Implant Surface Micro-Design

Dr. Ashu Sharma

Authors

Dr. Ashu Sharma

Keywords:

implants, implant topography, implant surface micro-design, implant surface treatments

Abstract

The application of implants for dental and orthopedic surgery has increased rapidly within the past few decades. In craniomaxillofacial surgery, different implant systems have been applied, for example, for dental and bone replacement or osteosynthesis plates and screws. These implants may be made of pure titanium or a titanium alloy, usually titanium- aluminum-vanadium (Ti-6Al-4V). The surface can he turned or Machined or a coating may cover the metal base. The reason for treating the implant surface is to obtain maximum bone- implant contact and bone-implant stability and to shorten the healing time for earlier loading. The crucial aspect of pure titanium implants is the development of titanium oxide on the surface. This oxide and other known coatings for implant material do not have high wear resistance. This article thus aims to review Implant Surface Micro-design its rationale, various surface's physical and chemical properties, different types of implant surface treatments, optimum roughness of oxidized implants and controversies associated with various implant topographies. The recent advances like nanotechnology are also included.

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Implant Surface Micro-Design. (2014). Global Journal of Medical Research, 14(24), 35-51. https://medicalresearchjournal.org/index.php/GJMR/article/view/

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References

(2001) Glossary of Periodontal Terms.4th ed. 27.

Jan Eirik, Ellingsen (1998) Surface configurations of dental implants. 17, 36-46.

Lise de Jonge, Sander Leeuwenburgh, Joop Wolke, John Jansen (2008) Organic-Inorganic Surface Modifications for Titanium Implant Surfaces. https://doi.org/10.1007/s11095-008-9617-0

D. Brunette (1986) Fibroblasts on micromachined substrata orient hierarchically to grooves of different dimensions Exp Cell Res. 164(1), 11-26. https://doi.org/10.1016/0014-4827(86)90450-7

P. Clark, P. Connolly, A. Curtis, J. Dow, C. Wilkinson (1987) Topographical control of cell behaviour I Simple step cues Development. 99(3), 439-448.

P. Clark, P. Connolly, A. Curtis, J. Dow, C. Wilkinson (1990) Topographical control of cell behaviour: II. multiple grooved substrata. 108(4), 635-644. https://doi.org/10.1242/dev.108.4.635

D. Hay, E. Moreno (1979) Differential adsorption and chemical affinities of proteins for apatitic surfaces. 58(Spec Issue B), 930-42.

David Puleo, Mark Thomas (2006) Puleo, Mark V Thomas Implant Surfaces Dent Clin. 50, 323-338.

G. Macheras, D. Mpaltas, A. Kostakos, K. Tsiamtsouris, S. Koutsostathis, K. Kateros (2002) Acetabular bone response to porous tantalum. 4-2002.

A. Clemow, A. Weinstein, J. Klawitter, J. Koeneman, J. Anderson (1981) J T Weinstein, A M Klawitter, J J Koeneman, J and Anderson, J Interface mechanics of porous titanium implants. 15, 73-82. https://doi.org/10.1002/jbm.820150111

Paul Predecki, J. Stephan, B. Auslaender, Vert. Mooney, K. Kirkland (1972) E Auslaender, B A Mooney, V L and Kirkland, K Kinetics of bone growth into cylindrical channels in aluminum oxide and titanium. 6(5), 375-400. https://doi.org/10.1002/jbm.820060506

Schwartz Martin JY, Schraub Hummert TW, Simpson J, Lankford Jr (1995) et al Effect of titanium surface roughness on proliferation, differentiation, and protein synthesis of human osteoblast-like cells (MG63) J Biomed Mater Res. 29(3), 389-401.

C. Giordano, E. Sandrini, V. Busini, R. Chiesa, G. Fumagalli, G. Giavaresi (2006) A New Chemical Etching Process to Improve Endosseous Implant Osseointegration: In Vitro Evaluation on Human Osteoblast-Like Cells. 29, 772-780.

Z. Schwartz, B. Brooks, L. Swain, F. Del Toro, A. Norman, B. Boyan (1990) Production of 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 by growth zone and resting zone chondrocytes is dependent on cell maturation and is regulated by hormones and growth factors. 130(5), 2495-2504. https://doi.org/10.1210/endo.130.5.1572278

Z. Schwartz, L. Bonewald, K. Caulfield, B. Brooks, B. Boyan (1993) Direct effects of transforming growth factor-beta on chondrocytes are modulated by vitamin D metabolites in a cell maturation-specific manner Endocrinology. 132(4), 1544-1552.

B. Boyan, S. Lossdörfer, L. Wang, G. Zhao, C. Lohmann, D. Cochran (2003) et al. Osteoblasts Generate An Osteogenic Microenvironment When Grown On Surfaces With Rough Microtopographies. 6, 22-27.

C. Larsson, P. Thomsen, B. Aronsson, M. Rodahl, J. Lausmaa, B. Kasemo (1996) Bone response to surface-modified titanium implants: studies on the early tissue response to machined and electropolished implants with different oxide thicknesses. 17(6), 605-616. https://doi.org/10.1016/0142-9612(96)88711-4

J. Lausmaa, L. Mattsson, U. Rolander, B. Kasemo (1986) Chemical Composition and Morphology of Titanium Surface Oxides, Mat Res Soc Symp Proc 1986. 55, 351-359. https://doi.org/10.1557/proc-55-351

Tomas Albrektsson, Ann Wennerberg (2004) Int j prosthodont 2004. 17, 536-543.

D. Buser, R. Schenk, S. Steinemann, J. Fiorellini, C. Fox, H. Stich (1991) Influence of surface characteristics on bone integration of titanium implants. A histomorphometric study in miniature pigs. 25(7), 889-902. https://doi.org/10.1002/jbm.820250708

Gotfredsen K, Wennerberg A, Johansson C, Skovgaard T, Hjorting-Hansen E (1995) Anchorage of TiO2‐blasted, HA‐coated, and machined implants: An experimental study with rabbits. 29, 1223-1231.

T. Albrektsson, A. Wennerberg (2005) The impact of oral implants-past and future. 71, 327.

S. Best, B. Sim, M. Kayser, S. Downes (1997) The dependence of osteoblastic response on variations in the chemical composition and physical properties of hydroxyapatite J Mater Sci Mater Med. 8(2), 97-103. https://doi.org/10.1023/a:1018558816871

J. Damen, J. Ten Cate, J. Ellingsen (1991) Induction of Calcium Phosphate Precipitation by Titanium Dioxide. 70(10), 1346-1349. https://doi.org/10.1177/00220345910700100601

Ellingsen JE (1991) A study on the mechanism of protein adsorption to TiO2. 12(6), 593-596.

Bernardi G, Kawasaki T (1968) Chromatography of polypeptides and proteins on hydroxyapatite columns Biochim Biophys Acta. 160(3), 301-310.

P. Gagnon (1996) Ceramic hydroxyapatite: A new dimension in chromatography of biological molecules.

C. Baud, S. Bang, J. Very (1977) Minor elements in bone mineral and their effects on its solubility J Biol Buccale. 5(3), 195-202.

Paul Anderson, James Copenhaver, Allan Tencer, John Clark (1991) Response of cortical bone to local controlled release of sodium fluoride: The effect of implant insertion site. 9(6), 890-901. https://doi.org/10.1002/jor.1100090616

A. Shteyer, R. Liberman, A. Simkin, I. Gedalia (1977) Liberman, A Simkin and I Gedalia Effect of local application of fluoride on healing of experimental bone fractures in rabbits. 22(1), 297-302. https://doi.org/10.1007/bf02010368

Hydroxyapatite-coated implants (1992) Hydroxyapatite-coated dental implants. 36, 1-273.

P. Bessa, M. Casal, R. Reis (2008) Bone morphogenetic proteins in tissue engineering: the road from the laboratory to the clinic, part I (basic concepts) J Tissue Eng Regen Med 2008. 2(1), 1-13. https://doi.org/10.1002/term.63

P. Bessa, M. Casal, R. Reis (2008) Bone morphogenetic proteins in tissue engineering: the road from laboratory to clinic, part II (BMP delivery). 2(2-3), 81-96. https://doi.org/10.1002/term.74

H. Hahn, W. Palich (1970) Preliminary evaluation of porous metal surfaced titanium for orthopedic implants. 4(4), 571-577. https://doi.org/10.1002/jbm.820040407

Roberto Gianluca Giavaresi, Enrico Milena Fini (2008) Effect of a Multiphasic Anodic Spark Deposition Coating on the Improvement of Implant Osseointegration in the Osteopenic Trabecular Bone of Sheep. 23, 659-668.

D. Puleo, Nanci (1999) Understanding and controlling the bone-implant interface. 20, 2311-2321.

Dean JW, Culbertson KC, D'Angelo AM (1995) Fibronectin and laminin enhance gingival cell attachment to dental implant surfaces in vitro Int J Oral Maxillofac Implants. 10(6), 721-728.

E. Swope, R. James (1981) A longitudinal study on hemidesmosome formation at the dental implant-tissue overflow. 9, 412-422.

Bernhardt R, van J, Bierbaum S, Beutner R, Scharnweber D, Jansen J (2006) Osteoconductive modifications of Ti-implants in a goat defect model: characterization of bone growth with SR muCT and histology. 27(4), 670.

Schliephake H, Aref A, Scharnweber D, Bierbaum S, Roessler S, Sewing A (2005) Effect of immobilized bone morphogenic protein 2 coating of titanium implants on peri‐implant bone formation. 16, 563-569.

Rammelt S, Illert T, Bierbaum S, Scharnweber D, Zwipp H, Schneiders W (2006) Coating of titanium implants with collagen, RGD peptide and chondroitin sulfate Biomaterials. 27(32), 5561-5571.

Catherine D (2007) Reyes, Timothy A Petrie, Kellie L Burns, Zvi Schwartz, and Andrés J García Biomolecular surface coating to enhance orthopaedic tissue healing and integration Biomaterials. 28(21), 3228-3235.

Schliephake H, Scharnweber D, Dard M, Röbetaler S, Sewing A, Hüttmann C (2003) Biological performance of biomimetic calcium phosphate coating of titanium implants in the dog mandible J Biomed Mater Res A. 64(2), 225-234.

D. Chappard, E. Aguado, G. Huré, F. Grizon, M. Basle (1999) The early remodeling phases around titanium implants: a histomorphometric assessment of bone quality in a 3- and 6-month study in sheep Int J Oral Maxillofac Implants. 14(2), 189-196.

de LT, Leeuwenburgh SC, Wolke JG, Jansen JA (2008) Organic-inorganic surface modific-ations for titanium implant surfaces Pharm Res. 25(10), 2357-2369.

Yamazaki Y, Oida S, Ishihara K, Nakabayashi N (1996) Ectopic induction of cartilage and bone by bovine bone morphogenetic protein using a biodegradable polymeric reservoir J Biomed Mater Res. 30(1), 1-4.

Zellin G, Linde A (1997) Importance of delivery systems for growth-stimulatory factors in combination with osteopromotive membranes An experimental study using rhBMP-2 in rat mandibular defects J Biomed Mater Res. 35(2), 181-190.

J. Teixeira, M. Urist (1998) Bone morphogenetic protein induced repair of compartmentalized segmental diaphyseal defects Arch Orthop Trauma Surg. 117(1-2), 27-34. https://doi.org/10.1007/bf00703435

A. Reddi (1995) Cartilage morphogenesis: role of bone and cartilage morphogenetic proteins, homeobox genes and extracellular matrix Matrix Biol. 14(8), 599-606.

J. Int (2007) Stadlinger B, Pilling E, Huhle M, Mai R, Bierbaum S, Scharnweber D, et al Evaluation of osseoint-egration of dental implants coated with collagen, chondroitin sulphate and BMP-4: an animal study. 37(1), 54-59.

Chen D, Zhao M, Mundy GR (2004) Bone morpho-genetic proteins Growth Factors. 22(4), 233-241.

E. Blom, J. Verheij, J. de Blieck-Hogervorst, L. Di Silvio, C. Klein (1998) Cortical bone ingrowth in growth hormone-loaded grooved implants with calcium phosphate coatings in goat femurs. 19(1-3), 263-70.

C. Stefani, M. Machado, E. Sallum, A. Sallum, S. Toledo, F. Nociti (2000) Platelet-derived growth factor/insulin-like growth factor-1 combination and bone regeneration around implants placed into extraction sockets: a histometric study in dogs. 9(2), 126-31.

G. Fuerst (2003) et al Enhanced bone to implant contact by plateletreleasedgrowth factors in mandibular cortical bone: a histomorpho-metricstudy in minipigs Int J Oral Maxillofac. 18, 685-690.

Eduardo Anitua (2006) Enhancement of Osseointegration by Generating a Dynamic Implant Surface. 32(2), 72-76. https://doi.org/10.1563/736.1

Aladino Deranieri, Amarjit Virdi, Shinji Kuroda, Susan Shott, Yang Dai, Dale Sumner (2005) Local application of rhTGF-β2 modulates dynamic gene expression in a rat implant model. 36(5), 931-940. https://doi.org/10.1016/j.bone.2005.01.019

J. Park, J. Koak, J. Jang, C. Han, S. Kim, S. Heo (2006) Osseointegration of anodized titanium implants coated with fibroblast growth factor-fibronectin (FGF-FN) fusion protein Int J Oral Maxillofac Implants. 21(6), 859-866.

S. Munisamy, T. Vaidyanathan, J. Vaidyanathan (2008) A Bone-Like Precoating Strategy for Implants: Collagen Immobilization and Its Mineralization on Pure Titanium Implant Surface. 34(2), 67-75. https://doi.org/10.1563/1548-1336(2008)34

M. Lifland, D. Kim, K. Okazaki (1993) Mechanical properties of a Ti-6A1-4V dental implant produced by electro-discharge compaction. 14, 13-19.

J. Drummond, J. Dominici, P. Sammon, K. Okazaki, R. Geissler, M. Lifland (1995) A light and scanning electron microscopic evaluation of electrodischarge-compacted porous titanium implants in rabbit tibia. 21, 295-303.

B. Story, W. Wagner, D. Gaisser, S. Cook, A. Rust- Dawicki (1998) In vivo performance of a modified CS Ti dental implant coating. 13, 749-757.

Richard LoTzara, Tiziano Testorf, Paolo Trisi, Stephan Porter, Roberto Weinstein (1999) LoTzara,Tiziano Testorf, Paolo Trisi, Stephan S, Porter, Roberto L Weinstein A Human Histologie Anaiysis of Osseotite and Machined Surfaces Using impiants with 2 Opposing Surfaces. 19, 117-129.

Aparicio C, Gil FJ, Fonseca C, Barbosa M, Planell JA Corrosion behaviour of commercially pure titanium shot blasted with different materials and sizes of shot particles for dental implant applications. 24, 263-273.

Massaro C, Rotolo F, De F, Milella E, Napoli A, Wieland M (2002) Comparative investigation of the surface properties of commercial titanium dental implants. Part I: chemical composition. 13, 535-548.

L. Le Gu (2007) ´ehennec, A. Soueidan, P.Layrolle, Y.Amouriq. Surface treatments of titanium dental Implants for rapid osseointegration. 23(7), 844-854. https://doi.org/10.1016/j.dental.2006.06.025

Perry R (2001) Klokkevold, Paul Johnson, Soheila Dadgostari, John E Davies, Angelo Early endosseous integration enhanced by dual acid etching of titanium: a torque removal study in the rabbit Clin Oral Impl Res. 12(4), 350-357. https://doi.org/10.1034/j.1600-0501.2001.012004350.x

Christine Foley, •. Hyon, Kerns, G. David, Hallmon, W. William, Francisco Rivera-Hidalgo, Nelson, J. Carl, Robert Spears (2010) Effect of phosphate treatment of Acid-etched implants on mineral apposition rates near implants in a dog model. 25, 278-286.

D. Buser, N. Broggini, M. Wieland, R. Schenk, A. Denzer, D. Cochran (2004) et al. Enhanced Bone Apposition to a Chemically Modified SLA Titanium Surface. 83(7), 529-533. https://doi.org/10.1177/154405910408300704

D. Buser, N. Broggini, M. Wieland, R. Schenk, A. Denzer, D. Cochran, B. Hoffmann (2004) Enhanced Bone Apposition to a Chemically Modified SLA Titanium Surface. 83(7), 529-533.

Michael M (2010) Bornstein, Julia-Gabriela Wittneben, Urs Brägger, Daniel Buser Early Loading at 21 Days of Non-Submerged Titanium Implants With a Chemically Modified Sandblasted and Acid-Etched Surface: 3-Year Results of a Prospective Study in the Posterior Mandible. 81, 809-818.

M. De Maeztu, I. Braceras, J. Alava, Cosme Gay-Escoda (2007) De Maeztu, Inigo Braceras Meng ,J Inaki Alava, M Angeles Sanchez-Garces, Cosme Gay- Escoda Histomorphometric Study of Ion Implantation and Diamond-like Carbon as Dental Implant Surface Treatments in Beagle Dogs. 22, 273-279.

M. Shalabi, A. Gortemaker, M. Van (2006) Implant Surface Roughness and Bone Healing: a Systematic Review. 85(6), 496-500.

J. Int (2005) Young-Taeg Sul, Carina Johansson, Ann Wennerberg, Lee-Ra Cho, Beom-Seok Chang, Tomas Albrektsson, Optimum Surface Properties of Oxidized Implants for Reinforcement of Osseointegration: Surface Chemistry, Oxide Thickness, Porosity, Roughness, and Crystal Struc-ture. 20, 349-359.

Sul YT, Johansson C, Byon E, Albrektsson T (2005) The bone response of oxidized bioactive and nonbioactive titanium implants Biomaterials. 26(33), 6720-6730.

Wael Att, Masahiro Yamada, Takahiro Ogawa (2009) Wael Att, Masahiro Yamada, Takahiro Ogawa, Effect of Titanium Surface Characteristics on the Behavior and Function of Oral Fibroblasts Int J Oral Maxillofac Implants 2009. 24, 419-431.

Anselme K, Bigerelle M, Noel B, Lost A, Hardouin P Effect of grooved titanium substratum on human osteoblastic cell growth. 60, 529-540.

Leif Persson, Tord Berglundh, Jan Lindhe, Lars Sennerby (2001) Re-osseointegration after treatment of periimplantitis at different implant surfaces An experimental study in the dog. 12(6), 595-603. https://doi.org/10.1034/j.1600-0501.2001.120607.x

Webster J, Ejiofor U Increased osteoblast adhesion on nanophase metals: Ti, Ti6Al4V, and CoCrMo. 25, 4731-4739.

Zhou J, Chang C, Zhang R, Zhang L (2007) Hydrogels Prepared from Unsubstituted Cellulose in NaOH/Urea Aqueous Solution. 7, 804-809.

Ben-Nissan B, Choi H (2006) Sol-Gel Production of Bioactive Nanocoatings for Medical Applications. Part 1: An Introduction. 1, 311-319.

Liu M, Troczynski T, Tseng J (2001) Water-based sol-gel synthesis of hydroxyapatite: process development. 22, 1721-1730.

Kim M, Kokubo T, Fujibayashi S, Nishiguchi S, Nakamura T (2000) Bioactive macroporous titanium surface layer on titanium substrate. 5(52), 553-557.

Su-Hee Lee, Hae-Won Kim, Eun-Jung Lee, Long-Hao Li, Hyoun-Ee Kim (2006) Hydroxyapatite-TiO2 Hybrid Coating on Ti Implants. 20(3), 195-208. https://doi.org/10.1177/0885328206050518

Nishimura I, Huang Y, Butz F, Ogawa T, Lin L, Jake C (2007) Discrete deposition of hydroxyl-apatite nano particles on titanium implant with predisposing substrate micro topography accelerated osseointegration. 18, 245101.

Paulo Coelho, Marcelo Suzuki (2005) Evaluation of an IBAD thin-film process as an alternative method for surface incorporation of bioceramics on dental implants: a study in dogs. 13(1), 87-92.