Abstract

Pre-eclampsia is defined by the new onset of elevated blood pressure and proteinuria after 20 weeks of gestation.According to current studies dyslipidemia, particularly the rise in serum triglycerides is a contributing factor in pre-eclampsia. There is a positive correlation between serum triglycerides and systolic blood pressure in pre-eclampsia cases .Urinary protein- creatinine ratio has been used to evaluate proteinuria in pre-eclampsia, this parameter is sensitive and predictive as well.The presence of proteinuria is seen as a possible indication of many complications in pregnancy, from urinary tract infection to chronic renal disease and it remains central to the diagnosis of pre-eclampsia in a hypertensive pregnancy. It has both diagnostic and prognostic implications . Extensive changes occur in the renal system in pre-eclampsia. As a part of the end organ pathology pre-eclamptic glomeruli undergo structural changes with pronounced endothelial vacuolization and hypertrophy of the cytoplasmic organelles, first defined as glomerular endotheliosis. A case control comparative study was done with preeclampsia and normal pregnant women .both for out door patient and indoor patients of Basaveshwara Medical College Hospital