Axillary Nodal Metastases - Prediction by Ultrasound and Digital Mammogram Features of Primary Breast Malignancy

Authors

  • Dr. Sana Shaikh

  • Dr. Kashaf Anwar Arain

  • Aiman Rahim

Keywords:

breast cancer, axillary lymph nodes, metastases, axillary lymph nodes metastases

Abstract

Objective: We have evaluated the value of using the ultrasound and mammographic features of primary breast malignancy to predict axillary lymph node metastasis in patients with known biopsy proven breast cancer. We also determined the impact of demographic factors and various histopathological features of breast cancer on axillary lymph nodes metastasis. Methods: This descriptive retrospective study was an institutional review board-approved study with a waiver of informed consent. Imaging features from 354 patients with digital mammogram and preliminary sonography and histopathological features of invasive breast carcinomas, between March 2021 and August 2022were compared with axillary lymph node status for the presence of metastases. We did univariate and multivariate logistic regression analysis for this purpose.

How to Cite

Axillary Nodal Metastases - Prediction by Ultrasound and Digital Mammogram Features of Primary Breast Malignancy. (2023). Global Journal of Medical Research, 23(D1), 15-27. https://medicalresearchjournal.org/index.php/GJMR/article/view/102344

References

Y Luo, C Zhao, Y Gao, M Xiao, W Li, J Zhang, L Ma, J Qin, Y Jiang, Q Zhu (2020) Predicting Axillary Lymph Node Status With a Nomogram Based on Breast Lesion Ultrasound Features: Performance in N1 Breast Cancer Patients. 10, 581321.

J Yang, T Wang, L Yang, Et Al (2019) Preoperative prediction of axillary lymph node metastases in breast cancer using mammography-based radiomics method. 4429.

Y Bhurgri (2004) Karachi Cancer Registry Dataimplications for the National Cancer Control Program of Pakistan. 5, 77-82.

A Khan, I Masroor, K Khandwala (2020) Utility of Ultrasound and Mammography in Detection of Negative Axillary Nodal Metastasis in Breast Cancer.

Qiang Guo, Zhiwu Dong, Lei Zhang, Chunping Ning, Ziyao Li, Dongmo Wang, Chong Liu, Ming Zhao, Jiawei Tian (2018) Ultrasound Features of Breast Cancer for Predicting Axillary Lymph Node Metastasis. 37(6), 1354-1353.

Jia‐wei Li, Yu‐yang Tong, Yi‐zhou Jiang, Xu‐juan Shui, Zhao‐ting Shi, Cai Chang (2019) Clinicopathologic and Ultrasound Variables Associated With a Heavy Axillary Nodal Tumor Burden in Invasive Breast Carcinoma. 38(7), 1747-1755.

Jung Chang, Jessica Leung, Linda Moy, Su Ha, Woo Moon (2020) Axillary Nodal Evaluation in Breast Cancer: State of the Art. 295(3), 500-515.

W Kim, H Kim, S Lee, S Cho, K Shin, S Lee, J Lim, W Lee (1092) Preoperative axillary nodal staging with ultrasound and magnetic resonance imaging: predictive values of quantitative and semantic features. 91, 20180507.

Matthew Assing, Bhavika Patel, Neel Karamsadkar, Jared Weinfurtner, Omar Usmani, John Kiluk, Jennifer Drukteinis (2017) A comparison of the diagnostic accuracy of magnetic resonance imaging to axillary ultrasound in the detection of axillary nodal metastases in newly diagnosed breast cancer. 23(6), 647-655.

Akissue De, Camargo Teixeira, P Chala, L Shimizu, C Filassi, J Maesaka, J De Barros, N (2017) Axillary Lymph Node Sonographic Features and Breast Tumor Characteristics as Predictors of Malignancy: A Nomogram to Predict Risk. 43(9), 1837-1845.

Jian Zhang, Xiao Li, Rong Huang, Wei-Liang Feng, Ya-Nan Kong, Feng Xu, Lin Zhao, Qing-Kun Song, Jing Li, Bao-Ning Zhang, Jin-Hu Fan, You-Lin Qiao, Xiao-Ming Xie, Shan Zheng, Jian-Jun He, Ke Wang (2017) A nomogram to predict the probability of axillary lymph node metastasis in female patients with breast cancer in China: A nationwide, multicenter, 10-year epidemiological study. 8(21), 35311-35325.

Si-Qi Qiu, Huan-Cheng Zeng, Fan Zhang, Cong Chen, Wen-He Huang, Rick Pleijhuis, Jun-Dong Wu, Gooitzen Van Dam, Guo-Jun Zhang (2016) A nomogram to predict the probability of axillary lymph node metastasis in early breast cancer patients with positive axillary ultrasound. 6(1), 21196.

Yu‐yang Tong, Pei‐xuan Sun, Jin Zhou, Zhao‐ting Shi, Cai Chang, Jia‐wei Li (2019) The Association Between Ultrasound Features and Biological Properties of Invasive Breast Carcinoma Is Modified by Age, Tumor Size, and the Preoperative Axilla Status. 39(6), 1125-1134.

(2016) Fig. 1. American College of Radiology breast density scale: a - ACR A; b - ACR B; c - ACR C; d - ACR D. ACR (American College of Radiology) - American College of Radiology..

(2018) Fig. 1. American College of Radiology breast density scale: a - ACR A; b - ACR B; c - ACR C; d - ACR D. ACR (American College of Radiology) - American College of Radiology..

V Upadhyaya, G Lim, Eyk Chan, Smc Fook-Chong, Lch Leong (2019) Evaluating the preoperative breast cancer characteristics affecting the accuracy of axillary ultrasound staging. 26(2), 162-167.

Haoyu Wang, Weiwei Zhan, Weiguo Chen, Yafen Li, Xiaosong Chen, Kunwei Shen (2019) Sonography with vertical orientation feature predicts worse disease outcome in triple negative breast cancer. 49, 33-40.

Sana Shaikh, Afshan Rasheed (2021) Predicting Molecular Subtypes of Breast Cancer with Mammography and Ultrasound Findings: Introduction of Sono-Mammometry Score. 2021, 1-12.

Zhuangsheng Liu, Ruqiong Li, Keming Liang, Junhao Chen, Xiangmeng Chen, Xiaoping Li, Ronggang Li, Xin Zhang, Lilei Yi, Wansheng Long (2020) Value of digital mammography in predicting lymphovascular invasion of breast cancer. 20(1), 274.

Yong Eom, Eun Kim, Byung Chae, Byung Song, Sang Jung (2015) The distance between breast cancer and the skin is associated with axillary nodal metastasis. 111(7), 824-828.

J Wu, H Tseng, L Yang, H Wu, S Kuo, S Chen, D Chen (2014) Prediction of axillary lymph node metastases in breast cancer patients based on pathologic information of the primary tumor. 20, 577-581.

Jonathan Cools‐lartigue, Sarkis Meterissian (2012) Accuracy of Axillary Ultrasound in the Diagnosis of Nodal Metastasis in Invasive Breast Cancer: A Review. 36(1), 46-54.

Axillary Nodal Metastases - Prediction by Ultrasound and Digital Mammogram Features of Primary Breast Malignancy

Published

2023-06-07

How to Cite

Axillary Nodal Metastases - Prediction by Ultrasound and Digital Mammogram Features of Primary Breast Malignancy. (2023). Global Journal of Medical Research, 23(D1), 15-27. https://medicalresearchjournal.org/index.php/GJMR/article/view/102344