Abstract

In this study, autopsy tissues were extracted and cleaned then subjected to TLC using suitable solvent system. A gas chromatographic-mass spectrometric (GC-MS) method is described for the determination of Dicyclomine residue in autopsy tissue. This method allows detection of residual drug in biological tissues by using single-ion monitoring; confirmation by a full scan electron impact (EI) mass spectrum is possible. The aim of the paper is to use the proposed technique in cases of drug trafficking, illicit drug seizures and as a test for identity in pharmaceutical and forensic toxicological analysis. The focus of present study has been on methods for detection