Drug Treatment of Cerebral Vasospasm after Subarachnoid Hemorrhage Following Aneurysms

Authors

  • Yong-Fei Liu

  • Juan Su

  • Wei-Jian Jiang

Keywords:

cerebral vasospasm, subarachnoid hemorrhage, aneurysms, drug treatment

Abstract

Cerebral vasospasm (CVS) is a common and severe complication of aneurysmal subarachnoid hemorrhage (aSAH). Despite the improvement in treatment of aSAH, CVS complicating aSAH has remained the main cause of death. CVS begins most often on the third day after the ictal event and reaches the maximum on the 5th-7th postictal days. Several therapeutic modalities have been employed to prevent or reverse CVS. The aim of this review is to emphatically introduce some kind of pharmacological agent for vasospasm.

How to Cite

Drug Treatment of Cerebral Vasospasm after Subarachnoid Hemorrhage Following Aneurysms. (2016). Global Journal of Medical Research, 16(16), 11-20. https://medicalresearchjournal.org/index.php/GJMR/article/view/

References

Bederson JB, Connolly EJ, Batjer HH, Dacey RG, Dion JE, Diringer MN (2009) Guidelines for the management of aneurysmal subarachnoid hemorrhage: A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association Stroke. 40, 994-1025.

C. Lovelock, G. Rinkel, P. Rothwell (2010) Time trends in outcome of subarachnoid hemorrhage: Populationbased study and systematic review Neurology. 74, 1494-1501.

Murayama Y, Malisch T, Guglielmi G, Mawad ME, Vinuela F, Duckwiler GR (1997) Incidence of cerebral vasospasm after endovascular treatment of acutely ruptured aneurysms: Report on 69 cases. 87, 830-835.

K. Yalamanchili, R. Rosenwasser, J. Thomas, K. Liebman, C. McMorrow, P. Gannon (1998) Frequency of cerebral vasospasm in patients treated with endovascular occlusion of intracranial aneurysms AJNR Am J Neuroradiol. 19, 553-558.

Charpentier C, Audibert G, Guillemin F, Civit T, Ducrocq X, Bracard S (1999) Multivariate analysis of predictors of cerebral vasospasm occurrence after aneurysmal subarachnoid hemorrhage Stroke. 30(7), 1402-1408. https://doi.org/10.1161/01.str.30.7.1402

Salah Keyrouz, Michael Diringer (2007) Keyrouz SG, Diringer MN. Clinical review: Prevention and therapy of vasospasm in subarachnoid hemorrhage. 11(4), 220. https://doi.org/10.1186/cc5958

Castanares-Zapatero D, Hantson P (2011) Pharmacological treatment of delayed cerebral ischemia and vasospasm in subarachnoid hemorrhage.

Gregory Velat, Matthew Kimball, J. Mocco, Brian Hoh (2011) Vasospasm after aneurysmal subarachnoid hemorrhage: Review of randomized controlled trials and meta-analyses in the literature World Neurosurg. 76(5), 446-454. https://doi.org/10.1016/j.wneu.2011.02.030

Amanda Raya, Michael Diringer (2014) Treatment of subarachnoid hemorrhage Crit Care Clin. 30(4), 719-733. https://doi.org/10.1016/j.ccc.2014.06.004

Alejandro Rabinstein, Giuseppe Lanzino, Eelco Wijdicks (2010) Multidisciplinary management and emerging therapeutic strategies in aneurysmal subarachnoid haemorrhage Lancet Neurol. 9(5), 504-519. https://doi.org/10.1016/s1474-4422(10)70087-9

Meghan MacKenzie, Sean Gorman, Steve Doucette, Robert Green (2014) Incidence of and factors associated with manipulation of nimodipine dosage in patients with aneurysmal subarachnoid hemorrhage Can J Hosp Pharm. 67(5), 358-365. https://doi.org/10.4212/cjhp.v67i5.1390

Hänggi D, Perrin J, Eicker S, Beseoglu K, Etminan N, Kamp MA (2012) Local delivery of nimodipine by Prolonged-Release microparticles-feasibility, effectiveness and Dose-Finding in experimental subarachnoid hemorrhage. 7(9), e42597. https://doi.org/10.1371/journal.pone.0042597

Ott S, Jedlicka S, Wolf S, Peter M, Pudenz C, Merker P (2014) Continuous selective intra-arterial application of nimodipine in refractory cerebral vasospasm due to aneurysmal subarachnoid hemorrhage. 2014, 970741. https://doi.org/10.1155/2014/970741

Kronvall E, Undren P, Romner B, Saveland H, Cronqvist M, Nilsson OG (2009) Nimodipine in aneurysmal subarachnoid hemorrhage: A randomized study of intravenous or peroral administration J Neurosurg. 110(1), 58-63. https://doi.org/10.3171/2008.7.jns08178

Onal MB, Civelek E, Kircelli A, Solmaz I, Ugurel S, Narin F (2011) Comparison of nimodipine delivery routes in cerebral vasospasm after subarachnoid hemorrhage: An experimental study in rabbits Acta Neurochir Suppl. 110, 23-28. https://doi.org/10.1007/978-3-7091-0356-2

Fei Wang, Yu-Hua Yin, Feng Jia, Ji-Yao Jiang (2013) Effects of Topical Administration of Nimodipine on Cerebral Blood Flow following Subarachnoid Hemorrhage in Pigs Journal of Neurotrauma. 30(7), 591-596. https://doi.org/10.1089/neu.2009.0890

Brian Hoh, Christopher Ogilvy (2005) Endovascular treatment of cerebral vasospasm: Transluminal balloon angioplasty, intra-arterial papaverine, and intraarterial nicardipine Neurosurg Clin N Am. 16(3), 501-516. https://doi.org/10.1016/j.nec.2005.04.004

Ren-Qiang Huang, Fu-Gang Jiang, Zi-Min Feng, Tian-Yi Wang (2013) Nicardipine in the treatment of aneurysmal subarachnoid haemorrhage: A meta-analysis of published data Acta Neurologica Belgica. 113(1), 3-6. https://doi.org/10.1007/s13760-012-0142-x

Jun P, Ko NU, English JD, Dowd CF, Halbach VV, Higashida RT (2010) Endovascular treatment of medically refractory cerebral vasospasm following aneurysmal subarachnoid hemorrhage. 31(10). https://doi.org/10.3174/ajnr.a2183

Stuart RM, Helbok R, Kurtz P, Schmidt M, Fernandez L, Lee K (2011) High-dose intra-arterial verapamil for the treatment of cerebral vasospasm after subarachnoid hemorrhage: Prolonged effects on hemodynamic parameters and brain metabolism Neurosurgery. 68(2), 337-345. https://doi.org/10.1227/neu.0b013e318201be47

Alana Flexman, Christopher Ryerson, Pekka Talke (2012) Hemodynamic stability after intraarterial injection of verapamil for cerebral vasospasm Anesthesia & Analgesia. 114(6), 1292-1296. https://doi.org/10.1213/ane.0b013e31824d50e8

Mikeladze KG, Eliava S, Shekhtman OD, Lubnin A, Tabasaranskii TF, Iakovlev SB (2013) Intra-arterial injection of verapamil in treatment of cerebral vasospasm in a patient with acute subarachnoid hemorrhage from an aneurysm: Case report Zh Vopr Neirokhir Im N N Burdenko. 77, 57-60.

Janine Keuskamp, Raj Murali, Kuo Chao (2008) High-dose intraarterial verapamil in the treatment of cerebral vasospasm after aneurysmal subarachnoid hemorrhage J Neurosurg. 108(3), 458-463. https://doi.org/10.3171/jns/2008/108/3/0458

Carl Muroi, Martin Seule, Kenichi Mishima, Emanuela Keller (2012) Novel treatments for vasospasm after subarachnoid hemorrhage Current Opinion in Critical Care. 18(2), 119-126. https://doi.org/10.1097/mcc.0b013e32835075ae

Clemens Schirmer, Daniel Hoit, Adel Malek (2008) Schirmer CM, Hoit DA, Malek AM. Iatrogenic vasospasm in carotid artery stent angioplasty with distal protection devices. 24(2), E12.

Satoh S, Takayasu M, Kawasaki K, Ikegaki I, Hitomi A, Yano K (2012) Antivasospastic effects of hydroxyfasudil, a Rho-Kinase inhibitor, after subarachnoid hemorrhage Journal of Pharmacological Sciences. 118(1), 92-98. https://doi.org/10.1254/jphs.11075fp

Masato Naraoka, Akira Munakata, Naoya Matsuda, Norihito Shimamura, Hiroki Ohkuma (2013) Suppression of the Rho/Rho-kinase pathway and prevention of cerebral vasospasm by combination treatment with statin and fasudil after subarachnoid hemorrhage in rabbit Transl Stroke Res. 4(3), 368-374. https://doi.org/10.1007/s12975-012-0247-9

Liu GJ, Wang ZJ, Wang YF, Xu LL, Wang XL, Liu Y (2012) Systematic assessment and meta-analysis of the efficacy and safety of fasudil in the treatment of cerebral vasospasm in patients with subarachnoid hemorrhage European Journal of Clinical Pharmacology. 68(2), 131-139. https://doi.org/10.1007/s00228-011-1100-x

Fabio Taccone, Diego Castanares-Zapatero, Daliana Peres-Bota, Jean-Louis Vincent, Jacques Berre', Christian Melot (2010) Cerebral autoregulation is influenced by carbon dioxide levels in patients with septic shock Neurocrit Care. 12(1), 35-42. https://doi.org/10.1007/s12028-009-9289-6

W. van den Bergh, R. Dijkhuizen, G. Rinkel (2004) Potentials of magnesium treatment in subarachnoid haemorrhage Magnes Res. 17, 301-313.

Santiago Ortega-Gutierrez, Stephan Mayer (2010) Is the magnesium era for aneurysmal subarachnoid hemorrhage over? Curr Neurol Neurosci Rep. 10(6), 420-422. https://doi.org/10.1007/s11910-010-0134-2

Drug Treatment of Cerebral Vasospasm after Subarachnoid Hemorrhage Following Aneurysms

Published

2016-05-16

How to Cite

Drug Treatment of Cerebral Vasospasm after Subarachnoid Hemorrhage Following Aneurysms. (2016). Global Journal of Medical Research, 16(16), 11-20. https://medicalresearchjournal.org/index.php/GJMR/article/view/