Abstract

Organophosphate compounds have been a common source of mortality in recent times. A typical example is dichlorvos [2, 2-Dichlorovinyldimethylphosphate (DDVP)]; an important agricultural pesticide. This study sought to investigate the phytochemical screening, in-vitro antioxidant property of the leaf solvents extracts and ameliorating effects of Senna siameain DDVP-induced brain oxidative stress in Wistar rats. The aqueous, methanol and ethanol extracts of the leaves were obtained and analyzed for their in-vitro antioxidant parameters. Thirty-two healthy Wistar albino rats were grouped into eight of 4rats each weighing between 140-150g. The animals were orally administered with 6.6mg/kg body weight of DDVP except groups1 and 2 followed by treatments with the three solvents extracts respectively that lasted for four weeks.

How to Cite
OLAIYA PETER, OSENI, OLATUNDE ABASS, OKOH, OLAYINKA SUNDAY, Oni,. The Impact of Senna Siamea (Lam) leaves extracts on 2, 2-Dichlorovinyldimethyl Phosphate Induced Brain Oxidative Stress in Wistar Albino Rats. Global Journal of Medical Research, [S.l.], oct. 2021. ISSN 2249-4618. Available at: <https://medicalresearchjournal.org/index.php/GJMR/article/view/2552>. Date accessed: 06 july 2022.


Organize Conference

We organize seminars /symposium /conferences/workshop/webinar worldwide on innovative topics and fields of Computer Science and research. We also collaborate, partner or sponsor with a view to provide our professional guidance and expertise to conduct in standard way.

Read More

Research Membership

Global Journals Inc., as described in our Corporate Statement, is an educational, research, research publishing, and professional membership organization. Elevation to the ranks of Fellow of the Association of the Research Society in Computer and Member of the Association of the Research Society in Computer is open.

Read More