Antioxidant Activity of Phenyl Alanine Mandelates by Chemical and Electrochemical Methods

Abstract

Food decomposition in human body due to the redox reactions results in the formation of reactive oxygen species (ROS). ROS obtained during metabolic activitities in our body are responsible for cancerous diseases. ROS are scavenged by hydroxyl radicals present in the small organic molecules. Novel small organic molecules like mandelic acid -amino acid complexes, possess the weak hydrogen bonds and vanderwaals forces of attractions in the complex formation results in the antioxidant property. The title compounds, Rphenyl alanine-Smandelate (RPASMA), Bis-L-phenyl alanine mandelate (BLPAMA) and L-phenyl alanine bis mandelate (BMALPA) are synthesised, carried out characterisation studies like FTIR, NMR, TG-DTA, mass, UV and melting point and grown single crystal by slow evaporation technique confirmed the structure by single crystal XRD. The electrochemical behaviour of the phenyl alanine mandelates show the existence of redox activity using cyclic voltammetry and is confirmed by comparing with the chemical behaviour using DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging method.