Soft Tissue Sarcoma (STS) in Gezira Sudan Presentation, Management and Outcome
Keywords:
Abstract
Objective: The aim of this study is to evaluate the management of soft tissue sarcoma (STS) in Medani teaching hospital & oncology hospital. In aspect of clinical presentation, surgical procedure, use of adjuvant therapy and the outcome of management. Methods: This is a retrospective descriptive study that has been reviewing a 55 patient with soft tissue sarcoma presented to the hospital during the period from January 2010 to August 2012. Results: the mean age is 51 years. The peak age range was 40-60 years, with the most common site affected by soft tissue sarcoma is the lower limbs (43.6%) and common size of presentation more than 15 cm in the greatest dimension (47.3%). (36.4%) of patients presented with past history of excision. MRI and U/S stand as the most common imaging requested (29.1%) and (30.6%) respectively. Excisional biopsy done for the majority of patients (58.2%) in which most of them has clear margin (56.4%) .The most common histological type is fibrosarcoma 19 (34.5%). All the patients under study received adjuvant therapy 29 of them treated by radiotherapy alone, 17 of them by chemotherapy alone, and 9 of them treated by both. There was high rate of recurrence in our studied sample 39 patient (70.9%) within the 1st year after surgery and 15 patients (27.3%) present with distal metastasis 10 of them to the lungs, 3 to the liver and 2 to the bone. Conclusion: The late presentation of the tumors as reflected by huge size at first presentation making the management a real challenge. Soft tissue sarcoma found to be common in our community and causing big problem in its treatment because of its high rate recurrence and delayed presentation.
Downloads
- Article PDF
- TEI XML Kaleidoscope (download in zip)* (Beta by AI)
- Lens* NISO JATS XML (Beta by AI)
- HTML Kaleidoscope* (Beta by AI)
- DBK XML Kaleidoscope (download in zip)* (Beta by AI)
- LaTeX pdf Kaleidoscope* (Beta by AI)
- EPUB Kaleidoscope* (Beta by AI)
- MD Kaleidoscope* (Beta by AI)
- FO Kaleidoscope* (Beta by AI)
- BIB Kaleidoscope* (Beta by AI)
- LaTeX Kaleidoscope* (Beta by AI)
How to Cite
References
Martin Malawer, Paul Sugarbaker (2001) Treatment of Sarcomas and Allied Diseases. 1.
Nijhuis SM, Otter R (1999) Epidemiological aspects of soft tissue sarcomas (STS)-consequences for the design of clinical STS trials. 35, 1705-1710.
Eriksson HL, Adami HO (1990) exposure to dioxins as risk factor for soft tissue sarcoma, population based case-control study. 82(6), 486-490. https://doi.org/10.1093/jnci/82.6.486
Karlsson HE, Samurlsson A, Johansson KA, Wallgren A (1998) soft tissue sarcoma after treatment of breast cancer. Swedish population based study. 34, 2068-275.
Jenson McClain KL LC, Chawick Joshi VV, PollockRT (1995) Association of Epstein-Barr virus with leiomyosarcoma in children with AIDS. 1995, 12-18.
Russell Schreiber H BF, Ponsky Macon WL (1979) A lethal complication of postmastectomy lymphedemaand regional immune deficiency. 114, 82-5.
Fung Hisada M GJ, Jr Fraumeni JF, Li FP (1998) Multiple primary cancers in families with Li-Fraumeni syndrome. 90, 606-11.
Bauer TC, Alvegﻩrd TA, Berlin O, Erlanson M, Gustafson P (2001) Monitoring referral and treatment in soft tissue sarcoma: Study based on 1,851 patients from the Scandinavian Sarcoma Group Register. 72, 150-159.
Gustafson DK, Rydholm A (1994) Soft tissue sarcoma should be treated at a tumor center: A comparison of quality of surgery in 375 patients. 65(1), 47-50. https://doi.org/10.3109/17453679408993717
R. (1998) Improving the management of soft tissue sarcoma. Diagnosis and treatment should be given in specialist centres. 317, 93-4.
R. Moser, PW (2001) Radiologic evaluation of soft tissue tumors.
Hermann G AeI, T. Miller (1992) Tumour and tumour like conditions of the soft tissue, magnetic resonance imaging features differentiating benign from malignant masses Br J Radiol. 65, 14-20.
Arkun MA, Akalin T (1997) Liposarcoma of soft tissue: MRI findings with pathologic correlation. 26, 167-72.
Ma FF, McCarthy EF (1997) Benign and malignant musculoskeletal masses: MR imaging differentiation with rim-to-center differential enhancement ratios Radiology. 202, 739-744.
Bancroft PJ, Kransdorf MJ (2002) Soft tissue tumors of the lower extremities. 40, 991-1011.
Szklaruk TE, Choi H (2003) MR imaging of common and uncommon large pelvic masses Radiographics. 23, 403-424.
J. HL (1958) Introduction: Problems of classification and diagnosis. 1958, 9-17.
A. Chang, SV (1995) Clinical evaluation and treatment of soft tissue tumors. 1995, 17-38.
Ayala RJ, Fanning CV, Flores JP, Yasco AW (1995) Core needle biopsy and fine needle aspiration in the diagnosis of bone and soft-tissue lesions. 9, 633-51.
Berardo PC, Wakely PE, Almeida MO, Frable WJ (1997) Fine-needle aspiration cytopathology of malignant fibrous histiocytoma Cancer. 81, 228-237.
Bommer RI, Mody D (1997) Fine needle aspiration biopsy in the diagnosis and management of bone lesions: a study of 450 cases Cancer. 81, 148-156.
Essner SM, Eilber FR (1990) Reirradiation for extremity soft tissue sarcomas: local control and complications.
Suit SI (1994) Role of radiation in the management of adult patients with sarcoma of soft tissue. 10, 347-56.
Y. AA (2011) clinical presentation and management of STS in patients presented to Omdurman Teaching Hospital. 2011, 48-50.
A. Digun, Buhari RG (2007) soft tissue sarcoma in black African pattern, distribution and management dilemma. 2007, 88-93.
Jonathan Lewis, Joseph Espat, James Woodruff, Murray Brennan (2000) Effect of Reresection in Extremity Soft Tissue Sarcoma. 231(5), 655-63.
Published
2013-03-29
Issue
Section
License
Copyright (c) 2013 Authors and Global Journals Private Limited
This work is licensed under a Creative Commons Attribution 4.0 International License.