The Impact of Senna Siamea (Lam) leaves extracts on 2, 2-Dichlorovinyldimethyl Phosphate Induced Brain Oxidative Stress in Wistar Albino Rats
Keywords:
Senna siamea; brain toxicity; oxidative stress; antioxidant properties; #x3B3;-glutamyl transferase
Abstract
Organophosphate compounds have been a common source of mortality in recent times. A typical example is dichlorvos [2, 2-Dichlorovinyldimethylphosphate (DDVP)]; an important agricultural pesticide. This study sought to investigate the phytochemical screening, invitro antioxidant property of the leaf solvents extracts and ameliorating effects of Senna siameain DDVP-induced brain oxidative stress in Wistar rats. The aqueous, methanol and ethanol extracts of the leaves were obtained and analyzed for their in-vitro antioxidant parameters. Thirty-two healthy Wistar albino rats were grouped into eight of 4rats each weighing between 140-150g. The animals were orally administered with 6.6mg/kg body weight of DDVP except groups1 and 2 followed by treatments with the three solvents extracts respectively that lasted for four weeks.
Downloads
- Article PDF
- TEI XML Kaleidoscope (download in zip)* (Beta by AI)
- Lens* NISO JATS XML (Beta by AI)
- HTML Kaleidoscope* (Beta by AI)
- DBK XML Kaleidoscope (download in zip)* (Beta by AI)
- LaTeX pdf Kaleidoscope* (Beta by AI)
- EPUB Kaleidoscope* (Beta by AI)
- MD Kaleidoscope* (Beta by AI)
- FO Kaleidoscope* (Beta by AI)
- BIB Kaleidoscope* (Beta by AI)
- LaTeX Kaleidoscope* (Beta by AI)
How to Cite
References
Aminu Imam, Muhammed Adebayo, Wahab Abdulmajeed, Abdulmusawir Alli-Oluwafuyi, Abdulbasit Amin, Abdulmumin Ibrahim, Sadiya Gwadabe, Niyiabdulgafar Popoola (2018) Dichlorvos Induced AChE Inhibition in Discrete Brain Regions and the Neuro-Cognitive Implications: Ameliorative Effect of Nigella Sativa. 12(5), 11-16.
E Michael, A Nick, E Peter, H Andrew (2008) Management of acute organophosphorus pesticide poisoning. 371, 597-607.
Oluwafemiadeleke Ojo, Babatunjiemmanuel Oyinloye, Basiruolaitan Ajiboye, Adebolabusola Ojo, Habiba Musa, Olaideibiwumi Olarewaju (2014) Dichlorvos-induced oxidative stress in rat brain: Protective effects of the ethanolic extract of Alstonia boonei stem bark. 8(4), 216.
Baz Chedi, M Aliyu (2010) Effect and management of Acute Dichloros poisoning in wistar rats. 3(2), 1-3.
Y Surh (1999) Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. 428, 305-327.
J Winston (1999) Health-promoting properties of common herbs. 70, 491-499.
D Fiorino, D Treit, J Menard, L Termer, A Phillips (1998) Is barakol anxiolytic?. 9(4), 375.
Geerati Sornwattana (2000) Crude barakol extraction from Cassia siamea using packed bed extractor. 22, 429-434.
A Atif, A Naveed, A Barkat, S Muhammad, R Akhtar, U Shahiq-Zaman, K Nayab, W Khalid, M Tariq, A Liaqat (2012) Acacia nilotica: A plant of multipurpose medicinal uses. 6(9), 492-1496.
(2020) Natural Resources Conservation Service PLANTS Database.
G Trease, W Evans (2002) Trease and Evans' Pharmacognosy. 15, 42-393.
A Sofowora (1993) Medicinal Plants and Traditional Medicinal in Africa. 2nd Ed. Sunshine House, Ibadan, Nigeria. 134-156.
Randall Ruch, Shu-Jun Cheng, James Klaunig (1989) Prevention of cytotoxicity and inhibition of intercellular communication by antioxidant catechins isolated from Chinese green tea. 10(6), 1003-1008.
A Shirwaikar A Shirwaikar, K Rajendran, Isj Punitha (2006) In Vitro Antioxidant Studies on the Benzyl Tetra Isoquinoline Alkaloid Berberine. 29(9), 1906-1910.
Laura Green, David Wagner, Joseph Glogowski, Paul Skipper, John Wishnok, Steven Tannenbaum (1982) Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. 126(1), 131-138.
W Brand-Williams, M Cuvelier, C Berset (1995) Use of a free radical method to evaluate antioxidant activity. 28(1), 25-30.
C Winterbourne, R Hawkins, Brain Carrel, R (1975) The estimation of red cell superoxide dismutase activity. 85, 337-341.
V Singleton, Joseph Rossi (1965) Colorimetry of Total Phenolics with Phosphomolybdic-Phosphotungstic Acid Reagents. 16(3), 144-158.
Jia Zhishen, Tang Mengcheng, Wu Jianming (1999) The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. 64(4), 555-559.
(2010) IACUC Oversight of Training and Qualification in Animal Care and Use. 39, 118-131.
Henry Utley, Frederick Bernheim, Paul Hochstein (1967) Effect of sulfhydryl reagents on peroxidation in microsomes. 118(1), 29-32.
Sigma-Aldrich (2013) SuperSite Sigma-Aldrich. 1998(184), 99.
Britton Chance, A Maehly (1955) [136] Assay of catalases and peroxidases. 2, 764-775.
Von Euler, H Josephson, K (1972) European Journal of Organic Chemistry. 452(1), 158-181.
Hara Misra, Irwin Fridovich (1972) The Role of Superoxide Anion in the Autoxidation of Epinephrine and a Simple Assay for Superoxide Dismutase. 247(10), 3170-3175.
William Habig, Michael Pabst, William Jakoby (1974) Glutathione S-Transferases. 249(22), 7130-7139.
Inger Carlberg, Bengt Mannervik (1985) [59] Glutathione reductase. 113, 484-490.
Janardanan Mohandas, Jocelyn Marshall, Geoffrey Duggin, John Horvath, David Tiller (1984) Differential distribution of glutathione and glutathione-related enzymes in rabbit kidney. 33(11), 1801-1807.
D Jollow, J Mitchell, N Zampaglione, J Gillette (1974) Bromobenzene-Induced Liver Necrosis. Protective Role of Glutathione and Evidence for 3,4-Bromobenzene Oxide as the Hepatotoxic Metabolite. 11(3), 151-169.
O Oseni, O Williams (2018) In-vitro compositional investigations of antioxidants, phytochemicals, nutritional and minerals in the fruit of Kigelia africana (Lam.) Benth. 9(8), 20259-20268.
Hemayet Hossain, S Moniruzzaman, Ishrat Nimmi, Hassan Kawsar, Akbor Hossain, Amirul Islam, Ismet Jahan (2012) Anti-inflammatory and antioxidant activities of the ethanolic extract of Ceriops decandra (Griff.) Ding Hou bark. 11(4), 215-220.
Jussi-Pekka Rauha, Susanna Remes, Marina Heinonen, Anu Hopia, Marja Kähkönen, Tytti Kujala, Kalevi Pihlaja, Heikki Vuorela, Pia Vuorela (2000) Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds. 56(1), 3-12.
A Amoussa, A Sanni, L Lagnika (2015) Antioxidant activity and total phenolic, flavonoid and flavonol contents of the bark extracts of Acaciaataxacantha. 4(2), 172-178.
S Asha, P Thirunavukkarasu, V Mani, A Sadiq (2016) Antioxidant Activity of Euphorbia hirta Linn Leaves Extracts. 14(1), 1-14.
A Shalu, G Kulkarni, V Sharma (2010) A Comparative Study on the Antioxidant Activity of Methanol Extracts of Acacia nilotica and Berberis chitria. 4(1), 78-84.
M Jyoti, A Saroj (2013) Safety assessment of the fruit extract of Acacia nilotica Linn. Willd ex Delile using rat models. 10(4), 81-92.
R Choudhary, P Swarnkar (2011) Antioxidant activity of phenolic and flavonoid compounds in some medicinal plants of India. 25(11), 1101-1109.
O Oseni, S Olagboye, A Idowu (2018) Potassium Bromate Induced Renal Toxicity in Wistar Albino Rats: Effects of Aqueous Extract of Nutmeg (Myristica fragrans Houtt). 5(12), 1547-1556.
Praveen Krishnamurthy, Ashish Wadhwani (2012) Antioxidant Enzymes and Human Health. 13-15.
O Oseni, S Olagboye, O Adams, B Maikasuwa (2018) The protective effects of aqueous extract of African nutmeg (Myristicafragrans) in bromateinduced spleen and cardiac tissue toxicities using male wistar albino rats. 8(5), 257-262.
R Uroko, A Agbafor, O Uchenna, N Achi, S Egba, P Nweje-Anyalowu, O Ngwu (2017) Evaluation of Antioxidant Activity of Aqueous Extracts of Palm Fruits (Elaeis guineensis). 12, 49-58.
Samuel Onoja, Yusuf Omeh, Maxwell Ezeja, Martins Chukwu (2014) Evaluation of theIn VitroandIn VivoAntioxidant Potentials ofAframomum meleguetaMethanolic Seed Extract. 2014(-6), 1-6.
M Sani, S Kouhsari, L Moradabadi (2012) Effects of Three Medicinal Plants Extracts in Experimental Diabetes: Antioxidant Enzymes Activities and Plasma Lipids Profiles in Comparison with Metformin. 11(3), 897-903.
(1999) Free Radicals in Biology and Medicine. 105-245.
I Fridovich (1995) Superoxide radical and superoxide dismutases. 64, 97-112.
Henrique Teixeira, Robert Schumacher, Rogerio Meneghini (1998) Lower intracellular hydrogen peroxide levels in cells overexpressing CuZn-superoxide dismutase. 95(14), 7872-7875.
Luisa Sandalio, Eduardo López-Huertas, Pablo Bueno, Luis Del Río (1997) Immunocytochemical Localization of Copper, Zinc Superoxide Disrnutase in Peroxisomes from Wihermelon ( Citrullus vulgaris Schrad.) Cotyledons. 26(3), 187-194.
Kumar Ganesan, Kumeshini Sukalingam, Baojun Xu (2017) Solanum trilobatum L. Ameliorate Thioacetamide-Induced Oxidative Stress and Hepatic Damage in Albino Rats. 6(3), 68.
Qi-Ming Yu, Eun-Ji Lim, Soo-Kyong Choi, Jung-Sook Seo (2014) Antioxidant effect of grapevine leaf extract on the oxidative stress induced by a high-fat diet in rats. 23(3), 849-857.
O Oseni, S Olagboye, O Adams, P Akintayo (2019) Synthesis, Partial Characterization of Chitosan-Iron Complex and its Effects on Alloxan Induced Diabetic Mellitus in Wistar Albino Rats International. 10(4), 20726-20736.
Published
2021-10-27
Issue
Section
License
Copyright (c) 2021 Authors and Global Journals Private Limited
This work is licensed under a Creative Commons Attribution 4.0 International License.