The Effect of Green Leafy Vegetable Intake on the Incidence of Urothelial Cancers: A Meta-Analysis

Dr. Richard Lee Pollock

Authors

Dr. Richard Lee Pollock

Keywords:

green leafy vegetables; cruciferous vegetables; random effect model; effect size; forest plot; meta-analysis

Abstract

Study objective was to hypothesized that the consumption of green leafy vegetables (GLV), including cruciferous vegetables (CV), significantly reduces the incidence of urothelial cancers. The hypothesis was answered by using the experimental approach of meta-analysis by synthesizing relevant worldwide studies that address the association between the consumption of GLV and risk of incidence of the disease. Three models were used, and the first indicated an overall odds ratio effect size of the 'almost every day' highest vs. lowest quantile intake category of GLV on urothelial cancer as: OR = 0.749 (95% CI .678 to .827), p

Downloads

How to Cite

The Effect of Green Leafy Vegetable Intake on the Incidence of Urothelial Cancers: A Meta-Analysis. (2016). Global Journal of Medical Research, 16(22), 29-36. https://medicalresearchjournal.org/index.php/GJMR/article/view/

Download Citation

References

M. Zeegers, R. Goldbohm, P. van den Brandt (2001) Consumption of vegetables and fruits and urothelial cancer incidence: A prospective study. 10, 1121-1128.

Sakauchi F, Mori M, Mashio M, Watanabe Y, Ozasa K, Hayashi K (2004) Dietary Habits and Risk of Urothelial Cancer Death in a Large-Scale Cohort Study (JACC Study) in Japan. 50(1), 33-39. https://doi.org/10.1207/s15327914nc5001

P. Carter, L. Gray, J. Troughton, K. Khunti, M. Davies (2010) Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis.

Kaumudi Joshipura, A. Ascherio, J. Manson, M. Stampfer, E. Rimm, F. Speizer (1999) Fruit and Vegetable Intake in Relation to Risk of Ischemic Stroke. 282(13), 1233. https://doi.org/10.1001/jama.282.13.1233

Smith-Warner SA, Spiegelman D, Yaun SS, Adami HO, Beeson WL, van P (2001) Intake of fruits and vegetables and risk of breast cancer: A pooled analysis of cohort studies. 285, 769.

J. Higgins, L. Hedges, M. Borenstein, Rothstein HR (2009) Introduction to meta-analysis.

Stigler S. Fisher and the 5% level. 12.

S. Grieb, R. Theis, D. Burr, D. Benardot, T. Siddiqui, N. Asal (2009) Food groups and renal cell carcinoma: Results from a case-control study. 109, 656-667.

Hsu CC, Chow W, Boffetta P, Moore L, Zaridze D, Moukeria A (2007) Dietary Risk Factors for Kidney Cancer in Eastern and Central Europe. 166, 62-63.

Wakai K, Hirose K, Takezaki T, Hamajima N, Ogura Y, Nakamura S (2004) Foods and beverages in relation to urothelial cancer: Case‐control study in Japan. 11, 11-19.

Jinfu Hu, Yang Mao, Kathy White (2003) Diet and vitamin or mineral supplements and risk of renal cell carcinoma in Canada. 14(8), 705-714. https://doi.org/10.1023/a:1026310323882

Brock KE, Ke L, Gridley G, Chiu BC, Ershow AG, Lynch CF (2012) Fruit, vegetables, fibre and micronutrients and risk of US renal cell carcinoma. 108, 1077-1085.

(2009) Introduction to meta-analysis (statistics in practice).

Park S, Ollberding NJ, Woolcott CG, Wilkens LR, Henderson BE, Kolonel LN (2013) Fruit and Vegetable Intakes Are Associated with Lower Risk of Bladder Cancer among Women in the Multiethnic Cohort Study1,2. 143, 1283-1292. https://doi.org/10.3945/jn.113.174920

Ros MM, Bueno-de-Mesquita HB, Kampman E, Buchner FL, Aben KK, Egevad L (2012) Fruit and vegetable consumption and risk of aggressive and non-aggressive urothelial cell carcinomas in the European Prospective Investigation into Cancer and Nutrition. 48(17), 3267-3277. https://doi.org/10.1016/j.ejca.2012.05.026

Tang L, Zirpoli GR, Guru K, Moysich KB, Zhang Y, Ambrosone CB, McMann SE (2010) Intake of cruciferous vegetables modifies bladder cancer survival Cancer Epidemiol Biomarkers Prev. 19(7), 1806-1811. https://doi.org/10.1158/1055-9965.epi-10-0008

M. Zeegers, R. Goldbohm, P. van den Brandt, N. Kurahashi, M. Inoue, M. Iwasaki, Y. Tanaka, M. Mizokami, S. Tsugane (2009) Consumption of vegetables and fruits and urothelial 27 Kurahashi N, Inoue M, Iwasaki M, Tanaka Y, Mizokami M, Tsugane S Vegetable, fruit and antioxidant nutrient consumption and subsequent risk of hepatocellular carcinoma: A prospective cohort study in Japan. 100, 181-184.

L. DeBruyne, K. Pinna, E. Whitney (2011) Nutrition & diet therapy.