Musculoskeletal Complications Associated with Vitamin D Deficiency and Review of Current Interventions
Keywords:
vitamin D, musculoskeletal, osteoporosis, rickets, bone fracture, bone density
Abstract
Background: Hypovitaminosis D is commonly prevalent in older population world over leading to increased levels of bone resorption, reduced bone mass, often resulting inosteoporosis and increased chances of falls and fractures. In children, vitamin D deficiency is known to cause rickets due to hypomineralization of bone.
Downloads
How to Cite
References
J Maclaughlin, M Holick (1985) Aging decreases the capacity of human skin to produce vitamin D3.. 76(4), 1536-1538.
M Holick, L Matsuoka, J Wortsman (1989) Age, vitamin D, and solar ultraviolet. 2, 1104-1105.
M Holick (1994) Mccollum award lecture, 1994: Vitamin D -new horizons for the 21 st Century. 60, 619-630.
(1924) Scientific Opinion on the substantiation of a health claim related to vitamin D and contribution to normal bone and tooth development pursuant to Article 14 of Regulation (EC) No 1924/2006. 12(2).
P Lips (2001) Vitamin D Deficiency and Secondary Hyperparathyroidism in the Elderly: Consequences for Bone Loss and Fractures and Therapeutic Implications. 22(4), 477-501.
M Urbanska, P Pludowski, E Suchowierska (2021) Vitamin D deficiency in older patients -Problems of sarcopenia, drug interactions, management in deficiency. 13(4), 1247-1286.
Nicole Wright, Anne Looker, Kenneth Saag, Jeffrey Curtis, Elizabeth Delzell, Susan Randall, Bess Dawson-Hughes (2014) The Recent Prevalence of Osteoporosis and Low Bone Mass in the United States Based on Bone Mineral Density at the Femoral Neck or Lumbar Spine. 29(11), 2520-2526.
(2004) Executive Summary: Mental Health: A Report of the Surgeon General.
Russel Burge, Bess Dawson-Hughes, Daniel Solomon, John Wong, Alison King, Anna Tosteson (2007) Incidence and Economic Burden of Osteoporosis-Related Fractures in the United States, 2005-2025. 22(3), 465-475.
L Raisz (2005) Pathogenesis of osteoporosis: concepts, conflicts, and prospects. 115(12), 3318-3325.
F Cosmon, S De Beur, M Leboff, F Lewiecki, B Tanner, S Randall (2014) Clinician's guide to prevention and treatment of osteoporosis. 25(10), 2045-2047.
M Jeremiah, B Unwin, M Greenawald, E Vincent (2015) Diagnosis and Management of osteoporosis. 92(4), 261-268.
(2010) Management of osteoporosis in postmenopausal women: 2010 Position Statement of The North American Menopause Society. 17(1), 25-54.
D Hunter, P Sambrook (2000) Bone Loss: Epidemiology of bone loss. 2(6), 441-445.
Zh Belaya (2015) WEEK OF OSTEOPOROSIS AND OTHER METABOLIC BONE DISEASES AT ENDOCRINOLOGY RESEARCH CENTER RUSSIAN MINISTRY OF HEALTH. 19(1), 3-3.
Lenore Buckley, Gordon Guyatt, Howard Fink, Michael Cannon, Jennifer Grossman, Karen Hansen, Mary Humphrey, Nancy Lane, Marina Magrey, Marc Miller, Lake Morrison, Madhumathi Rao, Angela Byun Robinson, Sumona Saha, Susan Wolver, Raveendhara Bannuru, Elizaveta Vaysbrot, Mikala Osani, Marat Turgunbaev, Amy Miller, Timothy Mcalindon (2017) 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid‐Induced Osteoporosis. 69(8), 1095-1110.
Ral Sutton, L Dian, P Guy (2011) Osteoporosis in men: an under recognised and undertreated problem. 53(10), 535-540.
C Tennenbaum, J Clark, K Schwartzman, S Wallenstein, R Lapinski, D Meier (2002) Yield of laboratory testing to identify secondary contributors to osteoporosis in otherwise healthy women. 87(10), 4431-4437.
K Tu, J Lie, Hyun (2018) Osteoporosis: A review of treatment options. 43(2), 92-104.
Madhusmita Misra, Danièle Pacaud, Anna Petryk, Paulo Collett-Solberg, Michael Kappy (2008) Vitamin D Deficiency in Children and Its Management: Review of Current Knowledge and Recommendations. 122(2), 398-417.
P Lips, K Cashman, C Lamberg -Allardt, H Bischoff -Ferrari, B Obermayer -Pietsch, M Bianchi (2019) Current vitamin D status in European and Middle East countries and strategies to prevent vitamin D deficiency; a position statement of the European Calcifed Tissue Society. 180(4), 23-54.
Richard Lewis, Emma Laing (2015) Conflicting reports on vitamin D supplementation: Evidence from randomized controlled trials. 410, 11-18.
Rebecca Moon, Justin Davies, Cyrus Cooper, Nicholas Harvey (2020) Vitamin D, and Maternal and Child Health. 106(1), 30-46.
Sarah Taylor (2020) Vitamin D in Toddlers, Preschool Children, and Adolescents. 76(Suppl. 2), 30-41.
Donald Bailey, Alan Martin, Heather Mckay, Susan Whiting, Robert Mirwald (2000) Calcium Accretion in Girls and Boys During Puberty: A Longitudinal Analysis. 15(11), 2245-2250.
Steven Boonen, Paul Lips, Roger Bouillon, Heike Bischoff-Ferrari, Dirk Vanderschueren, Patrick Haentjens (2007) Need for Additional Calcium to Reduce the Risk of Hip Fracture with Vitamin D Supplementation: Evidence from a Comparative Metaanalysis of Randomized Controlled Trials. 92(4), 1415-1423.
M Bolland, G Avenell, G Gamble (2010) Effect of calcium supplements on risk if myocardial infarction and cardiovascular events: meta -analysis. 341, 3691.
S Meryl, M Leboff, H Sharon, M Chou, E Murata, C Donlon (2020) Effects of supplemental vitamin D on bone health outcomes in women and men in the vitamin D and Omeg A-3 trial (VITAL). 35(5), 883-893.
L Burt, E Billington, M Rose, D Raymond, D Hanley, S Boyd (2019) Effect of high dose vitamin D supplementation on volumetric bone density and bone strength: A randomized controlled trial. 322(8), 736-745.
Terry Aspray, Thomas Chadwick, Roger Francis, Elaine Mccoll, Elaine Stamp, Ann Prentice, Alexander Von Wilamowitz-Moellendorff, Inez Schoenmakers (2019) Randomized controlled trial of vitamin D supplementation in older people to optimize bone health. 109(1), 207-217.
K Sanders, A Stuart, E Williamson, J Simpson, M Kotowicz, D Young (2010) Annual high -dose oral vitamin D and falls and fractures in older women: A randomized control trial. 303(18), 1815-1822.
H Smith, F Anderson, H Raphael, P Maslin, S Crozier, C Cooper (2007) Effect of annual intramuscular vitamin D on fracture risk in elderly men and women a population-based, randomized, double-blind, placebo-controlled trial. 46(12), 1852-1857.
Pang Yao, Derrick Bennett, Marion Mafham, Xu Lin, Zhengming Chen, Jane Armitage, Robert Clarke (2019) Vitamin D and Calcium for the Prevention of Fracture. 2(12), e1917789.
T Winzenberg, S Powell, K Shaw, G Jones (2011) Effects of vitamin D supplementation on bone density in healthy children: systematic review and meta-analysis. 342(jan25 1), c7254-c7254.
Tania Winzenberg, Sandi Powell, Kelly Shaw, Graeme Jones (2010) Vitamin D supplementation for improving bone mineral density in children. 10, 6944.
A Khadilkar, M Sayyad, N Sanwalka, D Bhandari, S Naik, V Khadilkar (2010) Vitamin D supplementation and bone mass accrual in underprivileged adolescent Indian girls. 19(4), 465-472.
Dimitri Ceroni, Rebecca Anderson De La Llana, Xavier Martin, Léopold Lamah, Geraldo De Coulon, Katia Turcot, Victor Dubois-Ferrière (2012) Prevalence of vitamin D insufficiency in Swiss teenagers with appendicular fractures: A prospective study of 100 cases. 6(6), 497-503.
Leticia Ryan, Stephen Teach, Steven Singer, Rachel Wood, Robert Freishtat, Joseph Wright, Robert Mccarter, Laura Tosi, James Chamberlain (2012) Bone Mineral Density and Vitamin D Status Among African American Children With Forearm Fractures. 130(3), e553-e560.
L Anderson, W Heong, Y Chen, K Thorpe, K Adeli, A Howard, E Sochett, C Birken, P Parkin, J Maguire (2017) 10: Vitamin D and Fracture Risk in Early Childhood: A Case-Control Study. 20(5), e34-e34.
Sabah Servaes, Lisa States, Joanne Wood, Samantha Schilling, Cindy Christian (2020) Rachitic change and vitamin D status in young children with fractures. 49(1), 85-91.
Nicklas Brustad, Bo Chawes, Jonathan Thorsen, Martin Krakauer, Jessica Lasky-Su, Scott Weiss, Jakob Stokholm, Klaus Bønnelykke, Hans Bisgaard (2022) High-dose vitamin D supplementation in pregnancy and 25(OH)D sufficiency in childhood reduce the risk of fractures and improve bone mineralization in childhood: Follow-up of a randomized clinical trial. 43, 101254.
Published
2023-06-12
Issue
Section
License
Copyright (c) 2023 Authors and Global Journals Private Limited
This work is licensed under a Creative Commons Attribution 4.0 International License.