Study of Weekly Paclitaxel with Concurrent Radiotherapy V/S Weekly Cisplatin with Concurrent Radiotherapy in Advanced Cervix Carcinoma
Abstract
Purpose: To evaluate the Response and Efficacy of weekly paclitaxel with concurrent radiotherapy in comparison to weekly cislatin with concurrent radiotherapy in advanced cervical cancer patients. Methods: Patients coming to the department of radiotherapy S.M.S Hospital were included in the study.50 patients of advanced squamous cell carcinoma of cervix FIGO stage III &IV were selected. In the study and control group , patients were given 5 weeks of external beam radiotherapy followed by brachytherapy. External beam irradiation each of 200 c Gy/fr, on linear acceleretor by parallel opposed - anterior and posterior fields was given. External beam irradiation was followed by Intracavitary brachytherapy 700 c Gy/week for 3 weeks each with High Dose Rate Iridium 192 source. Patients received 50 Gy by External beam irradiation (200 c Gy/fr, total
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References
Kounteya Sinha (2005) Principles and practice of Gynecologic oncology.
Kvale G, Heuch I, Ursin G (1988) Reproductive factor and risk of cancer of the uterine corpus: A prospective study. 48, 6217.
Sankaranarayanan R, Esmy PO, Raj R Visual Screening and Cervical Cancer. 20.
(2010) The Times of India 2012-10-21: Dr. Surendra S. 11.
Keys HM, Bundy BN, Stehman FB (1999) Cisplatin, radiation and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for Bulky stage IB cervical carcinoma. https://doi.org/10.1056/NEJM199904153401503
R. Pearcey, M. Brundage, P. Drouin (2002) Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix. 20(4), 96672. https://doi.org/10.1200/JCO.20.4.966.7
P. Rose (2006) Concurrent chemoradiation for locally advanced carcinoma of the cervix: where are we in 2006?. (Suppl 10).
Chen MD, Paley PJ, Potish RA (1997) Phase I trial of Taxol as radiation sensitizer with Cisplatin in advanced cervical cancer. 67, 131-6.
DiSilvestro PA, Walker JL, Morrison A., Gynecologic Oncology Group (2006) Radiation therapy with concomitant paclitaxel and cisp-latin chemotherapy in cervical carcinoma limited to the pelvis: a phase I/II study of the Gynecologic Oncology Group. 103(3).
New response evaluation criteria in solid tumours.
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2013-12-04
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