Evaluation of Antimicrobial Susceptibility Pattern of Pseudomonas Aeruginosa with Special Reference to MBL Production in a Tertiary Care Hospital

Uzma Afreen; M. Praveena

Authors

Uzma Afreen
M. Praveena

Keywords:

bacterial infection, carbapenem resistance, carbapenemase, mbl producers, multi drug resistance, pseudomonas aeruginosa, routinely used antibiotics, n

Abstract

Background: Pseudomonas aeruginosa is emerging as a nosocomial pathogen by producing Metallo Beta lactamases and acquiring resistance to many antimicrobial agents. Materials and methods: 132 isolates of Pseudomonas aeruginosa from various clinical samples were tested for MBL production by double disk synergy method. Antibiotic susceptibility pattern was done by comparing non-MBL producers and MBL producers. Results: Pseudomonas aeruginosa was isolated from Pus- 39.39%, from urine-37.87%, sputum-3.03%. MBL producers were 44(33.34%), non MBL producers were 88(66.6). all MBL producers were 0% sensitive to Imipenem and Meropenem. Non MBL producers were 22% sensitive to Imipenem, 23% sensitive to Meropenem and 100% sensitive to Colistin. Both MBL and non MBL producers were showing maximum sensitivity to Colistin (100%) and Piperacillin/Tazobactam (45.4%, 95.4% respectively). Conclusion: our study showed that MBL producing Pseudomonas was isolated from all clinical samples and resistant to routinely used antibiotics and also to Imipenem and Meropenem.

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Evaluation of Antimicrobial Susceptibility Pattern of Pseudomonas Aeruginosa with Special Reference to MBL Production in a Tertiary Care Hospital. (2014). Global Journal of Medical Research, 14(48), 17-22. https://medicalresearchjournal.org/index.php/GJMR/article/view/

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