@incollection{,
	
					
					
					64E8A310A2892243B0505A59E9CFAFDF
				,
	author={{Dr. UmarSaeed} and {National University of Sciences and Technology (NUST), Islamabad Pakistan.}},
	journal={{Global Journal of Medical Research}},
	journal={{GJMR}}2249-46180975-588810.34257/GJMR,
	address={Cambridge, United States},
	publisher={Global Journals Organisation}12114752
}

@book{b0,
	
	
		,
	title={{Cyclin Dependent kinase}}
		,
	author={{
			SinoBiological
		}}
		
		
	

}

@incollection{b1,
	
	
		,
	title={{CDK activation by non-cyclin proteins}}
		,
	author={{
			AngelRNebreda
		}}
	
	
		,
	journal={{Curr. Opi. in Cell Biol}}
		
			18
			2
			
			,
	year={2006}
		
	

}

@incollection{b2,
	
	
		,
	title={{RINGO C is required to sustain the spindle assembly checkpoint}}
		,
	author={{
			MSilvana
		} and {
			DCarcer
		} and {
			Guillermo
		}}
		
		
	
	
		,
	journal={{J. Cell. Sci}}
		
			123
			15
			
			,
	year={2010}
		
	

}

@book{b3,
	
	
		,
	title={{}}
		,
	author={{
			KBUniprot
		} and {
			Human
		}}
		
		
		
	

}

@incollection{b4,
	
	
		,
	title={{Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin dependent kinases cdc2, cdk2 and cdk5}}
		,
	author={{
			LMeijer
		} and {
			ABorgne
		} and {
			OMulner
		}}
		
		
	
	
		,
	journal={{Eur. J. Biochem}}
		
			243
			1-2
			
			,
	year={1997}
		
	

}

@incollection{b5,
	
	
		,
	title={{The Cell Cycle: Principles of Control}}
		,
	author={{
			DavidOMorgan
		}}
	
	
		,
	journal={{Cyclin Dependent Kinase}}
		
			,
	year={2007}
		
	
	,
	note={New. Sci. Press.. 1st ed}

}

@incollection{b6,
	
	
		,
	title={{}}
		,
	author={{
			NRBrown
		} and {
			JSinclair
		}}
		
	
	
		,
	journal={{CDK Activating Kinase. Lab. Mol. Biophy}}
		
			,
	year={2001}
		
	

}

@incollection{b7,
	
	
		,
	title={{CAK-Cyclin-dependent Activating Kinase: a key kinase in cell cycle control and a target for drugs}}
		,
	author={{
			GLolli
		} and {
			LNJohnson
		}}
		
	
	
		,
	journal={{Cell. Cyc}}
		
			4
			4
			
			,
	year={2005}
		
	

}

@book{b8,
	
	
		,
	title={{}}
		,
	author={{
			Wikipedia
		} and {
			Cdk
		} and {
			Kinase
		}}
		
		
		
		
	

}

@incollection{b9,
	
	
		,
	title={{Association of CDK activating kinase subunits with transcription factor TFIIH}}
		,
	author={{
			HSerizawa
		} and {
			TPMakela
		} and {
			JWConaway
		}}
		
		
	
	
		,
	journal={{Nat}}
		
			374
			
			,
	year={1994}
		
	

}

@incollection{b10,
	
	
		,
	title={{CDK activating kinase complex is a component of human transcription factor TFIIH}}
		,
	author={{
			RSheikhattar
		} and {
			FMermelstein
		} and {
			RPFisher
		}}
		
		
	
	
		,
	journal={{Nat}}
		
			374
			
			,
	year={1994}
		
	

}

@book{b11,
	
	
		,
	title={{Activation of CDKs by CAK: CAK in TFIIH}}
		,
	author={{
			AKeriel
		} and {
			JMEgly
		}}
		
		
			,
	year={2003}
			,
	publisher={Landes Bioscience}
			,
	address={Austin, TX, USA}
		
	
	,
	note={The CDK-Activating Kinase (CAK)}

}

@book{b12,
	
	
		,
	title={{Isolation of genes by complementation in yeast: molecular cloning of a cell-cycle gene}}
		,
	author={{
			KANasmyth
		} and {
			SIReed
		}}
		
		
	

}

@incollection{b13,
	
	
		,
	title={{Distinct roles for cyclin-dependent kinases in cell cycle control}}
		,
	author={{
			SVan Den Heuvel
		} and {
			EHarlow
		}}
		
	
	
		,
	journal={{Sci}}
		
			262
			
			,
	year={1993}
		
	

}

@incollection{b14,
	
	
		,
	title={{Mitosis in transition}}
		,
	author={{
			RWKing
		} and {
			PKJackson
		} and {
			MWKirschner
		}}
		
		
	
	
		,
	journal={{Cell}}
		
			79
			4
			
			,
	year={1994}
		
	

}

@incollection{b15,
	
	
		,
	title={{G1 phase progression: cycling on cue}}
		,
	author={{
			CJSherr
		}}
	
	
		,
	journal={{Cell}}
		
			79
			4
			
			,
	year={1994}
		
	

}

@incollection{b16,
	
	
		,
	title={{}}
		,
	author={{
			BStillman
		}}
	
	
		,
	journal={{Cell Cycle Control of DNA Replication. Sci}}
		
			274
			
			,
	year={1996}
		
	

}

@incollection{b17,
	
	
		,
	title={{Cyclin-dependent kinases: Engines, clocks, and microprocessors}}
		,
	author={{
			DOMorgan
		}}
	
	
		,
	journal={{Annu. Rev. Cell. Dev. Biol}}
		
			13
			
			,
	year={1997}
		
	

}

@book{b18,
	
	
		,
	title={{The Evolution of CDK-Activating Kinases}}
		,
	author={{
			JLiu
		} and {
			ETKipreos
		}}
		
		
			,
	year={2007. NBK6518}
			,
	publisher={Landes Bioscience}
		
	

}

@incollection{b19,
	
	
		,
	title={{Cak1 is required for Kin28 phosphorylation and activation in vivo}}
		,
	author={{
			FHEspinoza
		} and {
			AFarrell
		} and {
			JLNourse
		}}
		
		
	
	
		,
	journal={{Mol. Cell. Biol}}
		
			18
			11
			
			,
	year={1998}
		
	

}

@incollection{b20,
	
	
		,
	title={{Activating phosphorylation of the Kin28p subunit of yeast TFIIH by Cak1p}}
		,
	author={{
			JKimmelman
		} and {
			PKaldis
		} and {
			CJHengartner
		}}
		
		
	
	
		,
	journal={{Mol. Cell. Biol}}
		
			19
			7
			
			,
	year={1999}
		
	

}

@incollection{b21,
	
	
		,
	title={{Transforming growth factor beta targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity}}
		,
	author={{
			HNagahara
		} and {
			SAEzhevsky
		} and {
			AMVocero-Akbani
		}}
		
		
	
	
		,
	journal={{Proc. Natl. Acad. Sci. USA}}
		
			96
			26
			
			,
	year={1999}
		
	

}

@incollection{b22,
	
	
		,
	title={{Cdc2 activation: the interplay of cyclin binding and Thr161 phosphorylation}}
		,
	author={{
			GFDraetta
		}}
	
	
		,
	journal={{Trends. Cell. Biol}}
		
			3
			9
			
			,
	year={1993}
		
	

}

@incollection{b23,
	
	
		,
	title={{Principles of cdk regulation}}
		,
	author={{
			DOMorgan
		}}
	
	
		,
	journal={{Nat}}
		
			374
			6518
			
			,
	year={1995}
		
	

}

@incollection{b24,
	
	
		,
	title={{Cell cycle: Will the real Cdk-activating kinase please stand up}}
		,
	author={{
			GFDraetta
		}}
	
	
		,
	journal={{Curr. Biol}}
		
			7
			1
			
			,
	year={1997}
		
	

}

@incollection{b25,
	
	
		,
	title={{A cyclin-dependent kinase-activating kinase in budding yeast unrelated to vertebrate CAK}}
		,
	author={{
			FEEspinoza
		} and {
			AFarrell
		} and {
			HErdjument-Bromage
		}}
		
		
	
	
		,
	journal={{Sci}}
		
			273
			5282
			
			,
	year={1996}
		
	

}

@incollection{b26,
	
	
		,
	title={{The Cdk-activating kinase (CAK) from budding yeast}}
		,
	author={{
			PKaldis
		} and {
			ASutton
		} and {
			MJSolomon
		}}
		
		
	
	
		,
	journal={{Cell}}
		
			86
			4
			
			,
	year={1996}
		
	

}

@incollection{b27,
	
	
		,
	title={{Civ1 (CAK in vivo), a novel Cdk-activating kinase}}
		,
	author={{
			JYThuret
		} and {
			JGValay
		} and {
			GFaye
		}}
		
		
	
	
		,
	journal={{Cell}}
		
			86
			4
			
			,
	year={1996}
		
	

}

@incollection{b28,
	
	
		,
	title={{Crystal structure of human cdk2: implications for the regulation of cyclin-dependent kinases by phosphorylation and cyclin binding}}
		,
	author={{
			DeBondt
		} and {
			HLRosenblatt
		} and {
			JJancarik
		} and {
			J
		}}
		
		
		
	
	
		,
	journal={{Nat}}
		
			363
			
			,
	year={1993}
		
	

}

@incollection{b29,
	
	
		,
	title={{Mechanism of CDK activation revealed by the structure of a cyclin A-CDK2 complex}}
		,
	author={{
			PDJeffrey
		} and {
			AARusso
		} and {
			KPolyak
		}}
		
		
	
	
		,
	journal={{Nat}}
		
			376
			
			,
	year={1995}
		
	

}

@incollection{b30,
	
	
		,
	title={{A cyclin-dependent kinase-activating kinase (CAK) in budding yeast unrelated to vertebrate CAK}}
		,
	author={{
			FHEspinoza
		} and {
			AFarrell
		} and {
			HErdjument-Bromage
		}}
		
		
	
	
		,
	journal={{Sci}}
		
			273
			5282
			
			,
	year={1996}
		
	

}

@incollection{b31,
	
	
		,
	title={{Cdk7 is essential for mitosis and for in vivo Cdk-activating kinase activity}}
		,
	author={{
			SLarochelle
		} and {
			JPandur
		} and {
			RPFisher
		}}
		
		
	
	
		,
	journal={{Genes. Dev}}
		
			12
			3
			
			,
	year={1998}
		
	

}

@incollection{b32,
	
	
		,
	title={{The Cdkactivating kinase Cak1p promotes meiotic S phase through Ime2p}}
		,
	author={{
			KSchindler
		} and {
			KRBenjamin
		} and {
			AMartin
		}}
		
		
	
	
		,
	journal={{Mol. Cell. Biol}}
		
			23
			23
			
			,
	year={2003}
		
	

}

@incollection{b33,
	
	
		,
	title={{The CDKactivating kinase (Cak1p) from budding yeast has an unusual ATP-binding pocket}}
		,
	author={{
			DAEnke
		} and {
			PKaldis
		} and {
			JKHolmes
		}}
		
		
	
	
		,
	journal={{J. Biol. Chem}}
		
			274
			4
			
			,
	year={1999}
		
	

}

@incollection{b34,
	
	
		,
	title={{Activation of the Bur1-Bur2 cyclindependent kinase complex by Cak1}}
		,
	author={{
			SYao
		} and {
			GPrelich
		}}
		
	
	
		,
	journal={{Mol. Cell. Biol}}
		
			22
			19
			
			,
	year={2002}
		
	

}

@incollection{b35,
	
	
		,
	title={{Phosphorylation by Cak1 regulates the C-terminal domain kinase Ctk1 in Saccharomyces cerevisiae}}
		,
	author={{
			DOstapenko
		} and {
			MSolomon
		}}
		
	
	
		,
	journal={{J. Mol. Cell. Biol}}
		
			25
			10
			
			,
	year={2005}
		
	

}

@incollection{b36,
	
	
		,
	title={{Cak1 is required for Kin28 phosphorylation and activation in vivo}}
		,
	author={{
			FHEspinoza
		} and {
			AFarrell
		} and {
			JLNourse
		}}
		
		
	
	
		,
	journal={{Mol Cell Biol}}
		
			18
			11
			
			,
	year={1998}
		
	

}

@incollection{b37,
	
	
		,
	title={{Localization and regulation of the cdk-activating kinase (Cak1p) from budding yeast}}
		,
	author={{
			PKaldis
		} and {
			ZWPitluk
		} and {
			IABany
		}}
		
		
	
	
		,
	journal={{J. Cell. Sci}}
		
			111
			24
			
			,
	year={1998}
		
	

}

@incollection{b38,
	
	
		,
	title={{In-Silico Binding of ATP to Protein Kinase C Delta: Insights into the Structure and Active Site}}
		,
	author={{
			USaeed
		} and {
			YWaheed
		} and {
			AAnwar
		}}
		
		
	
	
		,
	journal={{EJSR}}
		
			52
			2
			
			,
	year={2011}
		
	

}

@incollection{b39,
	
	
		,
	title={{In silico identification of BIM-1 (2-methyl-1H-indol-3-yl) as a potential therapeutic agent against elevated protein kinase C beta associated diseases}}
		,
	author={{
			USaeed
		} and {
			NNawaz
		} and {
			YWaheed
		}}
		
		
	
	
		,
	journal={{African. J. Biotech}}
		
			11
			19
			
			,
	year={2012}
		
	

}