Evaluation of Oxidative Stress and Urinary Calcium Creatinine Ratio in Pregnancy Induced Hypertension

Dr. Yadav B.

Authors

Dr. Yadav B.

Keywords:

pre-eclampsia, urinary calcium, urinary creatinine, pregnancy induced hypertension

Abstract

The present study has been undertaken to evaluate oxidative stress and urinary calcium creatinine ratio in pregnancy induced hypertension. Study was carried out in M.Y. hospital and M.G.M. medical college during 2012 to 2013. Study comprised 250 subjects 125 normal pregnant women without any complications were taken as control and 125 pregnant women with PIH were taken study cases. Normal Gynaecological examination & history based informations were taken from each subject. Fasting blood sample and morning urine samples were collected from each subject and blood samples were analyzed for free radical estimations and urine sample analyzed for calcium and creatinine. Our study shows a significant change in free radical level and siginificant fall in urine calcium creatinine ratio as compared to control study concluded that PIH can be result of increased oxidative stress. In this condition change in urinary calcium creatinine ratio indicate its relation to renal system. Study conclude that by improving oxidative stress with proper antioxidant diet or therapy we can decrease or minimize the risk associated with PIH.

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Evaluation of Oxidative Stress and Urinary Calcium Creatinine Ratio in Pregnancy Induced Hypertension. (2014). Global Journal of Medical Research, 14(5), 1-2. https://medicalresearchjournal.org/index.php/GJMR/article/view/

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References

American Gynecologist (1996) Hypertension in Pregnancy.

Levin J Should the definition of Preeclampsia include a rise in diastolic BP ≥ 15 mm of Hg. 182, 225.

North A, Taylor S (1999) Evaluation of definition of Preeclampsia. 106(8), 767. https://doi.org/10.1111/j.1471-0528.1999.tb08396.x

Chesley C (1985) Diagnosis of Preeclampsia.

Mc P, Schumacher B (1971) Serum proteins in patients with toxemic glomerular lesion. 111(4), 580. https://doi.org/10.1016/0002-9378(71)90474-1

Sibai M, Lindheimor M, Hauth J (1998) Risk factor for preeclampsia, abruptio placentae, and adverse neonatal outcome among women with chronic hypertension. 339.

Skjaerven R, Wilcox AJ, Lie RT (2002) The Interval between Pregnancies and the Risk of Preeclampsia. 346(1), 33-38. https://doi.org/10.1056/nejmoa011379

Emma Nilsson, Helena Salonen Ros, Sven Cnattingius, Paul Lichtenstein (2004) The importance of genetic and environmental effects for pre‐eclampsia and gestational hypertension: a family study. 111(3), 200-206. https://doi.org/10.1111/j.1471-0528.2004.00042x.x

Lopez- P, Casas P (2001) Braz J Med Bio. 34(10), 1227-1235.

Madazil R, Budak E, Calay Z, Aksu F (2000) Correlation between placental bed biopsy findings, vascular cell adhesion molecule and fibronectin levels in preeclampsia. 107, 14.

(1989) Clinical and biochemical aspect of pregnancy induced hypertension. 11(8), 1555-64.

R. Avendano, J. Rodiguez, B. Inzinza (1993) Hypocalcemia in preeclampsia. 58(6), 470-474.

P. Baker, G. Hackett (1994) The use of urinary albumincreatinine ratio and Ca/ Cr ratio as screening test for PIH. 83, 745-749.

Kaleli Ozcan T, Ozren M (1995) Urinary Calcium to Creatinine Ratio for Predicting Preeclampsia. 12(5), 349-387.

(1988) Calcium/creatinine ratio and microalbuminuria in the prediction of preeclampsia. 159(6), 1452-1455.

Suarez V R, J. Miyahira, D. Guinn, S. Fisher (1999) Calciuria in symptom free primigravidae women remote from term: is the response to an oral calcium challenge predictable?. 180(6P+1), 1419-1421.

Kazerooni T (2003) Calcium to creatinine ratio in a spot sample of urine for early prediction of pre-eclampsia. 80(3), 279-283.

J. Kar, Srivastava, R. Mishra (2002) Kar J, Srivastava, Mishra R K: Role of urinary calcium/ creatinine ratio in prediction of pregnancy induced hypertension: The J of Obstetrics & Gynecology of India. 52(2), 39-42.

Adjide Szmidt, Venditelli Vallerie, David Francoise, Sandra (2006) Calciuria and preeclampsia- a case control study. 125(2), 193-198.

Vahdat M, Kashanian M, Sariri E, Mehdinia M (2012) Evaluation of the value of calcium to creatinine ratio for predicting of pre-eclampsia J Matern Fetal Neonatal Med. 25(12), 2793-2794. https://doi.org/10.3109/14767058.2012.712561

Maryam Mansooreh; Kashanian, Sariri, ;. Elaheh, Mehdinia (2012) Mehrnoosh Evaluation of the value of calcium to creatinine ratio for predicting of pre-eclampsia. 2012, 2793-2794.