Latest Insight into the Relation of Metabolic Syndrome with Thyroid Dysfunction

Dr. Ashfaq ul Hassan; Dr. Shazia Nazir

Authors

Dr. Ashfaq ul Hassan
Dr. Shazia Nazir

Keywords:

thyroid, hyperthyroidism, hypothyroidism, subclinical, lipoprotein TRH (thyroid releasing hormone), TSH (thyroid stimulating hormone)

Abstract

The Metabolic syndrome is a modern epidemic and is considrred to be one of the major public health issues of this century. It is constellation of physical conditions and metabolic abnormalities commonly found in association with increased risk for development of Type II diabetes mellitus, cardiovascular disease and other medical conditions. Thyroid hormones play an important role in regulating energy homeostasis. In addition, thyroid hormones can regulate lipoprotein, glucose metabolism and blood pressure. Thus there is possibility of thyroid dysfunction (may be cause or effect) having an association with metabolic syndrome and its component. The study was aimed to find out occurrence of metabolic syndrome in hypothyroid patients and to determine the association between the components of metabolic syndrome and thyroid hypofunction.

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How to Cite

Latest Insight into the Relation of Metabolic Syndrome with Thyroid Dysfunction. (2015). Global Journal of Medical Research, 15(19), 5-12. https://medicalresearchjournal.org/index.php/GJMR/article/view/

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Author Biography

Dr. Ashfaq ul Hassan

Dr. Ashfaq Ul Hassan is a medical researcher and academic affiliated with the Sher-i-Kashmir Institute of Medical Sciences (SKIMS) in Srinagar, India. His work spans anatomy, radiology, and neurosurgery, with published case studies on rare conditions such as internal carotid agenesis, median nerve schwannoma, and open lip schizencephaly with agenesis of the corpus callosum. He has also contributed to research on metabolic syndrome and trauma management. With over 85 publications and 216 citations, Dr. Hassan holds an h-index of 7 and an i10-index of 6, reflecting his ongoing impact in the medical field.

References

Douyon L, Schteingart DE (2002) Effect of obesity and starvation on thyroid hormone, growth hormone and cortisol secretion. 31, 173-89.

Adsani H, Hoffer LJ, silva JE (1997) Resting energy expenditure is sensitive to small dose change in patients with chronic thyroid hormone replacement. 92, 118-125.

Fommei E, Iervasi G (2002) The rore of thyroid hormone in blood pressure homestasis: evidence from shortterm hypothyroidism in humans. 87.

Franklin JA (1994) The management of hyperthyroidism. 330, 19-44.

Clifford Wang, Lawrence Crapo (1997) The epidemiology of thyroid disease and implications for screening Endocrinol Metab Clin North Am. 26(1), 189-218. https://doi.org/10.1016/s0889-8529(05)70240-1

M. Bauer, P. Whybrow (1986) The effect of changing thyroid function on cyclic affective illness in a human subject. 143, 633-636.

Massoudi EN, orchard TJ (1995) Prevalence of thyroid antibodies among healthy middle-aged women. 5, 22-23.

Sakata S, Matsuda M, Ogawa T (1994) Prevalence of thyroid hormone autoantibodies in healthy subjects. 41, 365-370.

McDermott MT, Ridgway EC (2001) Subclinical hypothyroidism is mild thyroid failure and should be treated. 86, 4585-90.

Surk SMI, Ocampo E (1996) Subclinical thyroid disease. 100, 217-223.

Goswami b, V. Gupta, V. Mallika (2008) Evaluation of lipid profile in hypothyroid patients Our experience. 5, 43-47.

Razvi S, Ingoe L, Keeka G, Oates C, McMillan C, Weaver JU (2007) The beneficial effect of L-thyroxin on cardiovascular risk factors, endothelial function, and quality of life in subclinical hypothyroidism: randomized, crossover trial. 92, 1715-23.

David Cooper (2001) Subclinical hypothyroidism N Engl J Med. 345(4), 260-265. https://doi.org/10.1056/nejm200107263450406

T. Serum (2002) Serum TSH, T 4 , and Thyroid Antibodies in the United States Population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). 87, 489-499.

V. Fatourechi (2004) Subclinical hypothyroidism: when to treat, when to watch, consultant. 44, 533-539.

Surks MI, Hollowell JG (2007) Age-specific distribution of serum thyrotropin and antithyroid antibodies in the US population: implications for the prevalence of subclinical hypothyroidism. 92, 4575-82.

Chu JW, Crapo LM (2001) The treatment of subclinical hypothyroidism is seldom necessary. 86(10), 4591-99.

V. Fatourechi, G. Klee, S. Grebe (2003) Effects of reducing the upper limit of normal TSH values [letter]. 290(24), 3195-a-3196. https://doi.org/10.1001/jama.290.24.3195-b