Immune Associations in Hashimoto's Thyroiditis and Related Disorders

Dan Peretianu; Cătălina Poiană; Mara Carşote; Daniela Cristina Staicu; Irina Aninişi; Bogdan Oprişan; Alexandrina Clodeanu

Authors

Dan Peretianu
Cătălina Poiană
Mara Carşote
Daniela Cristina Staicu
Irina Aninişi
Bogdan Oprişan
Alexandrina Clodeanu

Keywords:

Abstract

Material and method a) Diagnostic: A. Diagnostic of thyroid immune disease: ATPO and ATG investigation was considered as necessary and were correlated with ultrasound. B. Diagnostic of immune disease. The diagnostic was based on classical guides for every disease. 2. Patients: A. "Classical" Hashimoto thyroiditis (hyper-ATPO-emia, HT) = 1276, B. thyroiditis with isolated hyper-ATG-emia, with normal ATPO (T-ATG) = 85, C. thyroiditis "sero-negative" (normal ATPO and ATG, pathology diagnosis) = 9, D. idiopathic myxedema (hypothyroidism, no A,B,C) = 76; E. control = 1216 (no antibodies, when hypothyroidism, iatrogenic). b) Statistical analysis: χ2 test for comparing patients data with control data and z-test for comparing proportions. Results a) Immune association - in total: in HT = 237 (18.57%, p

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Immune Associations in Hashimoto’s Thyroiditis and Related Disorders. (2013). Global Journal of Medical Research, 13(8), 39-52. https://medicalresearchjournal.org/index.php/GJMR/article/view/

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Author Biography

Dan Peretianu

Dan Pereţianu is a medical professional based in Bucharest, Romania, affiliated with the Department of Endocrinology at Societatea Civilă Medicală “Povernei”. His research focuses on autoimmune thyroid disorders, particularly Hashimoto's thyroiditis, as evidenced by his work on antithyroperoxidase antibodies and immune associations. He has contributed to the understanding of echographic patterns and antibody level variations in Hashimoto's thyroiditis.

References

Boelaert K, Newby PR, Simmonds MJ, Holder RL, Carr-Smith JD, Heward JM, Manji N, Allahabadia A, Armitage M, Chatterjee KV, Lazarus JH, Pearce SH, Vaidya B, Gough SC, Franklyn JA (2010) Prevalence and relative risk of other autoimmune diseases in subjects with autoimmune thyroid disease. 123(2), 1-9.

G. Cammarota, De Marinis, A. Papa, D. Valle, L. Cuoco, R. Cianci, G. Fedeli, G. Gasbarrini (1997) Gastric Mucosa-Associated Lymphoid Tissue in Autoimmune Thyroid Diseases. 32, 869-872.

M. Centanni, M. Santaguida, Del Duca, S. Cellini, M. Gargano, L. Brusca, N. Virili, C. (2012) Concurrent presence of nonendocrine autoimmune disease with Hashimoto's thyroiditis: a systematic assessment on more than 5000 consecutive patients.

J. Clerc (2009) Scintigraphie thyroïdienne quantifiée (123I) du nodule thyroïdien : une nouvelle imagerie moléculaire. 90, 371-391.

da LM, Nisihara RM, da SR, Piovezan GC, Kotze LR Thyroid disorders in.

Daneshpazhooh M, Mostofizadeh M, Behjati J, Akhyani M, Robati RM (2006) Anti-thyroid peroxidase antibody and vitiligo: a controlled study. 6, 3.

H. Hashimoto (1912) Zur kenntnis der lymphomatösen veränderung der schilddrüse (Struma lymphomatosa). 97.

C. Irani, H. Hajj, G. Halaby (2012) Chronic urticaria and autoimmune thyroiditis. 2, 88-90.

Jennette JC, Falk RJ (1997) Small-vessel vasculitis N Engl J Med. 337(21), 1512-1523.

Niels Jerne (1985) The Generative Grammar of the Immune System. 229(4718), 1057-1059. https://doi.org/10.1126/science.4035345

Moores L, Bilello KL, Murin S (2004) Sex and gender issues and venous thromboembolism. 25, 281-297.

Kim O'connor, Douglas Paauw (2013) Herpes Zoster. 97(4), 503-522. https://doi.org/10.1016/j.mcna.2013.02.002

M. Peiser, T. Tralau, J. Heidler, A. Api, J. Arts, D. Basketter, J. English, T. Diepgen, R. Fuhlbrigge, A. Gaspari, J. Johansen, A. Karlberg, I. Kimber, J. Lepoittevin, M. Liebsch, H. Maibach, S. Martin, H. Merk, T. Platzek, T. Rustemeyer, A. Schnuch, R. Vandebriel, I. White, A. Luch (2012) Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects Current knowledge assembled at an international workshop at BfR, Germany. 69(5), 763-781. https://doi.org/10.1007/s00018-011-0846-8

Rosario Peluso, Gelsy Lupoli, Antonio Del Puente, Salvatore Iervolino, Vincenzo Bruner, Roberta Lupoli, Matteo Di Minno, Francesca Foglia, Raffaele Scarpa, Giovanni Lupoli (2011) Prevalence of thyroid autoimmunity in patients with spondyloarthropathies. 38(7), 1371-1377. https://doi.org/10.3899/jrheum.101012

D. Pereţianu, M. Saragea (1996) Definirea bolii imune - mecanisme şi criterii.[Defining the immune disease - mechanism and criteria. I, 257-365.

D. Pereţianu, G. Onose, J. Zaharescu, M. Vasilescu, L. Onose, A. Deleanu (1989) Association of rheumatoid arthritis with hypothyroidism and hypogonadism in 60 year old man Report of case and comments. 10, 313-323.

D. Pereţianu, M. Carşote, C. Poiana, D. Staicu, A. Clodeanu (2012) The concept "one thyroid specific immune mechanism - a specific thyroid disease. 1738.

D. Pereţianu, A. Tudor, M. Diculescu, C. Giucăneanu, L. Radu, L. Ionescu-Călineşti (2006) Thyroid and Cutaneous Autoimmunity - Coincidence or Common Mechanisms?. 2(1), 111-121. https://doi.org/10.4183/aeb.2006.111

Perez R, Nedzelski de Almeida J, Chen the (2009) Variations in the "Carhart Notch" and Overclosure After Laser-Assisted Stapedotomy in Otosclerosis. 30, 1033-1036.

F. Pitoia, D. Moncet, R. Glorio, Graciela Diaz, A., Rodriguez Costa, G. Carbia, S. Cabrera, H. Niepomniszcze, H. (2005) Prevalence of thyroid autoimmunity in patients with pemphigus vulgaris Medicina (B Aires). 65, 307-310.

Rebuffat SA, Nguyen B, Robert B, Castex F, Peraldi- S (2008) Antithyroperoxidase Antibody-Dependent Cytotoxicity in Autoimmune Thyroid Disease. 93, 929-934.

Pierre Ronco, Hanna Debiec (2009) Pathophysiological lessons from rare associations of immunological disorders. 24(1), 3-8. https://doi.org/10.1007/s00467-008-1009-5

K. Schallreuter, R. Lemke, O. Brandt, R. Schwartz, M. Westhofen, R. Montz, J. Berger (1994) Vitiligo and other diseases: coexistence or true association? Hamburg study on 321 patients. 188(4), 269-275. https://doi.org/10.1159/000247164

Hassan Seyrafi, Maryam Akhiani, Hamed Abbasi, Sahar Mirpour, Ali Gholamrezanezhad (2005) Evaluation of the profile of alopecia areata and the prevalence of thyroid function test abnormalities and serum autoanti-bodies in Iranian patients BMC Dermatol. 5(1), 1-5. https://doi.org/10.1186/1471-5945-5-11

M. Spina, A. Cerri, V. Piacentini, A. Stringa, U. Visca (1990) [Seronegative hashitoxicosis in patient with rheumatoid arthritis]. 15(3), 173-176.

R. Trifănescu, C. Poiană, D. Hortopan (2008) Autoimmune thyroid disease--a continuous spectrum. 46, 361-365.

O. Wu, L. Robertson, S. Twaddle, G. Lowe, P. Clark, M. Greaves, I. Walker, P. Langhorne, I. Brenkel, L. Regan, I. Greer (2006) Screening for thrombophilia in high-risk situations: systematic review and cost-effectiveness analysis. The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) study. 10(11), 1-110. https://doi.org/10.3310/hta10110

Zauli D, Deleonardi G, Foderaro S, Grassi A, Bortolotti R, Ballardini G, Bianchi FB (2001) Thyroid Autoimmunity in Chronic Urticaria. 22, 93-95.

Margit Zeher, Ildiko Horvath, Antonia Szanto, Peter Szodoray (2009) Autoimmune Thyroid Diseases in a Large Group of Hungarian Patients with Primary Sjögren's Syndrome. 19(1), 39-45. https://doi.org/10.1089/thy.2007.0398