A Randomised Controlled Study of Intramuscular Camylofin Dihydrochloride vs Intravenous Hyoscine Butylbromide in Augmentation of Labour

Abstract

Aims and objectives-to study and compare the effectiveness of injection Camylofin and injection Hyoscine in accelerating active phase of the 1st stage of labour in uncomplicated pregnancies. Second was to study the effects of the two drugs on 2nd and 3rd stage of labour and to study the adverse drug reactions on the mother and fetus. Method- This was randomized controlled prospective study.150 Primigravida in the age group 18 to 30 years with gestational age 37 to 40 weeks were included. The cases were divided into 3 groups Group I consisted 50 women which was Control Group. Group II consisted of 50 women who were given injection Camylofin intramuscular. Group III consisted of 50 women who were given injection Hyoscine intravenous. Result-There was significant reduction in duration of active phase of labour and improvement in the rate of cervical dilatation with Camylofin compared to Hyoscine butylbromide. There were no maternal, fetal side effects associated to these drugs.