Epidemiology of Staphylococcus spp. with Analysis of Various Available Methods for Detection of Methicillin Resistant Staphylococcus Aureus
Keywords:
Abstract
Staphylococcus aureus is one of the major resistant pathogens in clinical practice; Methicillin Resistant Staphylococcus aureus (MRSA) has come out as superbugs. Apart from this, with the increase in the number of hospitalized immunocompromised patients, Coagulase negative Staphylococcus (CONS) have become a major cause of nosocomial infections. Although molecular method like mecA gene detection is gold standard for MRSA, minimum inhibitory concentration (MIC) of cefoxitin or oxacillin can also be considered as standard where molecular methods are not available. Cefoxitin 30 #x3BC;g disc or PBP 2a agglutination test can also be used as standard marker for MRSA identification. In this study, out of total 184 clinically significant, non-duplicate specimens, 150 (81.52%) isolates were Staphylococcus aureus and 34 (18.48%) were CONS. Among the CONS, the predominating isolate was Staphylococcus haemolyticus 15 (44.12%), followed by Staphylococcus epidermidis 10 (29.41%). In our study, cefoxitin disk diffusion test was found to have sensitivity 100%, specificity 92.15% and negative predictive value (NPV) 100%. PBP2a latex agglutination test was found to have sensitivity 99%, specificity 97.87% and negative predictive value (NPV) 97.87% in our study. In both the methods, MIC of cefoxitin has been considered as gold standard.
Downloads
- Article PDF
- TEI XML Kaleidoscope (download in zip)* (Beta by AI)
- Lens* NISO JATS XML (Beta by AI)
- HTML Kaleidoscope* (Beta by AI)
- DBK XML Kaleidoscope (download in zip)* (Beta by AI)
- LaTeX pdf Kaleidoscope* (Beta by AI)
- EPUB Kaleidoscope* (Beta by AI)
- MD Kaleidoscope* (Beta by AI)
- FO Kaleidoscope* (Beta by AI)
- BIB Kaleidoscope* (Beta by AI)
- LaTeX Kaleidoscope* (Beta by AI)
How to Cite
Published
2020-07-15
Issue
Section
License
Copyright (c) 2020 Authors and Global Journals Private Limited
This work is licensed under a Creative Commons Attribution 4.0 International License.