The incessant upsurge of antibiotic resistance and adverse side effects of many commercially accessible antibiotics has undoubtedly warranted the screening of diverse parts of plants to discover new ingredients that can serve as a substitute in prevention and cure of infections and diseases. Fresh leave samples of Ocimumgratissimum were collected, air-dried at room temperature and then blended to powder. The extraction was done using a vacuum evaporator with distilled water and absolute ethanol as the solvents. The extracts were reconstituted with dimethyl sulphoxide (DMSO) to obtain concentrations of 25 mg/ml, 50 mg/ml, 100 mg/ml and 200 mg/ml. The extracts were tested against bacterial isolates obtained from the meat of periwinkle snail (Tympanotonusfuscatus). Agar well diffusion technique was used to evaluate the antibacterial susceptibility of the extracts.