\documentclass[11pt,twoside]{article}\makeatletter

\IfFileExists{xcolor.sty}%
  {\RequirePackage{xcolor}}%
  {\RequirePackage{color}}
\usepackage{colortbl}
\usepackage{wrapfig}
\usepackage{ifxetex}
\ifxetex
  \usepackage{fontspec}
  \usepackage{xunicode}
  \catcode`⃥=\active \def⃥{\textbackslash}
  \catcode`❴=\active \def❴{\{}
  \catcode`❵=\active \def❵{\}}
  \def\textJapanese{\fontspec{Noto Sans CJK JP}}
  \def\textChinese{\fontspec{Noto Sans CJK SC}}
  \def\textKorean{\fontspec{Noto Sans CJK KR}}
  \setmonofont{DejaVu Sans Mono}
  
\else
  \IfFileExists{utf8x.def}%
   {\usepackage[utf8x]{inputenc}
      \PrerenderUnicode{–}
    }%
   {\usepackage[utf8]{inputenc}}
  \usepackage[english]{babel}
  \usepackage[T1]{fontenc}
  \usepackage{float}
  \usepackage[]{ucs}
  \uc@dclc{8421}{default}{\textbackslash }
  \uc@dclc{10100}{default}{\{}
  \uc@dclc{10101}{default}{\}}
  \uc@dclc{8491}{default}{\AA{}}
  \uc@dclc{8239}{default}{\,}
  \uc@dclc{20154}{default}{ }
  \uc@dclc{10148}{default}{>}
  \def\textschwa{\rotatebox{-90}{e}}
  \def\textJapanese{}
  \def\textChinese{}
  \IfFileExists{tipa.sty}{\usepackage{tipa}}{}
\fi
\def\exampleFont{\ttfamily\small}
\DeclareTextSymbol{\textpi}{OML}{25}
\usepackage{relsize}
\RequirePackage{array}
\def\@testpach{\@chclass
 \ifnum \@lastchclass=6 \@ne \@chnum \@ne \else
  \ifnum \@lastchclass=7 5 \else
   \ifnum \@lastchclass=8 \tw@ \else
    \ifnum \@lastchclass=9 \thr@@
   \else \z@
   \ifnum \@lastchclass = 10 \else
   \edef\@nextchar{\expandafter\string\@nextchar}%
   \@chnum
   \if \@nextchar c\z@ \else
    \if \@nextchar l\@ne \else
     \if \@nextchar r\tw@ \else
   \z@ \@chclass
   \if\@nextchar |\@ne \else
    \if \@nextchar !6 \else
     \if \@nextchar @7 \else
      \if \@nextchar (8 \else
       \if \@nextchar )9 \else
  10
  \@chnum
  \if \@nextchar m\thr@@\else
   \if \@nextchar p4 \else
    \if \@nextchar b5 \else
   \z@ \@chclass \z@ \@preamerr \z@ \fi \fi \fi \fi
   \fi \fi  \fi  \fi  \fi  \fi  \fi \fi \fi \fi \fi \fi}
\gdef\arraybackslash{\let\\=\@arraycr}
\def\@textsubscript#1{{\m@th\ensuremath{_{\mbox{\fontsize\sf@size\z@#1}}}}}
\def\Panel#1#2#3#4{\multicolumn{#3}{){\columncolor{#2}}#4}{#1}}
\def\abbr{}
\def\corr{}
\def\expan{}
\def\gap{}
\def\orig{}
\def\reg{}
\def\ref{}
\def\sic{}
\def\persName{}\def\name{}
\def\placeName{}
\def\orgName{}
\def\textcal#1{{\fontspec{Lucida Calligraphy}#1}}
\def\textgothic#1{{\fontspec{Lucida Blackletter}#1}}
\def\textlarge#1{{\large #1}}
\def\textoverbar#1{\ensuremath{\overline{#1}}}
\def\textquoted#1{‘#1’}
\def\textsmall#1{{\small #1}}
\def\textsubscript#1{\@textsubscript{\selectfont#1}}
\def\textxi{\ensuremath{\xi}}
\def\titlem{\itshape}
\newenvironment{biblfree}{}{\ifvmode\par\fi }
\newenvironment{bibl}{}{}
\newenvironment{byline}{\vskip6pt\itshape\fontsize{16pt}{18pt}\selectfont}{\par }
\newenvironment{citbibl}{}{\ifvmode\par\fi }
\newenvironment{docAuthor}{\ifvmode\vskip4pt\fontsize{16pt}{18pt}\selectfont\fi\itshape}{\ifvmode\par\fi }
\newenvironment{docDate}{}{\ifvmode\par\fi }
\newenvironment{docImprint}{\vskip 6pt}{\ifvmode\par\fi }
\newenvironment{docTitle}{\vskip6pt\bfseries\fontsize{22pt}{25pt}\selectfont}{\par }
\newenvironment{msHead}{\vskip 6pt}{\par}
\newenvironment{msItem}{\vskip 6pt}{\par}
\newenvironment{rubric}{}{}
\newenvironment{titlePart}{}{\par }

\newcolumntype{L}[1]{){\raggedright\arraybackslash}p{#1}}
\newcolumntype{C}[1]{){\centering\arraybackslash}p{#1}}
\newcolumntype{R}[1]{){\raggedleft\arraybackslash}p{#1}}
\newcolumntype{P}[1]{){\arraybackslash}p{#1}}
\newcolumntype{B}[1]{){\arraybackslash}b{#1}}
\newcolumntype{M}[1]{){\arraybackslash}m{#1}}
\definecolor{label}{gray}{0.75}
\def\unusedattribute#1{\sout{\textcolor{label}{#1}}}
\DeclareRobustCommand*{\xref}{\hyper@normalise\xref@}
\def\xref@#1#2{\hyper@linkurl{#2}{#1}}
\begingroup
\catcode`\_=\active
\gdef_#1{\ensuremath{\sb{\mathrm{#1}}}}
\endgroup
\mathcode`\_=\string"8000
\catcode`\_=12\relax

\usepackage[a4paper,twoside,lmargin=1in,rmargin=1in,tmargin=1in,bmargin=1in,marginparwidth=0.75in]{geometry}
\usepackage{framed}

\definecolor{shadecolor}{gray}{0.95}
\usepackage{longtable}
\usepackage[normalem]{ulem}
\usepackage{fancyvrb}
\usepackage{fancyhdr}
\usepackage{graphicx}
\usepackage{marginnote}

\renewcommand{\@cite}[1]{#1}


\renewcommand*{\marginfont}{\itshape\footnotesize}

\def\Gin@extensions{.pdf,.png,.jpg,.mps,.tif}

  \pagestyle{fancy}

\usepackage[pdftitle={Simple UV Spectrophotometric Assay of Atorvastatin API Formulation and their Comparative Study},
 pdfauthor={}]{hyperref}
\hyperbaseurl{}

	 \paperwidth210mm
	 \paperheight297mm
              
\def\@pnumwidth{1.55em}
\def\@tocrmarg {2.55em}
\def\@dotsep{4.5}
\setcounter{tocdepth}{3}
\clubpenalty=8000
\emergencystretch 3em
\hbadness=4000
\hyphenpenalty=400
\pretolerance=750
\tolerance=2000
\vbadness=4000
\widowpenalty=10000

\renewcommand\section{\@startsection {section}{1}{\z@}%
     {-1.75ex \@plus -0.5ex \@minus -.2ex}%
     {0.5ex \@plus .2ex}%
     {\reset@font\Large\bfseries}}
\renewcommand\subsection{\@startsection{subsection}{2}{\z@}%
     {-1.75ex\@plus -0.5ex \@minus- .2ex}%
     {0.5ex \@plus .2ex}%
     {\reset@font\Large}}
\renewcommand\subsubsection{\@startsection{subsubsection}{3}{\z@}%
     {-1.5ex\@plus -0.35ex \@minus -.2ex}%
     {0.5ex \@plus .2ex}%
     {\reset@font\large}}
\renewcommand\paragraph{\@startsection{paragraph}{4}{\z@}%
     {-1ex \@plus-0.35ex \@minus -0.2ex}%
     {0.5ex \@plus .2ex}%
     {\reset@font\normalsize}}
\renewcommand\subparagraph{\@startsection{subparagraph}{5}{\parindent}%
     {1.5ex \@plus1ex \@minus .2ex}%
     {-1em}%
     {\reset@font\normalsize\bfseries}}


\def\l@section#1#2{\addpenalty{\@secpenalty} \addvspace{1.0em plus 1pt}
 \@tempdima 1.5em \begingroup
 \parindent \z@ \rightskip \@pnumwidth 
 \parfillskip -\@pnumwidth 
 \bfseries \leavevmode #1\hfil \hbox to\@pnumwidth{\hss #2}\par
 \endgroup}
\def\l@subsection{\@dottedtocline{2}{1.5em}{2.3em}}
\def\l@subsubsection{\@dottedtocline{3}{3.8em}{3.2em}}
\def\l@paragraph{\@dottedtocline{4}{7.0em}{4.1em}}
\def\l@subparagraph{\@dottedtocline{5}{10em}{5em}}
\@ifundefined{c@section}{\newcounter{section}}{}
\@ifundefined{c@chapter}{\newcounter{chapter}}{}
\newif\if@mainmatter 
\@mainmattertrue
\def\chaptername{Chapter}
\def\frontmatter{%
  \pagenumbering{roman}
  \def\thechapter{\@roman\c@chapter}
  \def\theHchapter{\roman{chapter}}
  \def\thesection{\@roman\c@section}
  \def\theHsection{\roman{section}}
  \def\@chapapp{}%
}
\def\mainmatter{%
  \cleardoublepage
  \def\thechapter{\@arabic\c@chapter}
  \setcounter{chapter}{0}
  \setcounter{section}{0}
  \pagenumbering{arabic}
  \setcounter{secnumdepth}{6}
  \def\@chapapp{\chaptername}%
  \def\theHchapter{\arabic{chapter}}
  \def\thesection{\@arabic\c@section}
  \def\theHsection{\arabic{section}}
}
\def\backmatter{%
  \cleardoublepage
  \setcounter{chapter}{0}
  \setcounter{section}{0}
  \setcounter{secnumdepth}{2}
  \def\@chapapp{\appendixname}%
  \def\thechapter{\@Alph\c@chapter}
  \def\theHchapter{\Alph{chapter}}
  \appendix
}
\newenvironment{bibitemlist}[1]{%
   \list{\@biblabel{\@arabic\c@enumiv}}%
       {\settowidth\labelwidth{\@biblabel{#1}}%
        \leftmargin\labelwidth
        \advance\leftmargin\labelsep
        \@openbib@code
        \usecounter{enumiv}%
        \let\p@enumiv\@empty
        \renewcommand\theenumiv{\@arabic\c@enumiv}%
	}%
  \sloppy
  \clubpenalty4000
  \@clubpenalty \clubpenalty
  \widowpenalty4000%
  \sfcode`\.\@m}%
  {\def\@noitemerr
    {\@latex@warning{Empty `bibitemlist' environment}}%
    \endlist}

\def\tableofcontents{\section*{\contentsname}\@starttoc{toc}}
\parskip0pt
\parindent1em
\def\Panel#1#2#3#4{\multicolumn{#3}{){\columncolor{#2}}#4}{#1}}
\newenvironment{reflist}{%
  \begin{raggedright}\begin{list}{}
  {%
   \setlength{\topsep}{0pt}%
   \setlength{\rightmargin}{0.25in}%
   \setlength{\itemsep}{0pt}%
   \setlength{\itemindent}{0pt}%
   \setlength{\parskip}{0pt}%
   \setlength{\parsep}{2pt}%
   \def\makelabel##1{\itshape ##1}}%
  }
  {\end{list}\end{raggedright}}
\newenvironment{sansreflist}{%
  \begin{raggedright}\begin{list}{}
  {%
   \setlength{\topsep}{0pt}%
   \setlength{\rightmargin}{0.25in}%
   \setlength{\itemindent}{0pt}%
   \setlength{\parskip}{0pt}%
   \setlength{\itemsep}{0pt}%
   \setlength{\parsep}{2pt}%
   \def\makelabel##1{\upshape ##1}}%
  }
  {\end{list}\end{raggedright}}
\newenvironment{specHead}[2]%
 {\vspace{20pt}\hrule\vspace{10pt}%
  \phantomsection\label{#1}\markright{#2}%

  \pdfbookmark[2]{#2}{#1}%
  \hspace{-0.75in}{\bfseries\fontsize{16pt}{18pt}\selectfont#2}%
  }{}
      \def\TheFullDate{2014-01-15 (revised: 15 January 2014)}
\def\TheID{\makeatother }
\def\TheDate{2014-01-15}
\title{Simple UV Spectrophotometric Assay of Atorvastatin API Formulation and their Comparative Study}
\author{}\makeatletter 
\makeatletter
\newcommand*{\cleartoleftpage}{%
  \clearpage
    \if@twoside
    \ifodd\c@page
      \hbox{}\newpage
      \if@twocolumn
        \hbox{}\newpage
      \fi
    \fi
  \fi
}
\makeatother
\makeatletter
\thispagestyle{empty}
\markright{\@title}\markboth{\@title}{\@author}
\renewcommand\small{\@setfontsize\small{9pt}{11pt}\abovedisplayskip 8.5\p@ plus3\p@ minus4\p@
\belowdisplayskip \abovedisplayskip
\abovedisplayshortskip \z@ plus2\p@
\belowdisplayshortskip 4\p@ plus2\p@ minus2\p@
\def\@listi{\leftmargin\leftmargini
               \topsep 2\p@ plus1\p@ minus1\p@
               \parsep 2\p@ plus\p@ minus\p@
               \itemsep 1pt}
}
\makeatother
\fvset{frame=single,numberblanklines=false,xleftmargin=5mm,xrightmargin=5mm}
\fancyhf{} 
\setlength{\headheight}{14pt}
\fancyhead[LE]{\bfseries\leftmark} 
\fancyhead[RO]{\bfseries\rightmark} 
\fancyfoot[RO]{}
\fancyfoot[CO]{\thepage}
\fancyfoot[LO]{\TheID}
\fancyfoot[LE]{}
\fancyfoot[CE]{\thepage}
\fancyfoot[RE]{\TheID}
\hypersetup{citebordercolor=0.75 0.75 0.75,linkbordercolor=0.75 0.75 0.75,urlbordercolor=0.75 0.75 0.75,bookmarksnumbered=true}
\fancypagestyle{plain}{\fancyhead{}\renewcommand{\headrulewidth}{0pt}}

\date{}
\usepackage{authblk}

\providecommand{\keywords}[1]
{
\footnotesize
  \textbf{\textit{Index terms---}} #1
}

\usepackage{graphicx,xcolor}
\definecolor{GJBlue}{HTML}{273B81}
\definecolor{GJLightBlue}{HTML}{0A9DD9}
\definecolor{GJMediumGrey}{HTML}{6D6E70}
\definecolor{GJLightGrey}{HTML}{929497} 

\renewenvironment{abstract}{%
   \setlength{\parindent}{0pt}\raggedright
   \textcolor{GJMediumGrey}{\rule{\textwidth}{2pt}}
   \vskip16pt
   \textcolor{GJBlue}{\large\bfseries\abstractname\space}
}{%   
   \vskip8pt
   \textcolor{GJMediumGrey}{\rule{\textwidth}{2pt}}
   \vskip16pt
}

\usepackage[absolute,overlay]{textpos}

\makeatother 
      \usepackage{lineno}
      \linenumbers
      
\begin{document}

             \author[1]{Dr. Safila  Naveed}

             \author[2]{Dr. Safila  Naveed}

             \affil[1]{  Faculty of Pharmacy Jinnah University for women Karachi}

\renewcommand\Authands{ and }

\date{\small \em Received: 6 December 2013 Accepted: 5 January 2014 Published: 15 January 2014}

\maketitle


\begin{abstract}
        


A rapid, simple, accurate, and economical least time consuming rosuvastatin spectrophotometric method has been developed for the assay of atorvastatin and then compare assay of brand available in Karachi,Pakistan. The assay is based on the ultraviolet UV absorbance maxima at about 244nm wavelength of atorvastatin using methanol as solvent. A sample of drug was dissolved in methanol to produce a solution containing atorvastatin. Similarly, a sample of ground tablets of different brand were extracted with methanol and diluted with the same methanol. The absorbance of sample preparation was measured at 244 nm against the solvent blank and the assay was determined by comparing with the absorbance of available brand. The method can be applied for the routine QC quantitation of atorvastatin in tablet formulation and active.

\end{abstract}


\keywords{atorvastatin, assay, uv pectrophotometry.}

\begin{textblock*}{18cm}(1cm,1cm) % {block width} (coords) 
\textcolor{GJBlue}{\LARGE Global Journals \LaTeX\ JournalKaleidoscope\texttrademark}
\end{textblock*}

\begin{textblock*}{18cm}(1.4cm,1.5cm) % {block width} (coords) 
\textcolor{GJBlue}{\footnotesize \\ Artificial Intelligence formulated this projection for compatibility purposes from the original article published at Global Journals. However, this technology is currently in beta. \emph{Therefore, kindly ignore odd layouts, missed formulae, text, tables, or figures.}}
\end{textblock*}


\let\tabcellsep& 	 	 		 
\section[{Introduction}]{Introduction}\par
torvastatin figure \hyperref[fig_0]{1} is an HMG-CoA reductase inhibitors (3-hydroxy,3-methylglutaryl-CoA), called statins. It was a breakthrough for the prevention of hypercholesterolemia and related diseases.1-3 Cholesterol has an important role in the daily functioning of the body. But, it can also have a negative effect to the development of atherosclerosis. These plaques can block the arteries, disturb blood flow, or may rupturing and causing a clot that increases blockage. The results of these blockages are very serious and can cause angina, claudication, stroke and heart attack.4 Hyperlipidemia and hypertension are correlated to each other and have additional effect on CHD coronary heart disease and associated mortality rate, since CV cardiovascular disease is closely related to some factors such as high cholesterol levels, hypertension or diabetes. In literature there are many evidences which suggest additive beneficial effects of statin combined with losartan in the treatment of hypercholesterolemia, hypertensive patients.5\par
There are several methods reported by HPLC with the statin 6-10 but there is study found that show the comparison of available brands in market.Because the therapy is very expensive an person who has any cardiovascular disorder take medicine life time when he started.Therefor it is important that they use medicine should not be expensive and give hundred \% result.\par
Author: Faculty of Pharmacy Jinnah University for Women Karachi. e-mail: safila117@yahoo.com There for in the mind of this I have checked the \% assay of different brands available in the market .\par
The aim of this study is to investigate the assay of commercially available six brands of atorvastatin in Karachi, Pakistan. number and were labeled to conatin atorvastatin 10mg per tablet. All the six brands have 5 year shelf life.\par
The serial number as an identification of purchased brands are given in Tabel 1.20 tablets of six different brand of atorvastatin from the marketed sample were weighed and crushed uniformly with the help of a mortar and pestle. By calculating the average weighed sample powder equivalent to 10 mg of atorvastatin was transferred into a volumetric flask containing 10mL methanol solvent MeOH. The solutions were sonicated for about 5 min and than make up volume upto 100 ml with water. 
\section[{d) Procedure}]{d) Procedure}\par
After preparation of standard and tablet solutions, strength of solution 100 ppm in 100 ml absorbance of the sample preparation and standard preparation in 1cm cell at the wavelength of maximum absorbance at about 244 nm, using spectrophotometer, using the blank solution. Calculate the quantity in mg, of atorvastatin per tablet. 
\section[{III.}]{III.} 
\section[{Results and Discussions}]{Results and Discussions}\par
Pharmaceutical assay was carried out by using spectrophotometer on all brands of atorvastatin tablets during the study. Table-1 shows name brand and \% assay of different brands. Table-2 ,3 are showing the descriptive within and between groups and shows result are highly significant with p value 0.000.\par
Test of hypothesis i-e ANOVA and multiple comparison of different brands of atorvastatin are given in table  {\ref 3} shows highly significant difference of all brands with each other. The proposed method for the assay of commercially available atorvastatin tablet formulation is very simple, accurate ,least time consuming and rapid. It can be easily used for routine quality control QC for monitoring the assay in the API, inprocess samples and tablet formulation. ANOVA shows between and within group F value 309348.804 with degree of freedom df value5 and 24 and p value 0.00 which shows significant results. \begin{figure}[htbp]
\noindent\textbf{1}\includegraphics[]{image-2.png}
\caption{\label{fig_0}Figure 1 :}\end{figure}
 \begin{figure}[htbp]
\noindent\textbf{1} \par 
\begin{longtable}{P{0.19893617021276597\textwidth}P{0.09042553191489361\textwidth}P{0.15914893617021275\textwidth}P{0.12659574468085105\textwidth}P{0.1519148936170213\textwidth}P{0.12297872340425531\textwidth}}
\multicolumn{2}{l}{Brand Name Serial no}\tabcellsep Average wt of tablet mg\tabcellsep Wt for 100 ppm\tabcellsep Absorbance 244 nm\tabcellsep \% assay\\
Prostatin\tabcellsep ATR-1\tabcellsep 16.43\tabcellsep 16.43\tabcellsep 0.157\tabcellsep 104.66\\
Statin\tabcellsep ATR-2\tabcellsep 16.6\tabcellsep 16.6\tabcellsep 0.137\tabcellsep 91.33\\
Fopsec\tabcellsep ATR-3\tabcellsep 15.9\tabcellsep 15.9\tabcellsep 0.099\tabcellsep 66.00\\
Winstor\tabcellsep ATR-4\tabcellsep 15.6\tabcellsep 15.6\tabcellsep 0.118\tabcellsep 78.66\\
Survive\tabcellsep ATR-5\tabcellsep 18.8\tabcellsep 18.8\tabcellsep 0.059\tabcellsep 39.33\end{longtable} \par
 
\caption{\label{tab_0}Table 1 :}\end{figure}
 \begin{figure}[htbp]
\noindent\textbf{2} \par 
\begin{longtable}{P{0.2176\textwidth}P{0.24479999999999996\textwidth}P{0.102\textwidth}P{0.15639999999999998\textwidth}P{0.07479999999999999\textwidth}P{0.0544\textwidth}}
\tabcellsep Sum of Squares\tabcellsep df\tabcellsep Mean Square\tabcellsep F\tabcellsep Sig.\\
Between Groups\tabcellsep 13328.351\tabcellsep 5\tabcellsep 2665.670\tabcellsep 309348.804\tabcellsep .000\\
Within Groups\tabcellsep .207\tabcellsep 24\tabcellsep .009\tabcellsep \tabcellsep \\
Total\tabcellsep 13328.557\tabcellsep 29\tabcellsep \tabcellsep \tabcellsep \\
\tabcellsep \tabcellsep Figure 1\tabcellsep \tabcellsep \tabcellsep \end{longtable} \par
 
\caption{\label{tab_1}Table 2 :}\end{figure}
 \begin{figure}[htbp]
\noindent\textbf{5} \par 
\begin{longtable}{P{0.015685413005272406\textwidth}P{0.08739015817223197\textwidth}P{0.22855887521968365\textwidth}P{0.0037346221441124784\textwidth}P{0.0037346221441124784\textwidth}P{0.12174868189806677\textwidth}P{0.0037346221441124784\textwidth}P{0.08440246045694201\textwidth}P{0.14415641476274166\textwidth}P{0.14415641476274166\textwidth}P{0.012697715289982425\textwidth}}
\tabcellsep \tabcellsep \multicolumn{5}{l}{\%Availability of}\tabcellsep \\
\tabcellsep \tabcellsep \multicolumn{5}{l}{different brands}\tabcellsep \\
\tabcellsep 150\tabcellsep \tabcellsep \tabcellsep \tabcellsep \tabcellsep \tabcellsep \\
\tabcellsep 100\tabcellsep \tabcellsep \tabcellsep \tabcellsep \tabcellsep \tabcellsep \\
\tabcellsep 50\tabcellsep \tabcellsep \tabcellsep \tabcellsep \tabcellsep \tabcellsep \\
\tabcellsep 0\tabcellsep \tabcellsep \tabcellsep \tabcellsep \tabcellsep \tabcellsep \\
\tabcellsep \tabcellsep ATR-\tabcellsep ATR-\tabcellsep ATR-\tabcellsep ATR-\tabcellsep ATR-\tabcellsep ATR-\\
\tabcellsep \tabcellsep 1\tabcellsep 2\tabcellsep 3\tabcellsep 4\tabcellsep 5\tabcellsep 6\\
\tabcellsep ATR2\tabcellsep \multicolumn{2}{l}{13.30467 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep 13.1835\tabcellsep 13.4258\\
\tabcellsep ATR3\tabcellsep \multicolumn{2}{l}{38.56733 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep 38.4462\tabcellsep 38.6885\\
ATR1\tabcellsep ATR4\tabcellsep \multicolumn{2}{l}{25.96600 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep 25.8448\tabcellsep 26.0872\\
\tabcellsep ATR5\tabcellsep \multicolumn{2}{l}{65.29267 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep 65.1715\tabcellsep 65.4138\\
\tabcellsep ATR6\tabcellsep \multicolumn{2}{l}{42.53133 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep 42.4102\tabcellsep 42.6525\\
\tabcellsep ATR1\tabcellsep \multicolumn{2}{l}{-13.30467 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep -13.4258\tabcellsep -13.1835\\
\tabcellsep ATR3\tabcellsep \multicolumn{2}{l}{25.26267 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep 25.1415\tabcellsep 25.3838\\
ATR2\tabcellsep ATR4\tabcellsep \multicolumn{2}{l}{12.66133 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep 12.5402\tabcellsep 12.7825\\
\tabcellsep ATR5\tabcellsep \multicolumn{2}{l}{51.98800 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep 51.8668\tabcellsep 52.1092\\
\tabcellsep ATR6\tabcellsep \multicolumn{2}{l}{29.22667 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep 29.1055\tabcellsep 29.3478\\
ATR3 ATR4\tabcellsep ATR1 ATR2 ATR4 ATR5 ATR6 ATR1 ATR2 ATR3\tabcellsep \multicolumn{2}{l}{-38.56733 * -25.26267 * -12.60133 * 26.72533 * 3.96400 * -25.96600 * -12.66133 * 12.60133 *}\tabcellsep \tabcellsep .05871 .05871 .05871 .05871 .05871 .05871 .05871 .05871\tabcellsep \tabcellsep .000 .000 .000 .000 .000 .000 .000 .000\tabcellsep -38.6885 -25.3838 -12.7225 26.6042 3.8428 -26.0872 -12.7825 12.4802\tabcellsep -38.4462 -25.1415 -12.4802 26.8465 4.0852 -25.8448 -12.5402 12.7225\tabcellsep Global Journal of\\
\tabcellsep ATR5\tabcellsep \multicolumn{2}{l}{39.32667 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep 39.2055\tabcellsep 39.4478\\
\tabcellsep ATR6\tabcellsep \multicolumn{2}{l}{16.56533 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep 16.4442\tabcellsep 16.6865\\
\tabcellsep ATR1\tabcellsep \multicolumn{2}{l}{-65.29267 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep -65.4138\tabcellsep -65.1715\\
\tabcellsep ATR2\tabcellsep \multicolumn{2}{l}{-51.98800 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep -52.1092\tabcellsep -51.8668\\
ATR5\tabcellsep ATR3 ATR4\tabcellsep \multicolumn{2}{l}{-26.72533 * -39.32667 *}\tabcellsep \tabcellsep .05871 .05871\tabcellsep \tabcellsep .000 .000\tabcellsep -26.8465 -39.4478\tabcellsep -26.6042 -39.2055\\
\tabcellsep ATR6\tabcellsep \multicolumn{2}{l}{-22.76133 *}\tabcellsep \tabcellsep .05871\tabcellsep \tabcellsep .000\tabcellsep -22.8825\tabcellsep -22.6402\end{longtable} \par
 
\caption{\label{tab_2}Table 5 :}\end{figure}
 			\footnote{© 2014 Global Journals Inc. (US)} 		 		\backmatter  			  				\begin{bibitemlist}{1}
\bibitem[Tobert ()]{b0}\label{b0} 	 		\textit{},  		 			J A Tobert 		.  	 	 		\textit{Nat. Rev. Drug Discov}  		2003. 2 p. .  	 
\bibitem[Jones et al. ()]{b1}\label{b1} 	 		\textit{},  		 			P H Jones 		,  		 			M H Davidson 		,  		 			E A Stein 		,  		 			H E Bays 		,  		 			J M Mckenney 		,  		 			E Miller 		.  	 	 		\textit{Am. J. Cardiol}  		2003. 92 p. .  	 
\bibitem[Caslake et al. ()]{b2}\label{b2} 	 		\textit{},  		 			M J Caslake 		,  		 			G Stewart 		,  		 			S P Day 		,  		 			E Daly 		.  	 	 		\textit{Atherosclerosis}  		2003. 171 p. .  	 
\bibitem[Koh et al. ()]{b4}\label{b4} 	 		\textit{},  		 			K K Koh 		,  		 			M J Quon 		,  		 			S H Han 		.  	 	 		\textit{J. Am. Heart Assoc}  		2004. 110 p. .  	 
\bibitem[Mckenney ()]{b3}\label{b3} 	 		\textit{},  		 			J M Mckenney 		.  	 	 		\textit{Am. J. Health-Syst. Pharm}  		2005. 62 p. .  	 
\bibitem[Sultana et al. ()]{b8}\label{b8} 	 		‘Determination of Enalapril and Statins In Pharmaceutical Formulations by RP-HPLC’.  		 			N Sultana 		,  		 			Arayne Ms 		,  		 			Safila Naveed 		.  	 	 		\textit{Chilean chemical society}  		2011. 56  (3)  p. .  	 
\bibitem[Sultana et al. ()]{b5}\label{b5} 	 		‘Simultaneous Determination of Captopril and Statins in API, Pharmaceutical Formulations and in Human Serum by RP-HPLC’.  		 			N Sultana 		,  		 			M S Arayne 		,  		 			Safila Naveed 		.  	 	 		\textit{J. Chin. Chem. Soc}  		2010. 57 p. .  	 
\bibitem[Sultana et al. ()]{b6}\label{b6} 	 		‘Simultaneous determination of Prazosin, Atorvastatin, Rosuvastatin and Simvastatin in API, Dosage Formulations and Human serum by RP-HPLC’.  		 			N Sultana 		,  		 			M S Arayne 		,  		 			S N Shah 		,  		 			Safila Naveed 		.  	 	 		\textit{Journal of the Chinese Chemical Society}  		2010. 57  (6)  p. .  	 
\bibitem[Arayne et al. ()]{b9}\label{b9} 	 		‘Simultaneous LC Determination of Rosuvastatin, Lisinopril, Captopril, and Enalapril in API’.  		 			M S Arayne 		,  		 			N Sultana 		,  		 			Arman Tabassum 		.  		 \xref{http://dx.doi.org/10.1007/s00044-012-9997-}{10.1007/s00044-012-9997-}.  	 	 		\textit{Pharmaceutical Dosage Formulations, and Human Serum Medicinal Chemistry Research}  		Saeeda Nadir Ali and Safila Naveed (ed.)  		2012. 21 p. .  	 
\bibitem[Sultana et al. ()]{b7}\label{b7} 	 		‘Validated Method for the Simultaneous Determination of Lisinopril, Pravastatin, Atorvastatin and Rosuvastatin in API, Formulations and Human Serum by RP-HPLC Chinese’.  		 			N Sultana 		,  		 			Arayne Ms 		,  		 			Safila Naveed 		.  		 \xref{http://dx.doi.org/10.1002/cjoc.201190226}{10.1002/cjoc.201190226}.  	 	 		\textit{Journal of Chemistry}  		2011. 29 p. .  	 
\end{bibitemlist}
 			 		 	 
\end{document}
