Incidence of Carcinoma of the Prostate in Patients with Normal Prostatic Specific Antigen Following Prostatectomy

Elaimam Ibrahim Mohmmed Elaimam

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Elaimam Ibrahim Mohmmed Elaimam

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Abstract

Background/Aims: Prostate cancer is fourth most common male cancer, recent data showed an increased incidence among Sudanese males and it is becoming a major medical problems and gained increased attention from Sudanese urologists. Objective: To detect patients with prostate cancer, in prostatectomy specimens, with normal preoperative PSA levels. To try to suggest a base line level of PSA above which prostatectomy should not be performed unless having a histological tissue diagnosis. Materials and methods: This is descriptive, prospective cross sectional, hospital based study, conducted at Soba University Hospital, Omdurman Military Hospital, Ibn Sina specialized Hospital in the period from September 2012 to August 2013 All patients above 40 years of age undergoing prostectomy with normal PSA levels in the above mentioned hospitals were enrolled in this study, their surgical specimens was sent for histology. Results: The PSA level was below 4 ng/ml in all cases, with a mean of 1.85 ng/dl (total), and 0.36 ng/dl free PSA. The histology of the prostatectomy specimens showed adenocarcinoma in 14 Pts (13.1%) and BPH in 93 pts (86.7%). Conclusion: There was a detection rate of (13.1%) among patients with PSA below ng/ml, with high grade Gleason scores. Suspicious DRE in low PSA patients enhances the cancer detection rate.

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Incidence of Carcinoma of the Prostate in Patients with Normal Prostatic Specific Antigen Following Prostatectomy. (2013). Global Journal of Medical Research, 13(17), 25-29. https://medicalresearchjournal.org/index.php/GJMR/article/view/

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Author Biography

Elaimam Ibrahim Mohmmed Elaimam

Elaimam Ibrahim Mohmmed Elaimam is a medical researcher affiliated with the Sudan Medical Specialization Board (SMSB) in Sudan. His work focuses on urological oncology, particularly the incidence of prostate carcinoma in patients with normal prostate-specific antigen levels following prostatectomy. With a single publication to date, his research contributes to the understanding of prostate cancer diagnosis and management in the Sudanese context.

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