Five Plants with Promising Antimicrobial Peptides
Keywords:
antimicrobial peptides, plant extract, antibiotic resistance, gram-positive, gram-negative bacteria
Abstract
Antimicrobial peptides (AMPs) are bioactive molecules known for their strong antimicrobial properties against a variety of microorganisms. The increasing prevalence of antibiotic-resistant infections, coupled with a scarcity of newly developed antibiotics, has intensified the search for novel sources of AMPs. Plant-derived AMPs present several benefits compared to conventional antibiotics. Consequently, this research focused on screening various plant species to identify new antimicrobial peptides. Water-soluble proteins were extracted from the dried plant materials using an aqueous extraction buffer. The resulting extracts were evaluated for antibacterial activity, with the minimum inhibitory concentration (MIC) being determined, followed by separation through thin layer chromatography and subsequent agar overlay bioautography. Protein extracts from five different plants exhibited antibacterial properties against both Gram-positive and Gram-negative bacteria, with inhibition zones measuring between 11 and 22 mm.
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2026-01-09
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