, and only requires keeping an eye on the situation and pain medications. The main symptom is abdominal pain, which may last a few days to several weeks, but they can also be asymptomatic. Rupture of large ovarian cysts can cause bleeding inside the abdominal cavity and in some cases shock. Cyst over then 4 cm diameter has increase risk (17%) of torsion followed by ischemic infarction. Definite diagnosis is made by histopathology. 5 Most cysts are functional (Follicular cyst, corpus lutium cyst) others are cystadenoma (serous cystadenoma, mucinous cystadenoma), dermoid cyst, andrometriosis, borderline tumor, chocolate cysts, hemorrhagic ovarian cysts, PCOS, ovarian cancer and simple squamous cyst. A total 95% of ovarian cysts are benign. Functional ovarian cysts and hemorrhagic ovarian cysts usually resolve spontaneously. 6 Cysts that persist beyond two or three menstrual cycles, or occur in post-menopausal women, may indicate more serious disease and should be investigated through ultrasonography and laparoscopy, especially in cases where family members have had ovarian cancer. # II. # Justification a) Objectives The objectives of the retrospective study to evaluate the basic knowledge about the ovarian tumors, clinical presentation and clinical assessment, outline the treatment of the ovarian tumors, about the histological of ovarian cancer, and follow up. # III. # Methods # a) Study design This retrospective study is conducted in Apollo Hospital Dhaka, Bangladesh during the period of one year six months. This analysis was done keeping in mind the objectives to know the clinical symptoms, treatment and histopathology of patients who required the surgery for ovarian cyst. We have operated most of the case, laproscopically; however few patients who had large mass and unfit for laparoscopic surgery underwent conventional laparotomy. Indication for surgery were large mass >6 cm, mass with symptoms and solid components, persisting ovarian cyst <6 cm even after 3 months of oral contraceptive treatment, acute symptoms suggestive of torsion. All elective cases were done after routine investigations, anesthetic check-up and with valid consent after explaining procedure and complications of the surgery (laparoscopy / laparotomy). CA-125 was not done routinely for all patients except for few patients who were more than 40 years or any high risk for malignancy. The decision for cystectomy or ovariotomy was taken on the operation table. Specimen was retrieved by colpotomy or through the side port of laparoscopy. All the tissues were sent for histopathology analysis on the day of the surgery. Our patients were discharged 48hrs after laparoscopic surgery and after 7 days after laparotomy. All patients were followed up after 2 week with histopathologic report, retrospectively all the clinical symptoms, and histopathology reports are analyzed to know the fact whether really, these patients required the surgery. # b) Study Area, Duration This study was conducted in Gynae & Obst Department of Apollo Hospital Dhaka, Bangladesh during the period from January 2019 to April 2020. # c) Population A total 250 subjects were enrolled in this study. # Inclusion criteria Simple or endometriotic ovarian cysts (3.0-10.6 cm) at ultrasonic examinations. At USG, a simple cyst was defined as a cyst with no papillary projections, a clearly defined wall, and clear content. Although color Doppler US was used in many cases to examine the neovascularity of the cyst, specific Doppler studies were not done routinely in every patient. # Exclusion criteria 1. Evidence of renal or hepatic disease. 2. An abnormal value (>35 IU/mL) of serum CA-125 . 3. Patient with adnexal mass. # d) Methods of data collection Data was collected from computerized data base using a questionnaire made specifically for the manner of the research and the data was next analyzed by using SPSS program. Variables included age in years, married or not, parity, height in cm, weight, BMI, and pregnant or not. Clinical presentation abdominal pain or otherwise, number of cysts, location and type of cysts was also included. # e) Ethical Clearance This study was approved by the Ethical committee of the hospital. # IV. # Results A total of 250 cases of ovarian cysts were included. The mean ± standard deviation [SD] age of these patients was 35.36±15.849 years. The mean±SD parity was 2.20±2.675. The height ranged was from 128-180 cm with a mean±SD of 150.88±16.227. The weight ranged from 35-92 kg with a mean±SD of 65.58±22.506. The calculated BMI ranged from 15-47 with a mean±SD of 27.76±6.314. Out of 250 patients diagnosed with ovarian cysts, 165 were married (66%), and of those only 16 were pregnant (6.4%). (Table 1) Only 59 (47.96%) patients were benign cystic ovarian tumors, of which 47 (18.8%), cases were serous cystadenoma which was the commonest of all in this study. This was followed by mucinous cystadenoma 24 (9.6%).In our study the least common benign tumor was serous fibroadenoma, which was seen in 4 (1.6%). We came across only two (0.8%) case of malignant ovarian tumor, which was found in a postmenopausal woman. Border malignancies were encountered in 8 patients (3.2%), of which 4 were border line papillary serous tumor and 4 were of border line mucinous tumor. In our study there were 62 cases of functional cysts, of which 41 (16.4%) were Simple follicular cysts and 22 (8.8%) corpus luteum cysts. Majority of these cases responded for the three months of cyclical oral contraceptive pills. The patients with no response were subjected for the laparoscopy, which were turned to be cases of either paraovarian or endometriotic cysts. Among these tumors 4 cases were para ovarian cysts and 33 (13.2%) endometriotic cysts (Table 2). # Table 2: Incidence of ovarian cysts and tumors Majority of the patients had presented with pain abdomen, which was vague and associated with a feeling of heaviness in the lower abdomen. However, six (2.43%) patients had presented with severe pain abdomen and there were signs of acute abdomen. These patients were clinically suspected to have twisted ovarian cysts. A diagnosis was confirmed by Ultrasonography and Doppler study. In the reproductive age group 24 (9.75%) cases had presented with menorrhagia and dysmenorrhea. Only five were diagnosed as cystic ovarian lesion by clinical examination. However, all were diagnosed by Ultrasonography. Only 14 ( The age of the patients in our study ranged from 16yrs to 70 yrs. The maximum number of cystic ovarian tumors occurred in the age group of 20 to 29 are 44.18% (patient-108) and in the age group 30 to 39 are 33.33% (patient 82). The total numbers of cases in the age group 16 to 39 years were 200 (77.51%). The youngest patient was aged 16 years with mature cystic teratoma and the oldest patient was aged 64 years, with borderline papillary serous tumor. The two who have serous cyst adenocarcinoma was aged 60 to 69 group (Table 5). # Table 5: Age wise distribution of ovarian tumors # Discussion Cystic ovarian masses or ovarian tumors are common problem encountered by women and they present with vague symptoms. The lesions are either physiological, or pathological. They can occur as functional cysts, benign or malignant tumors. It is very essential to differentiate as it requires executing a definitive treatment. As the symptoms are being vague, in making the definitive diagnosis, it is advised to take the combination of clinical examination, Ultrasonography and tumor marker CA 125 levels to arrive at proper diagnosis. However, histopathology gives the final diagnosis. Malignancy is usually less in ovary as the ovary is a partially cystic organ. Ovarian malignancy is rarely seen in the age group of 15-40 years. 7 The functional, nonneoplastic and benign cystic ovarian lesions are common in the younger age. However, the chance of malignancy increases as the age advances. 8 Functional ovarian cysts, which are unilocular usually resolve spontaneously. 9 Oral contraceptives, over a period of 3 to 6 months, also resolves the functional ovarian cysts, this also helps to distinguish a physiological ovarian cyst from a pathological one. 10 A simple, unilocular cystic ovarian lesion, can be monitored with serial ultra-sonography and CA 125, for its resolution over a period of time and unnecessary excision avoided. A unilocular echo free ovarian cyst, to be malignant, is less than 1.6%. 11 This descriptive study was undertaken, to analyse and correlate the histopathological diagnosis with the, clinical presentations, age factors and ultra-sound findings of the 250 cases of cystic ovarian masses, during the study period. # Article Reviewed In our study, abdominal pain was the commonest symptom, 168 (67.2%) cases; same incidence was reported by Kayastha. 12 In their study the incidence of benign cystic ovarian tumors was 59 (47.9%). The benign epithelial was 37 (62.71%) cases. The benign germ cell tumor-mature cystic teratoma was 22 (37.3%). In our study benign cystic ovarian tumor was the commonest, the age incidence was 20 to 49 years, and pain abdomen was the commonest symptom. Similar findings were reported by Pilli and suneeta. 13 Among the benign epithelial tumors, serous cystadenoma were 23 (38.98%). mucinous cystadenoma were 12 (20.34%) and serous fibroadenoma were 2 (3.39%). Bhattachery et al reported benign epithelial tumors (61.60%) and mature cystic teratoma (24.8%). 14 Gupta et al reported the incidence of benign epithelial tumors as (48.8%) and mature cystic teratoma as (23.9%). Mondal et al reported, serous cystadenoma (29.9%) mucinous cystadenoma (11.1%) and mature cystic teratoma (15.9%). 15 In our study also, benign epithelial tumors are more common and there is a preponderance of serous cystadenoma over mucinous cystadenoma. Maliheh et al reported, that the commonest benign ovarian tumor was serous cystadenoma (38%) followed by mature cysticteratoma (30%), mucinous cystadenoma (22%), Yasmin et al reported serous cystadenoma (24%) and mature cysticteratoma (18%). 15 Non-neoplastic cystic ovarian tumors in our study were 108 (43.2%), of which simple follicular cyst were 41 cases and Corpus luteum cysts 22 cases. The endometriotic cysts in our study were 33 (13.2%). Maliheh reported Functional cysts as (57.54%) and endometriotic cysts as (5.9%). Cohen et al reported that ovarian endometriosis is common. 16 Serous cyst adenocarcinoma was the malignant ovarian tumor in our study, two cases (0.8%). There were 4 (1.6%) cases of borderline serous papillary tumor and 4 (1.6%) cases of borderline mucinous tumor, in our study, Same findings were reported by Mondal et al and Bhattachery et al that epithelial malignant tumors are the commonest. DeKroon et al reported that ultrasonography diagnosed Mature Cystic teratoma accurately. 17 In our study all of 45 cases of mature cystic teratoma were diagnosed by ultrasonography. # VI. # Conclusion Simple ovarian cysts, unilocular in nature, are usually functional ovarian cysts and resolve spontaneously. If not resolve spontaneously, 3 to 6 months of oral contraceptives, usually resolves them and this also helps to distinguish between physiological and pathological ovarian cysts. Benign ovarian tumors exhibit a wide range of clinical symptoms. Pain abdomen is the commonest symptom in cystic ovarian tumors. Ultrasonography accurately diagnosis mature cystic teratoma Decision of surgical intervention depends on size of cysts, histopathological finding. Epithelial tumors are commonest of the benign ovarian tumors. # Funding: No funding sources Conflict of interest: None declared. 1Year 202022 3Forty (16.26%) patients were found to havewas diagnosed by ultra-sonography as cystic ovariancystic ovarian masses incidentally by Ultrasonography,lesion with hyperechoic areas and calcification. Theof which 24 cases were investigated for infertility. Matureserous cystadenoma were reported as, anechoic cystscystic teratoma, which numbered 44 cases (17.89%),in 22 cases, anechoic cyst with septa in 10 cases and 4Year 202024 © 2020 Global Journals * Office on Women's Health November 19. 2014. June 2015. 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