Abstract

Interleukin-10 (IL-10) is an important anti-inflammatory cytokine increasing with exercise. It is stated in the literature that the increase of IL-10 after exercise may be related to muscle damage. Creatine kinase (CK) is a dimeric protein whose plasma levels are increasing especially in muscle pathologies. At the same time, it is known that it increases relating to the muscle damage caused by exercise. In this study planned, it shall be researched there is IL-10 and CK values before and immediately after the exercise according to Bruce protocol. Moreover, the changes in white blood cells shall also be examined. Those who are convenient for the test were elected from 30 healthy voluntary males in the same age group who do sports amateurly and who don#x2019;t do sport. The subjects were applied to exercise test on a treadmill according to Bruce protocol, and the blood samples were taken into heparinize tubes before and after the exercise. Evaluations were made in biochemistry and microbiology laboratories. While IL-10 levels did not change in sedentaries after the exercise (Pgt;0,05), it decreased in sportsmen (Plt;0,05). CK values increased in both of the groups after the (Plt;0,01). No regressional relation was found between IL-10 and CK values in both of the groups. The Bruce protocol we applied increased CK and leukocyte levels in sportsmen but decreased plasma IL -10 level significantly.