@incollection{,
	
					
					
					E08FC9FD8CFA08A02D87224E6B1B365F
				,
	author={{A.A.Yas} and {Ali Al -Jipouri} and {Tikrit University}},
	journal={{Global Journal of Medical Research}},
	journal={{GJMR}}2249-46180975-588810.34257/GJMR,
	address={Cambridge, United States},
	publisher={Global Journals Organisation}14515
}

@incollection{b0,
	
	
		,
	title={{The Pharmacological Treatment of Pulmonary Arterial Hypertension}}
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	author={{
			LRFrumkin
		}}
	
	
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	journal={{Pharmacological Reviews}}
		
			64
			3
			
			,
	year={2012}
		
	

}

@incollection{b1,
	
	
		,
	title={{Pharmacokinetic Evaluation of Sildenafil as a Pulmonary Hypertension Treatment}}
		,
	author={{
			M -CChaumais
		} and {
			SPerrin
		} and {
			OSitbon
		} and {
			GSimonneau
		} and {
			MHumbert
		} and {
			DMontani
		}}
		
		
		
		
		
	
	
		,
	journal={{Expert Opinion in Drug Metabolism and Toxicology}}
		
			9
			9
			
			,
	year={2013}
		
	

}

@incollection{b2,
	
	
		,
	title={{Pulmonary Drug Delivery. Part I: Physiological Factors Affecting Therapeutic Effectiveness of Aerosolized Medications}}
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	author={{
			NRLabiris
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			MBDolovich
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			56
			6
			
			,
	year={2003}
		
	

}

@incollection{b3,
	
	
		,
	title={{Nebulization Performance of Biodegradable Sildenafil -Loaded Nanoparticles using the Aeroneb ® Pro: Formulation Aspects and Nanoparticle Stability to Nebulization}}
		,
	author={{
			MBeck -Broichsitter
		} and {
			PKleimann
		} and {
			TGessler
		} and {
			WSeeger
		} and {
			TKissel
		} and {
			TSchmehl
		}}
		
		
		
		
		
	
	
		,
	journal={{International Journal of Pharmaceutics}}
		
			422
			1 -2
			
			,
	year={2012}
		
	

}

@incollection{b4,
	
	
		,
	title={{Nanoparticle -Mediated Pulmonary Drug Delivery: A Review}}
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			MParanjpe
		} and {
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		,
	journal={{International Journal of Molecular Sciences}}
		
			15
			4
			
			,
	year={2014}
		
	

}

@incollection{b5,
	
	
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	title={{In Vitro and Ex Vivo Toxicological Testing of Sildenafil -Loaded Solid Lipid Nanoparticles}}
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	author={{
			MParanjpe
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			VNeuhaus
		} and {
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		} and {
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		} and {
			SButtgenbach
		} and {
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		} and {
			CCMuller -Goymann
		}}
		
		
		
		
		
		
		
		
	
	
		,
	journal={{Inhalation Toxicology}}
		
			25
			9
			
			,
	year={2013}
		
	

}

@incollection{b6,
	
	
		,
	title={{Sildenafil Citrate Monohydrate -Cyclodextrin Nanosus pension Complexes for use in Metered -Dose Inhalers}}
		,
	author={{
			SSawatdee
		} and {
			HPhetmung
		} and {
			TSrichana
		}}
		
		
	
	
		,
	journal={{International Journal of Pharmaceutics}}
		
			455
			1 -2
			
			,
	year={2013}
		
	

}

@incollection{b7,
	
	
		,
	title={{Lipid -Based Carriers for Pulmonary Products: Preclinical Development and Case Studies in Humans}}
		,
	author={{
			DCipolla
		} and {
			BShekunov
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			JBlanchard
		} and {
			AHickey
		}}
		
		
		
	
	
		,
	journal={{Advanced Drug Delivery Reviews}}
		
			,
	year={2014}
		
	

}

@incollection{b8,
	
	
		,
	title={{Fabrication, Appraisal, and Transdermal Permeation of Sildenafil Citrate-Loaded Nanostructured Lipid Carriers versus Solid Lipid Nanoparticles}}
		,
	author={{
			YsrElnaggar
		} and {
			MAEl-Massik
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			OYAbdallah
		}}
		
		
	
	
		,
	journal={{International Journal Nanomedicine}}
		
			6
			
			,
	year={2011}
		
	

}

@incollection{b9,
	
	
		,
	title={{Preparation and Characterization of Metformin Hydrochloride -Compritol 888 ATO Solid Dispersion}}
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		} and {
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			BSKuchekar
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			ARChabukswar
		}}
		
		
		
	
	
		,
	journal={{Journal of Young Pharmacists}}
		
			3
			3
			
			,
	year={2011}
		
	

}

@incollection{b10,
	
	
		,
	title={{Microparticles for Inhalational Delivery of Antipseudomonal Antibiotics}}
		,
	author={{
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		} and {
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		} and {
			OVEvgenov
		} and {
			EBellas
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			JBenjamin
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		}}
		
		
		
		
		
	
	
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	journal={{The AAPS Journal}}
		
			10
			2
			
			,
	year={2008}
		
	

}

@incollection{b11,
	
	
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	title={{}}
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	author={{
			AFini
		} and {
			CCavallari
		} and {
			FOspitali
		} and {
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		}}
		
		
		
	
	
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	journal={{Theophylline -Loaded Compritol Microspheres Journal of Pharmaceutical Sciences}}
		
			100
			2
			
			,
	year={2011}
		
	

}

@incollection{b12,
	
	
		,
	title={{Formulation of Inhalable Lipid -Based Salbutamol Sulfate Microparticles by Spray Drying Technique}}
		,
	author={{
			ZDaman
		} and {
			KGilani
		} and {
			ARNajafabadi
		} and {
			HREftekhari
		} and {
			MABarghi
		}}
		
		
		
		
	
	
		,
	journal={{DARU Journal of Pharmaceutical Sciences}}
		
			50
			22
			,
	year={2014}
		
	

}

@incollection{b13,
	
	
		,
	title={{Preparation of Transfersomes Encapsulating Sildenafil Aimed for Transdermal Drug Delivery: Plackett -Burman Design and Characterization}}
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	author={{
			TAAhmed
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		,
	journal={{Journal of Liposome Research}}
		
			,
	year={2014}
		
	

}

@incollection{b14,
	
	
		,
	title={{Solid Lipid Budesonide Microparticles for Controlled Release Inhalation Therapy}}
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	author={{
			MMezzena
		} and {
			SScalia
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			PMYoung
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			DTraini
		}}
		
		
		
	
	
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	journal={{The AAPS Journal}}
		
			11
			4
			
			,
	year={2009}
		
	

}

@incollection{b15,
	
	
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	title={{Nondestruct tive Rheological Measurement of Aqueous Dispersions of Solid Lipid Nanoparticles: Effects of Lipid Types and Concentrations on Dispersion Consistency}}
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	author={{
			NSeetapan
		} and {
			PBejrapha
		} and {
			WSrinuanchai
		} and {
			SPuttipipatkhachorn
		} and {
			URuktanonchai
		}}
		
		
		
		
	
	
		,
	journal={{Drug Development and Industrial Pharmacy}}
		
			36
			9
			
			,
	year={2010}
		
	

}

@incollection{b16,
	
	
		,
	title={{Importance of Solid Lipid Nanoparticles (SLN) in Various Administration Routes and Future Perspectives}}
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	author={{
			MÜner
		} and {
			GYener
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	journal={{International Journal of Nanomedicine}}
		
			2
			3
			
			,
	year={2007}
		
	

}

@incollection{b17,
	
	
		,
	title={{Evaluation of Hydrophobic Materials as Matrices for Controlled -Release Drug Delivery}}
		,
	author={{
			AbdulQadir
		} and {
			MRahman
		} and {
			MSKarim
		} and {
			MZAkter
		} and {
			S
		} and {
			BinAwkat
		} and {
			TReza
		} and {
			MS
		}}
		
		
		
		
		
		
		
	
	
		,
	journal={{Pakistan Journal of Pharmaceutical Sciences}}
		
			16
			2
			
			,
	year={2003}
		
	

}

@incollection{b18,
	
	
		,
	title={{DDSolver: An Add-In Program for Modeling and Comparison of Drug Dissolution Profiles}}
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	author={{
			YZhang
		} and {
			MHuo
		} and {
			JZhou
		} and {
			AZou
		} and {
			WLi
		} and {
			CYao
		} and {
			SXie
		}}
		
		
		
		
		
		
	
	
		,
	journal={{The AAPS Journal}}
		
			12
			3
			
			,
	year={2010}
		
	

}

@incollection{b19,
	
	
		,
	title={{Kinetic Modeling on Drug Release from Controlled Drug Delivery Systems}}
		,
	author={{
			SDash
		} and {
			PNMurthy
		} and {
			LNath
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			PChowdhury
		}}
		
		
		
	
	
		,
	journal={{Acta Polonniae Pharmaceutica -Drug Research}}
		
			67
			3
			
			,
	year={2010}
		
	

}