Integrating Network Pharmacology and Molecular Docking to Identify the Active Substances and Mechanisms of Chrysanthemum Against Dry Eye

Zhang Yanxue; Tang Yu; Wu Kai; Yao Xiaolei

doi:10.34257/GJMRBVOL24IS1PG1

Authors

Zhang Yanxue
Tang Yu
Wu Kai
Yao Xiaolei

Keywords:

chrysanthemum, dry eye, chinese medicine, network pharmacology, molecular docking

Abstract

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Integrating Network Pharmacology and Molecular Docking to Identify the Active Substances and Mechanisms of Chrysanthemum Against Dry Eye. (2024). Global Journal of Medical Research, 24(B1), 1-13. https://doi.org/10.34257/GJMRBVOL24IS1PG1

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References

P Rouen, M White (2018) Dry Eye Disease: Prevalence, Assessment, and Management. 36(2), 74-83.

Kimberly Farrand, Moshe Fridman, Ipek Stillman, Debra Schaumberg (2017) Prevalence of Diagnosed Dry Eye Disease in the United States Among Adults Aged 18 Years and Older. 182, 90-98.

Leisa Marshall, J Roach (2016) Treatment of Dry Eye Disease. 31(2), 96-106.

F Lozano (2014) Basic Theories of Traditional Chinese Medicine. 13-43.

San-Hua Su, Tsung-Jung Ho, Cheng-Chan Yang (2021) Retrospective evaluation of the curative effect of traditional Chinese medicine on dry eye disease. 33(4), 365-369.

Huiyuan Tan, Guangyao Li, Qiumei Ruan, Chuanghui Yang, Xuelian Ma, Min Li (2021) Acupuncture combined with traditional Chinese medicine for dry eye: A systematic review and meta-analysis. 31(2), 152-156.

C Ou, Q Peng, X Chen (2019) A brief analysis of the treatment of dry eyes from the "Shen Shi Yao Han. 30(04), 1025-1026.

Liu Mengling, Zhang Xinyou, Ding Liang, Wu Shumao, Li Diyao, Xiuyun (2021) Data integration, data mining and visualization analysis of traditional Chinese medicine manufacturing process. 46(20), 5233-5239.

Junfei Zhang, Xinjun Wang, Yu Zhong, Shuming Gao, Lichao Zhang, Diwen Fan, Cong Zhou, Senlin Wang (2017) Optimization Design Method of Variable-Period TPMS Structures Based on Period Tensor. 42(21), 4054-4058.

Chen Shi Jian, Liu Lihao, Peng Qianhong, Tang Jun, Yao Yu, Liu Xiaolei, Guoguo (2020) Inflammatory Mechanism of Total Flavonoids of Chrysanthemum and Medicated Serum on Castrated Dry Eye Animal and Cell Models. 3(4), 283-296.

Won-Yung Lee, Choong-Yeol Lee, Youn-Sub Kim, Chang-Eop Kim (2019) The Methodological Trends of Traditional Herbal Medicine Employing Network Pharmacology. 9(8), 362.

Y Li, P Yang, Y Luo, B Gao, J Sun, W Lu, J Liu, P Chen, Y Zhang, L Yu (2019) Chemical compositions of chrysanthemum teas and their anti-inflammatory and antioxidant properties. 286, 8-16.

S Chen, J Liu, G Dong, X Zhang, Y Liu, W Sun, A Liu (2021) Flavonoids and caffeoylquinic acids in Chrysanthemum morifolium Ramat flowers: A potentially rich source of bioactive compounds. 344, 128733.

Hanwen Yuan, Sai Jiang, Yingkai Liu, Muhammad Daniyal, Yuqing Jian, Caiyun Peng, Jianliang Shen, Shifeng Liu, Wei Wang (2020) The flower head of Chrysanthemum morifolium Ramat. (Juhua): A paradigm of flowers serving as Chinese dietary herbal medicine. 261, 113043.

J Ru, P Li, J Wang, W Zhou, B Li, C Huang, P Li, Z Guo, W Tao, Y Yang (2014) TCMSP: a database of systems pharmacology for drug discovery from herbal medicines. 6, 13.

G Stelzer, I Dalah, T Stein, Y Satanower, N Rosen, N Nativ, D Oz-Levi, T Olender, F Belinky, I Bahir (2011) In-silico human genomics with GeneCards. 5(6), 709-717.

Michael Kohl, Sebastian Wiese, Bettina Warscheid (2011) Cytoscape: Software for Visualization and Analysis of Biological Networks. 696, 291-303.

Damian Szklarczyk, Annika Gable, David Lyon, Alexander Junge, Stefan Wyder, Jaime Huerta-Cepas, Milan Simonovic, Nadezhda Doncheva, John Morris, Peer Bork, Lars Jensen, Christian Mering (2019) STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets. 47(D1), D607-D613.

Juntao Kan, Min Wang, Ying Liu, Hongyue Liu, Liang Chen, Xue Zhang, Chengrong Huang, Bryan Liu, Zhensheng Gu, Jun Du (2020) A novel botanical formula improves eye fatigue and dry eye: a randomized, double-blind, placebo-controlled study. 112(2), 334-342.

N Erdinest, A Solomon (2019) TOPICAL ANTI-INFLAMMATORY AGENTS FOR DRY EYE DISEASE. 158(2), 130-135.

Y Wei, P Asbell (2014) The core mechanism of dry eye disease is inflammation. 40(4), 248-256.

Laura Periman, Victor Perez, Daniel Saban, Meng Lin, Piergiorgio Neri (2020) The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options. 36(3), 137-146.

Y Uchino, T Kawakita, M Miyazawa, T Ishii, H Onouchi, K Yasuda, Y Ogawa, S Shimmura, N Ishii, K Tsubota (2012) Oxidative stress induced inflammation initiates functional decline of tear production. 7(10), 45805.

Gabriele Carullo, Anna Cappello, Luca Frattaruolo, Mariateresa Badolato, Biagio Armentano, Francesca Aiello (2017) Quercetin and Derivatives: Useful Tools in Inflammation and Pain Management. 9(1), 79-93.

H Oh, C Kim, J Lee, J Yang (2015) Effects of Quercetin in a Mouse Model of Experimental Dry Eye. 34(9), 1130-1136.

Tina Mckay, Dimitrios Karamichos (2017) Quercetin and the ocular surface: What we know and where we are going. 242(6), 565-572.

Chaobin Lin, Fujin Wu, Tongmei Zheng, Xiuchun Wang, Yiwei Chen, Xiaomin Wu (2019) Kaempferol attenuates retinal ganglion cell death by suppressing NLRP1/NLRP3 inflammasomes and caspase-8 via JNK and NF-κB pathways in acute glaucoma. 33(5), 777-784.

H Chen, Z Chen, T Wang, V Drew, C Tseng, H Fang, F Lin (2017) Herbal Supplement in a Buffer for Dry Eye Syndrome Treatment. 18(8).

K Kanai, T Hatta, S Nagata, Y Sugiura, K Sato, Y Yamashita, Y Kimura, N Itoh (2016) Luteolin attenuates endotoxin-induced uveitis in Lewis rats. 78(8), 1229-1235.

S Singh, P Gupta, A Meena, S Luqman (2020) Acacetin, a flavone with diverse therapeutic potential in cancer, inflammation, infections and other metabolic disorders. 145, 111708.

Hao Wang, Zengxin Jiang, Zhiying Pang, Tianyao Zhou, Yutong Gu (2020)

Acacetin Alleviates Inflammation and Matrix Degradation in Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration in vivo

. Volume 14, 4801-4813.

M Dogru, T Kojima, C Simsek, K Tsubota (2018) Potential Role of Oxidative Stress in Ocular Surface Inflammation and Dry Eye Disease. 59(14), 163-168.

Xiaoyun Ma, Jun Zou, Linping He, Yun Zhang (2014) Dry eye management in a Sjögren's syndrome mouse model by inhibition of p38-MAPK pathway. 9(1), 5.

Luca Pinzi, Giulio Rastelli (2019) Molecular Docking: Shifting Paradigms in Drug Discovery. 20(18), 4331.

K Garbutcheon-Singh, N Carnt, U Pattamatta, C Samarawickrama, A White, V Calder (2019) A Review of the Cytokine IL-17 in Ocular Surface and Corneal Disease. 44(1), 1-10.

Xin-Gang Nie, Dong-Sheng Fan, Yan-Xia Huang, Ying-Ying He, Bo-Li Dong, Feng Gao (2018) Downregulation of microRNA-149 in retinal ganglion cells suppresses apoptosis through activation of the PI3K/Akt signaling pathway in mice with glaucoma. 315(6), C839-C849.

Amandine Charras, Pinelopi Arvaniti, Christelle Le Dantec, Marina Arleevskaya, Kaliopi Zachou, George Dalekos, Anne Bordon, Yves Renaudineau (2020) JAK Inhibitors Suppress Innate Epigenetic Reprogramming: a Promise for Patients with Sjögren's Syndrome. 58(2), 182-193.

Miaomiao Xin, Hongda Liang, Hongyue Wang, Dawei Wen, Liqin Wang, Lei Zhao, Mingshu Sun, Jibo Wang (2019) RETRACTED ARTICLE: Mirt2 functions in synergy with miR-377 to participate in inflammatory pathophysiology of Sjögren's syndrome. 47(1), 2473-2480.

D Zhang, Y Zhao, Y Yang, Y Zhao, D Wu, X Liu, Z Shi, J Hong, J Liu, X Ma (2020) A Mechanism Study of Electroacupuncture for Dry Eye Syndrome by Targeting Conjunctival Cytokine Expressions. 45(4), 419-427.

Ji Min, Chul Lee, Yong Ji, Areum Yeo, Hyemi Noh, Insil Song, Eung Kim, Hyung Lee (2016) Activation of Dll4/Notch Signaling and Hypoxia-Inducible Factor-1 Alpha Facilitates Lymphangiogenesis in Lacrimal Glands in Dry Eye. 11(2), e0147846.

Yong Ji, Joon Lee, Eun Choi, Hyun Kang, Kyoung Seo, Jong Song, Hyeon Kim, Hyung Lee (2020) HIF1α-mediated TRAIL Expression Regulates Lacrimal Gland Inflammation in Dry Eye Disease. 61(1), 3.