Effect of Oral Administration of Chloramphenicol on Hematological Profile of Male Charles Foster Rats
Keywords:
CAP, hematotoxicity, blood cells, CF rats
Abstract
For a given organism, relevant information about the internal environment can be easily accessed by its hematological profile. Chloramphenicol being a potent broad spectrum antibiotic is used readily in eyed drop formulations and is also in food industry. In the present study, varying doses (750, 1500 and 2250 mg/kg B.Wt) of Chloramphenicol (CAP) were administered orally as single daily dosage for 24 days to Male Charles Foster rats, to assess the hematological changes associated with oral exposure to the drug. The results showed a significant (p
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