Abstract

In this paper Neuro-dynamic programming NDP is proposed as an alternative to alleviate the curse of dimensionality of the Dynamic programming DP for optimal control of a fed-batch fermentation process in the L-lysine production The most effective and cheapest method for the Llysine biosynthesis in biological active form is the microbiological method via a direct fermentation In this paper an optimization method of the L-lysine production from strain Brevibacterium flavum 22LD is used and that is NDP The results show that the quality of L-lysine enhances at the end of the process The proposed method is particularly simple to implement and can be applied for on-line optimization