@incollection{,
	
					
					
					B5A5E1DC128A2EEF187CC115B780C3AD
				,
	author={{Josenel Maria Barcelos Marçal, Júlia Iaroseski, Luiz Fillipe Pinto da Silva, Thales Augusto Della Torre Marzarotto, Giulia Righetti Tuppini Vargas, Vitória Morita Fukuoka, Luiza Carolina da Rosa Scherner, Rafael Fabiano Machado Rosa, Paulo Ricardo GazzolaZen} and {Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA)}},
	journal={{Global Journal of Medical Research}},
	journal={{GJMR}}2249-46180975-588810.34257/GJMR,
	address={Cambridge, United States},
	publisher={Global Journals Organisation}21119
}

@incollection{b0,
	
	
		,
	title={{VEGF in signaling and disease: beyond discovery and development}}
		,
	author={{
			RSApte
		} and {
			DSChen
		} and {
			NFerrara
		}}
		
		
		10.1016/j.cell.2019.01.02
	
	
		,
	journal={{Cell}}
		
			176
			
			,
	year={2019}
		
	

}

@incollection{b1,
	
	
		,
	title={{Macrophageepithelial interactions in pulmonary alveoli}}
		,
	author={{
			JBhattacharya
		} and {
			KWestphalen
		}}
		
		doi:10.1007/s 00281-016-0569-x
	
	
		,
	journal={{Semin. Immunopathol}}
		
			38
			
			,
	year={2016}
		
	

}

@incollection{b2,
	
	
		,
	title={{Genome-wide transcriptional profiling reveals connective tissue mast cell accumulation in bronchopulmonary dysplasia}}
		,
	author={{
			SBhattacharya
		} and {
			DGo
		} and {
			DLKrenitsky
		} and {
			HLHuyck
		} and {
			SKSolleti
		} and {
			VALunger
		} and {
			LMetlay
		} and {
			SSrisuma
		} and {
			SEWert
		} and {
			TJMariani
		}}
		
		
		
		
		
		
		
		
		
		10.1164/rccm.201203-0406OC
	
	
		,
	journal={{Am. J. Respir. Crit. Care Med}}
		
			186
			
			,
	year={2012}
		
	

}

@incollection{b3,
	
	
		,
	title={{Type 2 alveolar cells are stem cells in adult lung}}
		,
	author={{
			CEBarkauskas
		} and {
			MJCronce
		} and {
			CRRackley
		} and {
			EJBowie
		} and {
			DRKeene
		} and {
			BRStripp
		} and {
			SHRandell
		} and {
			PWNoble
		} and {
			BLHogan
		}}
		
		
		
		
		
		
		
		
	
	
		,
	journal={{J. Clin. Invest}}
		
			123
			
			,
	year={2013}
		
	

}

@incollection{b4,
	
	
		,
	title={{Efficient estimation of the total number of acini in adult rat lung}}
		,
	author={{
			SFBarre
		} and {
			DHaberthur
		} and {
			MStampanoni
		} and {
			JCSchittny
		}}
		
		
		
		10.14814/phy2.12063
	
	
		,
	journal={{Physiol Rep}}
		
			2
			,
	year={2014}
		
	

}

@incollection{b5,
	
	
		,
	title={{Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia}}
		,
	author={{
			HBenlhabib
		} and {
			CRMendelson
		}}
		
	
	
		,
	journal={{Mol. Cell. Biol}}
		
			31
			
		
	

}

@incollection{b6,
	
	
		,
	title={{Concerted gene duplications in the two keratin gene families}}
		,
	author={{
			MBlumenberg
		}}
	
	
		,
	journal={{J Mol Evol}}
		
			27
			3
			
			,
	year={1998}
		
	

}

@incollection{b7,
	
	
		,
	title={{Fetal breathing movements and changes at birth}}
		,
	author={{
			BJKoos
		} and {
			ARajaee
		}}
		
		10.1007/978-1-4939-1031-1_8
	
	
		,
	journal={{Adv Exp Med Biol}}
		
			814
			
			,
	year={2014}
		
	

}

@incollection{b8,
	
	
		,
	title={{Molecular regulation of lung development}}
		,
	author={{
			WVCardoso
		}}
	
	
		,
	journal={{Annu Rev Physiol}}
		
			63
			
			,
	year={2001}
		
	

}

@book{b9,
	
	
		,
	title={{Identification of bronchioalveolar stem cells in normal lung and lung. cancerCell}}
		,
	author={{
			WVCardoso
		} and {
			J. ; F-Carla F BenderLu
		} and {
			EricaLKim
		} and {
			AmberEJackson
		} and {
			SharonWoolfenden
		} and {
			ImranLawrence
		} and {
			SinaeBabar
		} and {
			DeniseVogel
		} and {
			Crowley
		} and {
			TRoderick
		} and {
			TylerBronson
		} and {
			Jacks
		}}
		
		
		
		
		
		
		
		
		
		
		
		
			,
	year={2006. 2005 Jun 17}
			121
			
		
	
	,
	note={Regulation of early lung morphogenesis: questions}

}

@book{b10,
	
	
		,
	title={{Identification of bronchioalveolar stem cells in normal lung and lung cancer Cell}}
		,
	author={{
			Carla F BenderKim
		} and {
			EricaLJackson
		} and {
			AmberEWoolfenden
		} and {
			SharonLawrence
		} and {
			ImranBabar
		} and {
			SinaeVogel
		} and {
			DeniseCrowley
		} and {
			TRoderick
		} and {
			TylerBronson
		} and {
			Jacks
		}}
		
		
		
		
		
		
		
		
		
		
			,
	year={2005 Jun 17}
			121
			
		
	

}

@incollection{b11,
	
	
		,
	title={{Developmental pathways in the pathogenesis of lung fibrosis}}
		,
	author={{
			DChanda
		} and {
			EOtoupalova
		} and {
			SRSmith
		} and {
			TVolckaert
		} and {
			SPDe Langhe
		} and {
			VJThannickal
		}}
		
		
		
		
		
		doi:10.1016/ j.mam.2018.08.004
	
	
		,
	journal={{Mol Aspects Med}}
		
			65
			
			,
	year={2019}
		
	

}

@incollection{b12,
	
	
		,
	title={{Developmental and pathological angiogenesis}}
		,
	author={{
			ASChung
		} and {
			NFerrara
		}}
		
		10.1146/annurev-cellbio-092910-154002
	
	
		,
	journal={{Annu. Rev. Cell Dev. Biol}}
		
			22011
			
		
	

}

@incollection{b13,
	
	
		,
	title={{Sleep effects on breathing and respiratory diseases}}
		,
	author={{
			SSChoudhary
		} and {
			SRChoudhary
		}}
		
		10.4103/0970-2113.56345
		20531993
	
	
		,
	journal={{Lung India}}
		
			26
			4
			
			,
	year={2009 Oct}
		
	

}

@book{b14,
	
	
		,
	title={{Transcription factors in mouse lung development and function}}
		,
	author={{
			RHCosta
		} and {
			VVKalinichenko
		} and {
			LLim
		}}
		
		
		
	

}

@incollection{b15,
	
	
		,
	title={{}}
	
	
		,
	journal={{Am J Physiol Lung Cell Mol Physiol}}
		
			280
			
			,
	year={2001}
		
	

}

@incollection{b16,
	
	
		,
	title={{Endothelial Sash1 is required for lung maturation through nitric oxide signaling}}
		,
	author={{
			PCoulombe
		} and {
			GNPaliouras
		} and {
			AClayton
		} and {
			AHussainkhel
		} and {
			MFuller
		} and {
			VJovanovic
		}}
		
		
		
		
		
		10.1016/j.celrep.2019.04.03
	
	
		,
	journal={{Cell Rep}}
		
			27
			
			,
	year={2019}
		
	

}

@incollection{b17,
	
	
		,
	title={{Morphologic changes in pulmonary oxygen toxicity}}
		,
	author={{
			JDCrapo
		}}
	
	
		,
	journal={{Annu Rev Physiol}}
		
			48
			
			,
	year={1986}
		
	

}

@incollection{b18,
	
	
		,
	title={{The epigenetic regulation of miR-1792 contributes to the pathogenesis of pulmonary fibrosis}}
		,
	author={{
			DDakhlallah
		} and {
			KBatte
		} and {
			YWang
		} and {
			CZCantemir-Stone
		} and {
			PYan
		} and {
			GNuovo
		} and {
			AMikhail
		} and {
			CLHitchcock
		} and {
			VPWright
		} and {
			SPNana-Sinkam
		}}
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Breathe. Care Med}}
		
			187
			
			,
	year={2013}
		
	

}

@incollection{b19,
	
	
		,
	title={{Alveolar progenitor and stem cells in lung development, renewaand cancer}}
		,
	author={{
			TJDesai
		} and {
			DGBrownfield
		} and {
			MAKrasnow
		}}
		
		
		10.1038/nature12930
	
	
		,
	journal={{Nature}}
		
			507
			
			,
	year={2014}
		
	

}

@incollection{b20,
	
	
		,
	title={{Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization}}
		,
	author={{
			BSDing
		} and {
			DJNolan
		} and {
			PGuo
		} and {
			AOBabazadeh
		} and {
			ZCao
		} and {
			ZRosenwaks
		} and {
			RGCrystal
		} and {
			MSimons
		} and {
			TNSato
		} and {
			SWorgall
		} and {
			KShido
		} and {
			SYRabbany
		} and {
			SRafii
		}}
		
		
		
		
		
		
		
		
		
		
		
		
		10.1016/j.cell.2011.10.003
	
	
		,
	journal={{Cell}}
		
			147
			3
			
			,
	year={2011 Oct 28}
		
	

}

@incollection{b21,
	
	
		,
	title={{Identification and expansion of the tumorigenic lung cancer stem cell population}}
		,
	author={{
			AEramo
		} and {
			FLotti
		} and {
			GSette
		} and {
			EPilozzi
		} and {
			MBiffoni
		} and {
			DiVirgilio
		} and {
			AConticello
		} and {
			CRuco
		} and {
			LPeschle
		} and {
			C
		} and {
			DeMaria
		} and {
			R
		}}
		
		
		
		
		
		
		
		
		
		
		
		10.1038/sj.cdd.4402283
		18049477
	
	
		,
	journal={{Cell Death Differ}}
		
			15
			3
			
			,
	year={2008 Mar. 2007 Nov 30}
		
	

}

@book{b22,
	
	
		,
	title={{Borderline Dravet syndrome: a useful diagnostic category? Epilepsia}}
		,
	author={{
			RGuerrini
		} and {
			HOguni
		}}
		
		10.1111/j.1528-1167.2011.02995.x
		21463273
		
			,
	year={2011 Apr}
			52
			
		
	
	,
	note={Suppl}

}

@book{b23,
	
	
		,
	title={{Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways}}
		,
	author={{
			AGuha
		} and {
			MVasconcelos
		} and {
			YCai
		} and {
			MYoneda
		} and {
			AHinds
		} and {
			JQian
		} and {
			GLi
		} and {
			LDickel
		} and {
			JEJohnson
		} and {
			SKimura
		} and {
			JGuo
		} and {
			JMcmahon
		} and {
			APMcmahon
		} and {
			WVCardoso
		}}
		
		
		
		
		
		
		
		
		
		
		
		
		
		10.1073/pnas.1204710109
		
		
			,
	year={2012}
			109
			
		
		
			Proceedings of the National Academy of Sciences of the United States of America
		
	

}

@incollection{b24,
	
	
		,
	title={{Tissue crosstalk in lung development}}
		,
	author={{
			EAHines
		} and {
			XSun
		}}
		
	
	
		,
	journal={{J. Cell. Biochem}}
		
			115
			
			,
	year={2014}
		
	

}

@incollection{b25,
	
	
		,
	title={{Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function}}
		,
	author={{
			BL MHogan
		} and {
			CEBarkauskas
		} and {
			HAChapman
		} and {
			JAEpstein
		} and {
			RJain
		} and {
			CC WHsia
		} and {
			LNiklason
		} and {
			ECalle
		} and {
			ALe
		} and {
			SHRandell
		}}
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Cell Stem Cell}}
		
			15
			
			,
	year={2014}
		
	

}

@incollection{b26,
	
	
		,
	title={{Clara cell secretory proteinexpressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion}}
		,
	author={{
			KUHong
		} and {
			SDReynolds
		} and {
			AGiangreco
		} and {
			CMHurley
		} and {
			BRStripp
		}}
		
		
		
		
	
	
		,
	journal={{Am. J. Respir. Cell Mol. Biol}}
		
			24
			
			,
	year={2001}
		
	

}

@incollection{b27,
	
	
		,
	title={{Clara cell secretory proteinexpressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion}}
		,
	author={{
			KUHong
		} and {
			SDReynolds
		} and {
			AGiangreco
		} and {
			CMHurley
		} and {
			BRStripp
		}}
		
		
		
		
		10.1165/ajrcmb.24.6.4498
		
	
	
		,
	journal={{Am. J. Respir. Cell Mol. Biol}}
		
			24
			
			,
	year={2001}
		
	

}

@incollection{b28,
	
	
		,
	title={{Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium}}
		,
	author={{
			KUHong
		} and {
			SDReynolds
		} and {
			SWatkins
		} and {
			EFuchs
		} and {
			BRStripp
		}}
		
		
		
		
	
	
		,
	journal={{Am. J. Pathol}}
		
			164
			
			,
	year={2004}
		
	

}

@book{b29,
	
	
		,
	title={{Population in Human Lung Cancer Cell Lines and Tumors Is Enriched with Stem-like Cancer Cells.Cancer Res}}
		,
	author={{
			MMHo
		}}
		10.1158/0008-5472.CAN-06-3557oi:10.1016/j.stem.2014.07.012
		
			,
	year={May 15 2007}
			
		
	

}

@incollection{b30,
	
	
		,
	title={{COPD as a disease of accelerated lung aging}}
		,
	author={{
			KIto
		} and {
			PJBarnes
		}}
		
		10.1378/chest.08-1419
	
	
		,
	journal={{Chest}}
		
			135
			
			,
	year={2009}
		
	

}

@incollection{b31,
	
	
		,
	title={{Partial pneumonectomy of telomerase null mice carrying shortened telomeres initiates cell growth arrest resulting in a limited compensatory growth response}}
		,
	author={{
			SRJackson
		} and {
			JLee
		} and {
			RReddy
		} and {
			GNWilliams
		} and {
			AKikuchi
		} and {
			YFreiberg
		} and {
			DWarburton
		} and {
			BDriscoll
		}}
		
		
		
		
		
		
		
	
	
		,
	journal={{Am J Physiol Lung Cell Mol Physiol}}
		
			300
			
			,
	year={2011}
		
	

}

@incollection{b32,
	
	
		,
	title={{Physiological changes in respiratory function associated with ageing}}
		,
	author={{
			JPJanssens
		} and {
			JCPache
		} and {
			LPNicod
		}}
		
		
	
	
		,
	journal={{Eur Respir J}}
		
			13
			
			,
	year={1999}
		
	

}

@incollection{b33,
	
	
		,
	title={{Vascular endothelial growth factor signaling in development and disease}}
		,
	author={{
			SKaraman
		} and {
			VMLeppanen
		} and {
			Alitalo
		} and {
			K
		}}
		
		
		
		10.1242/dev.151019
	
	
		,
	journal={{Development}}
		
			145
			151019
			,
	year={2018}
		
	

}

@incollection{b34,
	
	
		,
	title={{Identification of bronchioalveolar stem cells in normal lung and lung cancer}}
		,
	author={{
			CFKim
		} and {
			ELJackson
		} and {
			AEWoolfenden
		} and {
			SLawrence
		} and {
			IBabar
		} and {
			SVogel
		} and {
			DCrowley
		} and {
			RTBronson
		} and {
			TJacks
		}}
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Cell}}
		
			121
			
			,
	year={2005}
		
	

}

@incollection{b35,
	
	
		,
	title={{Fetal breathing movements and changes at birth}}
		,
	author={{
			BJKoos
		} and {
			ARajaee
		}}
		
		10.1007/978-1-4939-1031-1_8
	
	
		,
	journal={{Adv Exp Med Biol}}
		
			814
			
			,
	year={2014}
		
	

}

@incollection{b36,
	
	
		,
	title={{The association between baseline clinical-radiological characteristics and growth of pulmonary nodules with ground-glass opacity}}
		,
	author={{
			YKobayashi
		} and {
			YSakao
		} and {
			GADeshpande
		}}
		
		
	
	
		,
	journal={{Lung Cancer}}
		
			83
			
			,
	year={2014}
		
	

}

@incollection{b37,
	
	
		,
	title={{Analysis of epidermal growth factor receptor gene mutation in patients with non-small cell lung cancer and acquired resistance to gefitinib}}
		,
	author={{
			TKosaka
		} and {
			YYatabe
		} and {
			HEndoh
		}}
		
		
	
	
		,
	journal={{Clin Cancer Res}}
		
			12
			
			,
	year={2006}
		
	

}

@incollection{b38,
	
	
		,
	title={{Lung regeneration: mechanisms, applications and emerging stem cell populations}}
		,
	author={{
			DNKotton
		} and {
			EEMorrisey
		}}
		
		10.1038/nm.3642
	
	
		,
	journal={{Nat. Med}}
		
			20
			
			,
	year={2014}
		
	

}

@incollection{b39,
	
	
		,
	title={{Formação de um órgão neurossensorial por deslizamento de células epiteliais}}
		,
	author={{
			CSKuo
		} and {
			MAKrasnow
		}}
		
	
	
		,
	journal={{Célula}}
		
			163
			
			,
	year={2015}
		
	

}

@incollection{b40,
	
	
		,
	title={{A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration}}
		,
	author={{
			YZhang
		} and {
			AMGoss
		} and {
			EDCohen
		} and {
			RKadzik
		} and {
			JJLepore
		} and {
			KMuthukumaraswamy
		} and {
			JYang
		} and {
			FJDemayo
		} and {
			JAWhitsett
		} and {
			MSParmacek
		} and {
			EEMorrisey
		}}
		
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Nature Genetics}}
		
			40
			
			,
	year={2008}
		
	

}

@incollection{b41,
	
	
		,
	title={{Wnt5a participates in distal lung morphogenesis}}
		,
	author={{
			CLi
		} and {
			JXiao
		} and {
			KHormi
		} and {
			ZBorok
		} and {
			PMinoo
		}}
		
		
		
		
		10.1006/dbio.2002.0729
	
	
		,
	journal={{Dev. Biol}}
		
			2020
			
		
	

}

@book{b42,
	
	
		,
	author={{
			CLi
		} and {
			LHu
		} and {
			JXiao
		} and {
			HChen
		} and {
			JTLi
		} and {
			SBellusci
		} and {
			SDelanghe
		} and {
			PMinoo
		}}
		
		
		
		
		
		
		
		,
	title={{Wnt5a regulates Shh and Fgf10 signaling during lung development. Dev}}
				
	

}

@incollection{b43,
	
	
		,
	title={{}}
		10.1016/j.ydbio.2005.08.035
	
	
		,
	journal={{Biol}}
		
			287
			
			,
	year={2005}
		
	

}

@incollection{b44,
	
	
		,
	title={{The strength of mechanical forces determines the differentiation of alveolar epithelial cells}}
		,
	author={{
			JLi
		} and {
			ZWang
		} and {
			QChu
		} and {
			KJiang
		} and {
			JLi
		} and {
			NTang
		}}
		
		
		
		
		
		e5.10.1016/j.devcel.2018.01.008
	
	
		,
	journal={{Dev. Cell}}
		
			44
			
			,
	year={2018}
		
	

}

@book{b45,
	
	
		,
	title={{FGF receptors control alveolar elastogenesis}}
		,
	author={{
			RLi
		} and {
			JCHerriges
		} and {
			LChen
		} and {
			RPMecham
		} and {
			XSun
		}}
		
		
		
		
		10.1242/dev.149443
		
			,
	year={2017}
			144
			
		
	

}

@incollection{b46,
	
	
		,
	title={{Airway glandular development and stem cells}}
		,
	author={{
			XLiu
		} and {
			RRDriskell
		} and {
			JFEngelhardt
		}}
		
		
		10.1016/S0070-2153(04
	
	
		,
	journal={{Curr. Top. Dev. Biol}}
		
			64
			
			,
	year={2004}
		
	

}

@book{b47,
	
	
		,
	title={{The immunogenicity and immune tolerance of pluripotent stem cell derivatives. Front Immunol}}
		,
	author={{
			XLiu
		} and {
			WLi
		} and {
			XFu
		} and {
			YXu
		}}
		
		
		
		10.3389/fimmu.2017.0064
		
			,
	year={2017}
			8
		
	

}

@incollection{b48,
	
	
		,
	title={{Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung}}
		,
	author={{
			JLMcqualter
		} and {
			KYuen
		} and {
			BWilliams
		} and {
			IBertoncello
		}}
		
		
		
		doi: 10.1073/ pnas.0909207107
	
	
		,
	journal={{Proc Natl Acad Sci U S A}}
		
			107
			
			,
	year={2010}
		
	

}

@incollection{b49,
	
	
		,
	title={{Transcriptional regulation of the surfactant protein-A gene in fetal lung}}
		,
	author={{
			CRMendelson
		} and {
			EGao
		} and {
			PPYoung
		} and {
			LFMichael
		} and {
			JLAlcorn
		}}
		
		
		
		
		10.1378/chest.111.6_Supplement.96S-
		
	
	
		,
	journal={{Chest}}
		
			111
			
			,
	year={1997}
		
	

}

@incollection{b50,
	
	
		,
	title={{The human keratins: biology and pathology}}
		,
	author={{
			RMoll
		} and {
			MDivo
		} and {
			LLangbein
		}}
		
		
		10.1007/s00418-008-0435-6
	
	
		,
	journal={{Histochem Cell Biol}}
		
			129
			6
			
			,
	year={2008}
		
	

}

@incollection{b51,
	
	
		,
	title={{Preparing for the first breath: genetic and cellular mechanisms in lung development}}
		,
	author={{
			EEMorrisey
		} and {
			BLHogan
		}}
		
		10.1016/j.devcel.2009.12.010
		
	
	
		,
	journal={{Dev. Cel}}
		
			18
			,
	year={2010}
		
	

}

@book{b52,
	
	
		,
	title={{Molecular determinants of lung development}}
		,
	author={{
			EEMorrisey
		} and {
			WVCardoso
		} and {
			RHLane
		} and {
			MRabinovitch
		} and {
			SHAbman
		} and {
			AiXAlbertine
		} and {
			KHBland
		} and {
			RDChapman
		} and {
			HACheckley
		} and {
			WEpstein
		} and {
			JAKintner
		} and {
			CRKumar
		} and {
			MMinoo
		} and {
			PMariani
		} and {
			TJMcdonald
		} and {
			DMMukouyama
		} and {
			YSPrince
		} and {
			LSReese
		} and {
			JRossant
		} and {
			JShi
		} and {
			WSun
		} and {
			XWerb
		} and {
			ZWhitsett
		} and {
			JAGail
		} and {
			DBlaisdell
		} and {
			CJLin
		} and {
			QS
		}}
		
		
		
		
		
		
		
		
		
		
		
		
		
		
		
		
		
		
		
		
		
		
		
		
		
		
		
			,
	year={2013}
			,
	publisher={Ann Am Thorac Soc}
			10
			
		
	

}

@incollection{b53,
	
	
		,
	title={{Regeneration of the Aging Lung: A Mini-Review}}
		,
	author={{
			SNavarro
		} and {
			BDriscoll
		}}
		
		10.1159/000451081
		27825158
	
	
		,
	journal={{Gerontology}}
		
			63
			3
			
			,
	year={2017. 2016 Nov 9}
		
	

}

@incollection{b54,
	
	
		,
	title={{Human lung development: recent progress and new challenges}}
		,
	author={{
			MZNikolic
		} and {
			DSun
		} and {
			ELRawlins
		}}
		
		
	
	
		,
	journal={{Development}}
		
			145
			145
			,
	year={2018}
		
	

}

@incollection{b55,
	
	
		,
	title={{Mechanical stretch-induced serotonin release from pulmonary neuroendocrine cells: implications for lung development}}
		,
	author={{
			JPan
		} and {
			ICopland
		} and {
			MPost
		} and {
			HYeger
		} and {
			ECutz
		}}
		
		
		
		
		10.1152/ajplung.00167
	
	
		,
	journal={{Am J Physiol Lung Cell Mol Physiol}}
		
			290
			1
			
			,
	year={2006 Jan}
		
	

}

@incollection{b56,
	
	
		,
	title={{Distal angiogenesis: a new concept for lung vascular morphogenesis}}
		,
	author={{
			MCParera
		} and {
			MVan Dooren
		} and {
			MVan Kempen
		} and {
			RDe Krijger
		} and {
			FGrosveld
		} and {
			DTibboel
		}}
		
		
		
		
		
		doi: 10.1152/ ajplung.00148
	
	
		,
	journal={{Am. J. Physiol. Lung Cell. Mol. Physiol}}
		
			288
			
			,
	year={2005. 2004}
		
	

}

@incollection{b57,
	
	
		,
	title={{The vascular endothelial growth factor (VEGF) isoforms, differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF}}
		,
	author={{
			JEPark
		} and {
			GAKeller
		} and {
			NFerrara
		}}
		
		
		10.1091/mbc.4.12.1317
	
	
		,
	journal={{Mol. Biol. Cell}}
		
			4
			
			,
	year={1993}
		
	

}

@incollection{b58,
	
	
		,
	title={{FGF-10 is a chemotactic factor for distal epithelial buds during lung development}}
		,
	author={{
			WYPark
		} and {
			BMiranda
		} and {
			DLebeche
		} and {
			GHashimoto
		} and {
			WVCardoso
		}}
		
		
		
		
		10.1006/dbio.1998.8994
	
	
		,
	journal={{Dev. Biol}}
		
			201
			
			,
	year={1998}
		
	

}

@incollection{b59,
	
	
		,
	title={{Lung development and repair: contribution of the ciliated lineage}}
		,
	author={{
			ELRawlins
		} and {
			LEOstrowski
		} and {
			SHRandell
		} and {
			BL MHogan
		}}
		
		
		
		10.1073/pnas.0610770104
	
	
		,
	booktitle={{Proc. Natl. Acad. Sci. USA2007}}
				Natl. Acad. Sci. USA2007
		
			104
			
		
	

}

@incollection{b60,
	
	
		,
	title={{The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells}}
		,
	author={{
			ELRawlins
		} and {
			CPClark
		} and {
			YXue
		} and {
			BLHogan
		}}
		
		
		
		10.1242/ dev.037317
	
	
		,
	journal={{Development}}
		
			136
			
			,
	year={2009a}
		
	

}

@incollection{b61,
	
	
		,
	title={{The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium}}
		,
	author={{
			ELRawlins
		} and {
			TOkubo
		} and {
			YXue
		} and {
			DMBrass
		} and {
			RLAuten
		} and {
			HHasegawa
		} and {
			FWang
		} and {
			BLHogan
		}}
		
		
		
		
		
		
		
		10.1016/j.stem.2009.04.002
	
	
		,
	journal={{Cell Stem Cell}}
		
			4
			
			,
	year={2009b}
		
	

}

@incollection{b62,
	
	
		,
	title={{Evidence for the presence of lipofibroblasts in human lung}}
		,
	author={{
			VKRehan
		} and {
			SSugano
		} and {
			YWang
		} and {
			JSantos
		} and {
			SRomero
		} and {
			CDasgupta
		} and {
			MPKeane
		} and {
			MTStahlman
		} and {
			JTorday
		}}
		
		
		
		
		
		
		
		
		379-393.10.1080/01902140600880257
	
	
		,
	journal={{Exp. Lung Res}}
		
			32
			,
	year={2006}
		
	

}

@incollection{b63,
	
	
		,
	title={{Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration}}
		,
	author={{
			SDReynolds
		} and {
			AGiangreco
		} and {
			JHPower
		} and {
			BRStripp
		}}
		
		
		
	
	
		,
	journal={{Am. J}}
		
	

}

@incollection{b64,
	
	
		,
	title={{}}
		10.1016/S0002-9440
	
	
		,
	journal={{Pathol}}
		
			156
			
			,
	year={2000}
		
	

}

@book{b65,
	
	
		,
	title={{}}
		,
	author={{
			-X
		}}
		
	

}

@incollection{b66,
	
	
		,
	title={{Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways}}
		,
	author={{
			SDReynolds
		} and {
			PRReynolds
		} and {
			GSPryhuber
		} and {
			JDFinder
		} and {
			BRStripp
		}}
		
		
		
		
		1498-1509.10.1164/rccm.200204-285OC
	
	
		,
	journal={{Am. J. Respir. Crit. Care Med}}
		
			166
			,
	year={2002}
		
	

}

@incollection{b67,
	
	
		,
	title={{Basal cells as stem cells of the mouse trachea and human airway epithelium}}
		,
	author={{
			JRRock
		} and {
			MWOnaitis
		} and {
			ELRawlins
		} and {
			YLu
		} and {
			CPClark
		} and {
			YXue
		} and {
			SHRandell
		} and {
			BLHogan
		}}
		
		
		
		
		
		
		
		12771-12775.10.1073/pnas.090685010
	
	
		,
	journal={{Proc. Natl. Acad. Sci. USA}}
		
			106
			,
	year={2009}
		
	

}

@incollection{b68,
	
	
		,
	title={{Vlodavsky I Basic fibroblast growth-factor is an extracellular-matrix component required for supporting the proliferation of vascular endothelial-cells and the differentiation of Pc12 cells}}
		,
	author={{
			SRogelj
		} and {
			MKlagsbrun
		} and {
			RAtzmon
		} and {
			MKurokawa
		} and {
			AHaimovitz
		} and {
			ZFuks
		}}
		
		
		
		
		
	
	
		,
	journal={{J Cell Biol}}
		
			109
			
			,
	year={1989}
		
	

}

@book{b69,
	
	
		,
	title={{Control of HIF-1{alpha} and vascular signaling in fetal lung involves cross talk between mTORC1 and the}}
		,
	author={{
			CLScott
		} and {
			DJWalker
		} and {
			ECwiklinski
		} and {
			CTait
		} and {
			ARTee
		} and {
			SCLand
		}}
		
		
		
		
		
		FGF-10/
		
	

}

@incollection{b70,
	
	
		,
	title={{FGFR2b/Spry2 airway branching periodicity clock}}
		10.1152/ajplung.00348.2009
	
	
		,
	journal={{Am. J. Physiol. Lung Cell. Mol. Physiol}}
		
			299
			
			,
	year={2010}
		
	

}

@incollection{b71,
	
	
		,
	title={{Effect of aging on respiratory system physiology and immunology}}
		,
	author={{
			GSharma
		} and {
			JGoodwin
		}}
		
		10.2147/ciia.2006.1.3.25
	
	
		,
	journal={{Clin. Interv. Aging}}
		
			1
			
			,
	year={2006}
		
	

}

@incollection{b72,
	
	
		,
	title={{Development of the lung}}
		,
	author={{
			JCSchittny
		}}
		427-444.10.1007/s00441-016-254
	
	
		,
	journal={{Cell Tissue Res}}
		
			367
			,
	year={2017}
		
	

}

@incollection{b73,
	
	
		,
	title={{Morphogenesis of the mammalian lung: aspects of structure and extracellular matrix components}}
		,
	author={{
			JCSchittny
		} and {
			PHBurri
		}}
		
	
	
		,
	booktitle={{Lung development and regeneration. Marcel Dekker}}
				,
	editor={
			DMassaro
			GDMassaro
			PChambon
		}
		New York
		
			,
	year={2004}
			
		
	

}

@incollection{b74,
	
	
		,
	title={{Development and growth of the lung}}
		,
	author={{
			JCSchittny
		} and {
			PHBurri
		} and {
			APFishman
		} and {
			JAElias
		} and {
			JAFishman
		} and {
			MAGrippi
		} and {
			LRKaiser
		}}
		
		
		
		
		
		
	
	
		,
	booktitle={{Senior RM (eds) Fishman's pulmonary diseases and disorders}}
				New-York
		
			,
	publisher={McGraw-Hill}
			,
	year={2008}
			1
			
		
	

}

@incollection{b75,
	
	
		,
	title={{Múltiplas populações estromais contribuem para a fibrose pulmonar sem evidências de transição epitelial para mesenquimal}}
		,
	author={{
			JRRock
		}}
		doi: 10.1073 / pnas.1117988108
	
	
		,
	journal={{Proc Natl Acad Sci US A}}
		
			108
			
			,
	year={2011}
		
	

}

@incollection{b76,
	
	
		,
	title={{Origins, paisagem genética e terapias emergentes de câncer de pulmão de pequenas células}}
		,
	author={{
			EASemenova
		} and {
			RNagel
		} and {
			ABerns
		}}
		
		
	
	
		,
	journal={{Genes Dev}}
		
			29
			
			,
	year={2015}
		
	

}

@book{b77,
	
	
		,
	title={{A. et alStochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors}}
		,
	author={{
			VHTeixeira
		} and {
			PNadarajan
		} and {
			TAGraham
		} and {
			CPPipinikas
		} and {
			JMBrown
		} and {
			MFalzon
		} and {
			ENye
		} and {
			RPoulsom
		} and {
			DLawrence
		} and {
			NWright
		}}
		
		
		
		
		
		
		
		
		
		10.7554/eLife.00966
		
			,
	year={2013}
			2
			e00966
		
	

}

@incollection{b78,
	
	
		,
	title={{Expression of taste receptors in solitary chemosensory cells of rodent airways}}
		,
	author={{
			MTizzano
		} and {
			MCristofoletti
		} and {
			ASbarbati
		} and {
			TEFinger
		}}
		
		
		
		10.1186/1471-2466-11-3
	
	
		,
	journal={{BMC Pulm. Med}}
		
			11
			3
			,
	year={2011}
		
	

}

@incollection{b79,
	
	
		,
	title={{Clonal dynamics reveal two distinct populations of basal cells in slow-turnover airway epithelium}}
		,
	author={{
			JKWatson
		} and {
			SRulands
		} and {
			ACWilkinson
		} and {
			AWuidart
		} and {
			MOusset
		} and {
			AVan Keymeulen
		} and {
			BGöttgens
		} and {
			CBlanpain
		} and {
			BDSimons
		} and {
			ELRawlins
		}}
		
		
		
		
		
		
		
		
		
		10.1016/j.celrep.2015.06.01
	
	
		,
	journal={{Cell Rep}}
		
			12
			
			,
	year={2015}
		
	

}

@incollection{b80,
	
	
		,
	title={{miR-375 regulates rat alveolar epithelial cell trans-differentiation by inhibiting Wnt/?-catenin pathway}}
		,
	author={{
			YWang
		} and {
			CHuang
		} and {
			NReddy Chintagari
		} and {
			MBhaskaran
		} and {
			TWeng
		} and {
			YGuo
		} and {
			XXiao
		} and {
			LLiu
		}}
		
		
		
		
		
		
		
	
	
		,
	journal={{Nucleic Acids Res}}
		
			41
			
			,
	year={2013b}
		
	

}

@incollection{b81,
	
	
		,
	title={{Development and regeneration of Sox2+ endoderm progenitors are regulated by a Hdac1/2-Bmp4/Rb1 regulatory pathway}}
		,
	author={{
			YWang
		} and {
			YTian
		} and {
			MPMorley
		} and {
			MMLu
		} and {
			FJDemayo
		} and {
			ENOlson
		} and {
			EEMorrisey
		}}
		
		
		
		
		
		
	
	
		,
	journal={{Dev. Cell}}
		
			24
			
			,
	year={2013c}
		
	

}

@incollection{b82,
	
	
		,
	title={{AMaternally imprinted microRNAs are differentially expressed during mouse and human lung development}}
		,
	author={{
			AEWilliams
		} and {
			SAMoschos
		} and {
			MMPerry
		} and {
			PJBarnes
		} and {
			MLindsay
		}}
		
		
		
		
	
	
		,
	journal={{Dev. Dyn}}
		
			236
			
			,
	year={2007}
		
	

}

@incollection{b83,
	
	
		,
	title={{The Clara cell: a "Third Reich eponym"?}}
		,
	author={{
			AWinkelmann
		} and {
			TNoack
		}}
		
	
	
		,
	journal={{Eur Respir J}}
		
			36
			
			,
	year={2010}
		
	

}

@incollection{b84,
	
	
		,
	title={{Lung structure at preterm and term birth}}
		,
	author={{
			JCWoods
		} and {
			JCSchittny
		}}
		
	
	
		,
	booktitle={{Fetal lung development -clinical correlates & future technologies}}
				,
	editor={
			AHJobe
			JAWhitsett
			SHAbman
		}
		New York
		
			,
	publisher={Cambridge University Press}
			,
	year={2016}
			
		
	

}

@incollection{b85,
	
	
		,
	title={{On the tricks alveolar epithelial cells play to make a good lung}}
		,
	author={{
			ERWeibel
		}}
	
	
		,
	journal={{Am J Respir Crit Care Med}}
		
			191
			
			,
	year={2015}
		
	

}

@incollection{b86,
	
	
		,
	title={{FGF9 and SHH regulate mesenchymal Vegfa expression and development of the pulmonary capillary network}}
		,
	author={{
			ACWhite
		} and {
			KJLavine
		} and {
			DMOrnitz
		}}
		
		
		10.1242/dev.004879
	
	
		,
	journal={{Development}}
		
			134
			
			,
	year={2007}
		
	

}

@incollection{b87,
	
	
		,
	title={{The hop works downstream of Nkx2.1 and GATA6 to mediate the HDAC-dependent negative regulation of lung gene expression}}
		,
	author={{
			ZYin
		} and {
			LGonzales
		} and {
			VKolla
		} and {
			NRath
		} and {
			YZhang
		} and {
			MMLu
		} and {
			SKimura
		} and {
			PLBallard
		} and {
			MFBeers
		} and {
			JAEpstein
		}}
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Am. J. Physiol. Pulmonary cell Mol. Physiol}}
		
			291
			
			,
	year={2006}
		
	

}

@incollection{b88,
	
	
		,
	title={{Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor}}
		,
	author={{
			WJZacharias
		} and {
			DBFrank
		} and {
			JAZepp
		} and {
			MPMorley
		} and {
			FAAlkhaleel
		} and {
			JKong
		} and {
			SZhou
		} and {
			ECantu
		} and {
			EEMorrisey
		}}
		
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Nature}}
		
			555
			
			,
	year={2018}
		
	

}