Pyridoxine Toxicity in Pediatric Patient with ESRD on Peritoneal Dialysis. Case Report
Keywords:
pyridoxine, children, toxicity
Abstract
Pyridoxine induced toxicity was first described in 1984 in 58 years old female patient who used megadose as prescribed by her physician to treat carpal tunnel syndrome. Later on, couple of case report also reported different forms of neurosensory toxicity in adult patients on high doses and/or long-term therapy of pyridoxine. We present the first case of pyridoxine toxicity in pediatric patient received therapeutic dose of pyridoxine of 1 mg/kg/day once daily who presented with low blood pressure, headache and hypersomnia.
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References
Carlos-Alberto Calderon-Ospina, Mauricio Nava-Mesa, Ana Paez-Hurtado (2020) Update on Safety Profiles of Vitamins B1, B6, and B12: A Narrative Review. Volume 16, 1275-1288.
J-P Camdessanche, G Jousserand, K Ferraud, C Vial, P Petiot, J Honnorat, J-C Antoine (2009) The pattern and diagnostic criteria of sensory neuronopathy: a case-control study. 132(7), 1723-1733.
Catherine Clase, Vincent Ki, Rachel Holden (2013) Water‐Soluble Vitamins in People with Low Glomerular Filtration Rate or On Dialysis: A Review. 26(5), 546-567.
Melissa Corken, Judi Porter (2011) Is vitamin B6 deficiency an under-recognised risk in patients receiving haemodialysis? A systematic review: 2000-2010. 16(7), no-no.
K Dalton, M Dalton (1987) Characteristics of pyridoxine overdose neuropathy syndrome. 76(1), 8-11.
Felix Hadtstein, Misha Vrolijk (2021) Vitamin B-6-Induced Neuropathy: Exploring the Mechanisms of Pyridoxine Toxicity. 12(5), 1911-1929.
Lyndsay Harshman, Kathy Lee-Son, Jennifer Jetton (2018) Vitamin and trace element deficiencies in the pediatric dialysis patient. 33(7), 1133-1143.
J Heinz (2008) Washout of water-soluble vitamins and of homocysteine during haemodialysis: Effect of high-flux and low-flux dialyser membranes. 384-389.
Triona Joyce, Frances Brown, Shazia Adalat, Christopher Reid, Manish Sinha (2018) Vitamin B6 blood concentrations in paediatric dialysis patients. 33(11), 2161-2165.
J Kopple (1981) Daily requirement for pyridoxine supplements in chronic renal failure. 19(5), 694-704.
George Kosmadakis, Enrique Da Costa Correia, Odette Carceles, Frederic Somda, Didier Aguilera (2014) Vitamins in dialysis: who, when and how much?. 36(4), 638-650.
M Kriley, B Warady (1991) Vitamin status of pediatric patients receiving long-term peritoneal dialysis. 53(6), 1476-1479.
Georg Krinke, Dennis Naylor, Vladimir Skorpil (1981) Pyridoxine Megavitaminosis. 44(2), 117-129.
Kongkiat Kulkantrakorn (2014) Pyridoxine-induced sensory ataxic neuronopathy and neuropathy: revisited. 35(11), 1827-1830.
Mydlík, Derzsiová, Šváč, Dlhopolček, Žemberová (1998) Peritoneal Clearance and Peritoneal Transfer of Oxalic Acid, Vitamin C, and Vitamin B6 During Continuous Ambulatory Peritoneal Dialysis. 22(9), 784-788.
D Rao, B Jortner, R Sills (2014) Animal Models of Peripheral Neuropathy Due to Environmental Toxicants. 54(3), 315-323.
K Scott, S Zeris, M Kothari (2008) Elevated B6 levels and peripheral neuropathies. 48(5), 219-223.
Patrick Stover, Martha Field (2015) Vitamin B-6. 6(1), 132-133.
Martino Di Salvo, Roberto Contestabile, Martin Safo (2011) Vitamin B6 salvage enzymes: Mechanism, structure and regulation. 1814(11), 1597-1608.
Misha Vrolijk, Antoon Opperhuizen, Eugène Jansen, Geja Hageman, Aalt Bast, Guido Haenen (2017) The vitamin B6 paradox: Supplementation with high concentrations of pyridoxine leads to decreased vitamin B6 function. 44, 206-212.
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2023-02-22
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