Case Report on Management of Combined Factor V and factor VIII Deficiency during Pregnancy
Keywords:
autosomal recessive, bleeding disorder, post partum hemorrhage, fresh frozen plasma
Abstract
Combined factor V and factor VIII deficiency (CF5F8D) is a rare autosomal recessive disorder associated with mild to moderate risk of bleeding tendency. These patients have an increased risk of bleeding after surgical procedures. Pregnant women are at increased risk of having a miscarriage, placental abruption, or post partum hemorrhage. Management of these patients requires the replacement of deficient factors. We are reporting a case of management of a 31-year old second gravida female with combined factor V and factor VIII deficiency, who was transfused with fresh frozen plasma before and during labor to prevent bleeding episodes.
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References
Elena Faioni, Gessica Fontana, Giovanni Carpani, Enza D'auria, Giuseppe Banderali, Gianalessandro Moroni, Marco Cattaneo (2003) Review of clinical, biochemical and genetic aspects of combined factor V and factor VIII deficiency, and report of a new affected family. 112(5-6), 269-271.
W Nichols, V Terry, M Wheatley, A Yang, A Zivelin, Ciavarellann (1999) ERGIC-53 gene structure and mutation analysis in 19 combined factors V and VIII deficiency families. 93, 2261-2266.
J Oeri, M Matter, H Isenschmid, F Hauser, F Koller (1954) Congenital factor V deficiency (parahemophilia) with true hemophilia in two brothers. 58, 575-588.
J Giddings, U Seligsohn, A Bloom (1977) Immunological Studies in Combined Factor V and Factor VIII Deficiency. 37(2), 257-264.
B Zhang, B Mcgee, J Yamaoka (2006) Combined deficiency of factor V and factor VIII is due tomutations in either LMAN1 or MCFD2. 107(5), 1903-1907.
Pier Mannucci, Stefano Duga, Flora Peyvandi (2004) Recessively inherited coagulation disorders. 104(5), 1243-1252.
Flora Peyvandi, Marzia Menegatti, Simona Siboni (2011) Post-partum hemorrhage in women with rare bleeding disorders. 127, S116-S119.
Yvonne Stirling, Linda Woolf, W North, M Seghatchian, T Meade (1984) Haemostasis in Normal Pregnancy. 52(02), 176-182.
Katarina Bremme (2003) Haemostatic changes in pregnancy. 16(2), 153-168.
A James (2005) More than menorrhagia: a review of the obstetric and gynaecological manifestations of bleeding disorders. 11(4), 295-307.
P Bolton‐maggs, D Perry, E Chalmers, L Parapia, J Wilde, M Williams, P Collins, S Kitchen, G Dolan, A Mumford (2004) The rare coagulation disorders - review with guidelines for management from the United Kingdom Haemophilia Centre Doctors' Organisation. 10(5), 593-628.
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2021-03-09
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