Rhodiola rosea from the Selection of Traditional Applications to the Novel Phytotherapy for the Prevention and Treatment of Serious Diseases.

Authors

  • Dr. Dr. Rafie Hamidpour

  • Dr. Soheila Hamidpour

  • Dr. Mohsen Hamidpour

  • Mrs. Mina Shahlari

Keywords:

antifatigue, antidepressant, alzheimer#x2019;s disease, cancer and memory enhancement

Abstract

Abstract not found

How to Cite

Rhodiola rosea from the Selection of Traditional Applications to the Novel Phytotherapy for the Prevention and Treatment of Serious Diseases. (2015). Global Journal of Medical Research, 15(18), 1-10. https://medicalresearchjournal.org/index.php/GJMR/article/view/

Author Biographies

Dr. Dr. Rafie Hamidpour

Dr. Rafie Hamidpour is a distinguished researcher and professor in the field of biomedical sciences, with a particular focus on the chemistry, pharmacology, and medicinal properties of natural compounds. He earned his PhD in Biomedical Sciences from the University of Bradford in 2003 and holds a doctorate in Biomedical/Bioscience from the University of Central Missouri. Dr. Hamidpour has served as a Professor at Shahid Beheshti University of Medical Sciences, School of Allied Medical Sciences, in the Department of Hematology and Blood Banking from 1990 to 2024. He is the founder and lead researcher at Pars Bioscience LLC, a research center based in Leawood, Kansas, where he investigates traditional remedies and their modern phytotherapeutic applications. His notable works include comprehensive studies on the medicinal properties of camphor, sage, frankincense, and Rhodiola rosea, exploring their potential in treating a wide range of diseases from cancer to metabolic disorders. With over 45 publications and more than 1,100 citations, Dr. Hamidpour's research bridges traditional knowledge with contemporary scientific validation, contributing significantly to the field of phytotherapy and drug targeting in cancer.

Dr. Soheila Hamidpour

Dr. Soheila Hamidpour is a researcher affiliated with Pars Bioscience in Leawood, Kansas, United States. She earned her PhD in Biomedical Sciences from the University of Bradford in 2003. With a career spanning over three decades, she has served as a Professor of Hematology and Blood Banking at Shahid Beheshti University of Medical Sciences. Her research focuses on the chemistry, pharmacology, and medicinal properties of natural products, including camphor, sage, frankincense, and Rhodiola rosea, exploring their potential in treating various diseases. Dr. Hamidpour has contributed to 52 publications, accumulating over 1,000 citations, with an h-index of 10 and an i10-index of 11.

Dr. Mohsen Hamidpour

Dr. Mohsen Hamidpour is a researcher affiliated with Pars Bioscience in Leawood, Kansas, United States. He holds a PhD in Biomedical Sciences from the University of Bradford and has served as a Professor at Shahid Beheshti University of Medical Sciences. His research focuses on the chemistry, pharmacology, and medicinal properties of natural products, including camphor, sage, frankincense, and Rhodiola rosea. With over 85 publications and more than 1,200 citations, his work has contributed significantly to the understanding of traditional remedies for various diseases. Dr. Hamidpour's h-index of 14 and i10-index of 24 reflect his impact in the field. He is also an active contributor to the academic community, with his work indexed in OpenAlex and ORCID.

Mrs. Mina Shahlari

Mina Shahlari is a researcher affiliated with Pars Bioscience in Leawood, Kansas, United States. Her work focuses on the chemistry, pharmacology, and medicinal properties of traditional remedies, including camphor, sage, frankincense, and Rhodiola rosea. She has contributed to several studies exploring the potential of these natural compounds in treating various diseases such as cancer, obesity, diabetes, depression, dementia, lupus, autism, heart disease, and other serious conditions. With 13 publications and over 930 citations, her research has garnered significant attention in the field of phytotherapy. Her h-index of 8 and i10-index of 7 reflect her growing impact in the scientific community.

References

Cifani C, Micioni V, Vitale G, Ruggieri V, Ciccocioppo R, Massi M (2010) Effect of salidroside, active principle of Rhodiola rosea extract, on binge eating. 101(5), 555-562.

Yousef GG, Grace MH, Cheng DM, Belolipov IV, Raskin I, Lila MA (2006) Comparative phytochemical characterization of three Rhodiola species. 67(21), 2380-2391.

A. Panossian, G. Wikman, J. Sarris (2010) Rosenroot (Rhodiola rosea): Traditional use, chemical composition, pharmacology and clinical efficacy. 17(7), 481-493.

Daphne Van Diermen, Andrew Marston, Juan Bravo, Marianne Reist, Pierre-Alain Carrupt, Kurt Hostettmann (2009) Monoamine oxidase inhibition by Rhodiola rosea L. roots. 122(2), 397-401. https://doi.org/10.1016/j.jep.2009.01.007

Ma YC, Wang XQ, Hou F, Ma J, Luo M, Lu S (2011) Simultaneous quantification of polyherbal formulations containing Rhodiola rosea L. and Eleutherococcus senticosus Maxim. using rapid resolution liquid chromatography (RRLC). 55(5), 908-915.

D. O'Mathuna (2008) Rhodiola Rosea (Roseroot) for Generalized Anxiety, Depression, and Fatigue. 11, 73-75.

Tsering T, Bai Z, Nan P, Tsering Q, Lei Y, Liu J (2007) Chemical composition of the essential oils of three Rhodiola species from Tibet. 43(6), 716-718.

Korány Héthelyi ÉB, Domokos Galambosi B, Pálinkás J (2005) Chemical Composition of the Essential Oil from Rhizomes ofRhodiola roseaL. Grown in Finland. 17(6), 628-629.

Gupta V, Lahiri S, Sultana S, Kumar R (2009) Mechanism of action of Rhodiola imbricata Edgew during exposure to cold, hypoxia and restraint (C-H-R) stress induced hypothermia and post stress recovery in rats. 47(6), 1239-1245.

Schriner SE, Abrahamyan A, Avanessian A, Bussel I, Maler S, Gazarian M (2009) Decreased mitochondrial superoxide levels and enhanced protection against paraquat inDrosophilamelanogastersupplemented with Rhodiola rosea. 43(9), 836-843.

Leung SB, Zhang H, Lau CW, Huang Y, Lin Z (2013) Salidroside improves homocysteine-induced endothelial dysfunction by reducing oxidative stress.

Chen TS, Liou SY, Chang YL (2008) Antioxidant Evaluation of Three Adaptogen Extracts. 36(6), 1209-1217.

Qian EW, Ge DT, Kong SK (2011) Salidroside promotes erythropoiesis and protects erythroblasts against oxidative stress by up-regulating glutathione peroxidase and thioredoxin. 133(2), 308-314.

Adaptogen APP (2001) Rhodiola rosea: a possible plant adaptogen. 6(3), 293-302.

Mishra KP, Padwad YS, Dutta A, Ganju L, Sairam M, Banerjee PK (2008) Aqueous extract of Rhodiola imbricata rhizome inhibits proliferation of an erythroleukemic cell line K-562 by inducing apoptosis and cell cycle arrest at G2/M phase. 213(2), 125-131.

Majewska A, Grażyna H, Mirosława F, Natalia U, Agnieszka P, Alicja Z (2006) Antiproliferative and antimitotic effect, S phase accumulation and induction of apoptosis and necrosis after treatment of extract from Rhodiola rosea rhizomes on HL-60 cells. 103(1), 43-52. https://doi.org/10.1016/j.jep.2005.05.051

Xiaolan Hu, Shuxin Lin, Daihua Yu, Shuifeng Qiu, Xianqi Zhang, Ruhuan Mei (2010) A preliminary study: the anti-proliferation effect of salidroside on different human cancer cell lines. 26(6), 499-507. https://doi.org/10.1007/s10565-010-9159-1

Hu X, Zhang X, Qiu S, Yu D, Lin S (2010) Salidroside induces cell-cycle arrest and apoptosis in human breast cancer cells. 398(1), 62-67.

Zubeldia JM, Nabi HA, del MJ, Genovese J (2010) Exploring New Applications for Rhodiola rosea : Can We Improve the Quality of Life of Patients with Short-Term Hypothyroidism Induced by Hormone Withdrawal?. 13(6), 1287-1292.

Qu ZQ, Zhou Y, Zeng YS, Lin YK, Li Y, Zhong ZQ (2012) Protective effects of a Rhodiola crenulata extract and salidroside on hippocampal neurogenesis against streptozotocin-induced neural injury in the rat. 7(1), e29641. https://doi.org/10.1371/journal.pone.0029641

Zhang L, Yu H, Zhao X, Lin X, Tan C, Cao G (2010) Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells. 57(5), 547-555.

Alexander Panossian, Marina Hambardzumyan, Areg Hovhanissyan, Georg Wikman (2007) Panossian A, Hambardzumyan M, Hovhanissyan A, Wikman G. The adaptogens Rhodiola and Schizandra modify the response to immobilization stress in rabbits by suppressing the increase of phosphorylated stress-activated protein kinase, nitric oxide and cortisol. 2, 117739280700200. https://doi.org/10.1177/117739280700200011

M. Buckley (2012) Buckley MS. Concentration and mental performance amplifying formulation. U.S. 2012, 409.

Alexander Panossian, Georg Wikman, Punit Kaur, Alexzander Asea (2012) Panossian A, Wikman G, Kaur P, Asea A. Adaptogens stimulate neuropeptide Y and Hsp72 expression and release in neuroglia cells. 6, 6. https://doi.org/10.3389/fnins.2012.00006

G. Aslanyan, E. Amroyan, E. Gabrielyan, M. Nylander, G. Wikman, A. Panossian (2010) Double-blind, placebo-controlled, randomised study of single dose effects of ADAPT-232 on cognitive functions. 17(7), 494-499.

Shun-Wan Chan (2012) Panax ginseng Rhodiola roseaand Schisandra chinensis. 63(sup1), 75-81. https://doi.org/10.3109/09637486.2011.627840

Iovieno N, Dalton ED, Fava M, Mischoulon D (2011) Second-tier natural antidepressants: Review and critique. 130(3), 343-357.

V. Darbinyan, G. Aslanyan, E. Amroyan, E. Gabrielyan, C. Malmström, A. Panossian (2007) Clinical trial ofRhodiola roseaL. extract SHR-5 in the treatment of mild to moderate depression. 61(5), 343-348.

(2008) Rhodiola rosea for general anxiety disorder 2008. http://search.proquest.com/docview/758850739?accountid=2200

Lee Y, Jung JC, Jang S, Kim J, Ali Z, Khan IA, Oh S (2013) Anti-inflammatory and neuroprotective effects of constituents isolated from Rhodiola rosea.

Jeong HJ, Ryu YB, Park SJ, Kim JH, Kwon HJ, Kim JH (2009) Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities. 17(19), 6816-6823.

Wang H, Ding Y, Zhou J, Sun X, Wang S (2009) The in vitro and in vivo antiviral effects of salidroside from Rhodiola rosea L. against coxsackievirus B3. 16(2), 146-155.

Chiang-Shan Niu, Li-Jen Chen, Ho-Shan Niu (2014) Niu CS, Chen LJ, Niu HS. Antihyperglycemic action of rhodiola-aqeous extract in type1-like diabetic rats. 14(1), 20. https://doi.org/10.1186/1472-6882-14-20

Kim SH, Hyun SH, Choung SY (2006) Antioxidative effects of Cinnamomi cassiae and Rhodiola rosea extracts in liver of diabetic mice. 26(3), 209-219.

Fac Wiegant, S. Surinova, E. Ytsma, M. Langelaar-Makkinje, G. Wikman, J. Post (2009) Plant adaptogens increase lifespan and stress resistance in C. elegans. 10(1), 27-42. https://doi.org/10.1007/s10522-008-9151-9

Dmytro Gospodaryov, Ihor Yurkevych, Mahtab Jafari, Volodymyr Lushchak, Oleh Lushchak (2013) Gospodaryov DV, Yurkevych IS, Jafari M, Lushchak VI, Lushchak OV. Lifespan extension and delay of age-related functional decline caused by Rhodiola rosea depends on dietary macronutrient balance. 2(1), 5. https://doi.org/10.1186/2046-2395-2-5

C. Cifani, M. D.B., G. Vitale, M. Massi (2010) Cifani C, DB M, Vitale G, Massi M. Effect of Rhodiola rosea extracts on binge eating in female rats. 54(3), 639. https://doi.org/10.1016/j.appet.2010.04.044

Mattioli L, Perfumi M (2007) Rhodiola rosea L. extract reduces stress- and CRF-induced anorexia in rats. 21(7), 742-750.

E. Bocharov, I. Ivanova-Smolenskaya, V. Poleshchuk, V. Kucheryanu, V. Il'enko, O. Bocharova (2010) Therapeutic Efficacy of the Neuroprotective Plant Adaptogen in Neurodegenerative Disease (Parkinson's Disease as an Example). 149(6), 682-684.

Sana Ishaque, Larissa Shamseer, Cecilia Bukutu, Sunita Vohra (2012) Ishaque S, Shamseer L, Bukutu C, Vohra S. Rhodiola rosea for physical and mental fatigue: a systematic review. 12(1), 70. https://doi.org/10.1186/1472-6882-12-70

Rhodiola rosea from the Selection of Traditional Applications to the Novel Phytotherapy for the Prevention and Treatment of Serious Diseases.

Published

2015-05-27

How to Cite

Rhodiola rosea from the Selection of Traditional Applications to the Novel Phytotherapy for the Prevention and Treatment of Serious Diseases. (2015). Global Journal of Medical Research, 15(18), 1-10. https://medicalresearchjournal.org/index.php/GJMR/article/view/