Unilateral Idiopathic Neuroretinitis Following Pfizer-BioNTech COVID-19 Vaccine; A Case Report
Keywords:
neuroretinitis, COVID-19, SARS-CoV-2, Pfizer, New Zealand
Abstract
This case report describes a temporal relationship of unilateral neuroretinitis following the second Pfizer-BioNTech COVID-19 (Pfizer) vaccine. A 16-year-old male of mixed ethnicity presented with gradual loss of vision and pain on eye movement in his left eye 12 days after his second Pfizer vaccine. His visual acuity in the left eye was count fingers at half a meter. There was optic nerve head swelling, macular exudates in a star-shaped pattern with peripapillary and foveal subretinal fluid consistent with left neuroretinitis. His serological and radiologic investigations were negative for any alternative aetiology. He was commenced on doxycycline, rifampicin and oral prednisone on a tapering dose. 4 months after presentation his left eye vision improved to 6/24-2; limited by loss to the outer retinal layers over the fovea. The close proximity of the second Pfizer vaccine dose poses a temporal association with plausible causation.
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References
Manatu Hauora, Ministry Health (2022) COVID-19 vaccines.
F Polack, S Thomas, N Kitchin, J Absalon, A Gurtman, S Lockhart (2020) Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. 383, 2603-2615.
Taher Eleiwa, Eric Gaier, Abid Haseeb, Reem Elsheikh, Ahmed Sallam, Abdelrahman Elhusseiny (2021) Adverse Ocular Events following COVID-19 Vaccination. 70(10-12), 1005-1009.
Ilaria Testi, Camilo Brandão-De-Resende, Rupesh Agrawal, Carlos Pavesio (2022) Ocular inflammatory events following COVID-19 vaccination: a multinational case series. 12(4).
Rim Kahloun, Imen Khairallah-Ksiaa, Nesrine Abroug, Anis Mahmoud, Salim Ben Yahia, Sonia Zaouali, Bechir Jelliti, Moncef Khairallah (2015) Final Diagnosis in Patients Referred with a Diagnosis of Neuroretinitis. 39(6), 266-270.
Nicky Holdeman, L Ma, R Tang (2017) Cat Scratch Neuroretinitis. 4(2).
Dean Wingerchuk, Brenda Banwell, Jeffrey Bennett, Philippe Cabre, William Carroll, Tanuja Chitnis, Jérôme De Seze, Kazuo Fujihara, Benjamin Greenberg, Anu Jacob, Sven Jarius, Marco Lana-Peixoto, Michael Levy, Jack Simon, Silvia Tenembaum, Anthony Traboulsee, Patrick Waters, Kay Wellik, Brian Weinshenker (2015) International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. 85(2), 177-189.
Chaeyeon Lee, Kyung-Ah Park, Don-Il Ham, Minjung Seong, Hyung-Jin Kim, Ga-In Lee, Sei Oh (2022) Neuroretinitis after the second injection of a SARS-CoV-2-vaccine: A case report. 27, 101592.
Y Cheng, C Margo (2022) Ocular adverse events following vaccination: overview and update. 67(2), 293-306.
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2023-03-27
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