Analytical Method for Estimation of Losartan by using UV a Spectrophotometer

Authors

  • Dr. Safila Naveed

  • Dr. Safila Naveed

Keywords:

assay, losartan, UV pectrophotometer

Abstract

A simple, accurate, and economical least time consuming method for losartan method has been developed using Uv spectrophotometer.The assay is based on the UV absorbance maxima at about wavelength of 234nm using distilled water as solvent. Six sample of drug were dissolved in distilled water to produce solutions containing different brands of losartan. The absorbance of these six drugs were measured at 234 nm against the solvent blank and the assay were calculated by using the absorbance of active.This method can be used for the quality control QC quantitation and analysis of losartan in active and tablet formulations.

How to Cite

Analytical Method for Estimation of Losartan by using UV a Spectrophotometer. (2014). Global Journal of Medical Research, 14(B4), 15-17. https://medicalresearchjournal.org/index.php/GJMR/article/view/100361

References

Giuseppe Carlucci, Giancarlo Palumbo, Pietro Mazzeo, Maria Giovanna Quaglia (2000) Simultaneous determination of losartan and hydrochlorothiazide in tablets by high-performance liquid chromatography. 23(1), 185-189.

Maria Del Rosario, B Contreras, Y Clavijo, S Torres, D Delgado, Y (2009) Determination of Losartan, Telmisartan, and Valsartan by Direct Injection of Human Urine into a Column-Switching Liquid Chromatographic System with Fluorescence Detection. 50, 194-199.

R Williams, M Alasandro, V Fasone, R Boucher, J Edwards (1996) Comparison of liquid chromat-ography, capillary electrophoresis and super-critical fluid chromatography in the determination of Losartan Potassium drug substance in Cozaar tablets. 14, 1539-1546.

H Habib, S Weshahy, S Toubar, Mma El-Alamin (2008) Cathodic Stripping Voltammetric 100 100.

Olga Lastra, Igor Lemus, Hugo Sánchez, Renato Pérez (2003) Development and validation of an UV derivative spectrophotometric determination of Losartan potassium in tablets. 33(2), 175-180.

A Ensafi, R Hajian (2008) Determination of losartan and triamterene in pharmaceutical compounds and urine using cathodic adsorptive stripping voltammetry. 24, 1449-1454.

Analytical Method for Estimation of Losartan by using UV a Spectrophotometer

Published

2014-09-04

How to Cite

Analytical Method for Estimation of Losartan by using UV a Spectrophotometer. (2014). Global Journal of Medical Research, 14(B4), 15-17. https://medicalresearchjournal.org/index.php/GJMR/article/view/100361