Bacteriological Profile and Antibiotic Susceptibility Pattern of Blood Culture Isolates from Patients Visiting Janamaitri Hospital, Balaju, Kathmandu, Nepal
Keywords:
blood stream infections, multi-drug resistant, salmonella paratyphi A, janamaitri hospital
Abstract
Bacterial blood stream infections can lead to life threatening sepsis that requires rapid antimicrobial treatment otherwise may lead to morbidity and mortality of patients. Blood culture is gold standard technique which provides essential information for the diagnosis and appropriate medication to save life of affected patients. Present study was conducted to determine the bacteriological profile of blood stream infections and their antibiotic susceptibility pattern in patients visiting Janamaitri Hospital, Balaju, Kathmandu, Nepal. A total of 838 blood samples were collected from the clinically suspected cases of bacteremia and septicaemia. Isolates were identified by standard biochemical tests, and antibiotic susceptibility test was performed by using CLSI guidelines. Positive blood culture was obtained in 61/838 (7.28%) where gram negative accounted for 48/61 (78.69%) in which Salmonella Paratyphi A was leading organisms and gram positive accounted for 13/61(21.31%) in which Staphylococcus aureus was leading organisms.
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References
S Trevino, D Ross (2007) Bacterermia and Sepsis. 995-1009.
T Zenebe, S Kannan, D Yilma, G Beyene (2011) Invasive Bacterial Pathogens and their Antibiotic Susceptibility Patterns in Jimma University Specialized Hospital, Jimma, Southwest Ethiopia. 21(1), 1-8.
J William, Max (1998) Bacteremia, septicemia and endocarditis. 3(11 th), 178-187.
M Cheesbrough (2006) District Laboratory practice in tropical countries. 124-130.
P Murray, K Rosenthal, M Pfaller (2013) Medical Microbiology seventh edition Saunders. 157.
S Garg, Anupurba, Garg (2007) Bacteriological profile and antimicrobial resistance of blood culture isolates from a university hospital. 8(2), 139-143.
Surya Subedi, Mahesh Chaudhary, Bidya Shrestha (2016) High MDR and ESBL Producing Escherichia coli and Klesbiella pneumoniae from Urine, Pus and Sputum Samples. 13(10), 1-10.
J Collee, J Duguid, A Fraser, B Marmion, A Simmons (2006) Laboratory strategies in the diagnosis of infective syndromes. 55-57.
K Gohel, A Jojera, S Soni, S Gang, R Sabnis, M Desai (2014) Bacteriological profile and drug resistance patterns of blood culture isolates in a tertiary care nephrourology teaching institute. 1-5.
J Collee, Mackie (1996) Mackie and McCartney Practical Medical Microbiology, 14th edition. 45(6), 512-513.
(2012) Clinical Laboratory Standard Institute Performance Standards for Antimicrobial Susceptibility Testing; Twenty-second Informational Supplement. 32, 70-71.
A Magiorakos, A Srinivasan, R Carey, Y Carmeli, M Falagas (2012) Multidrug resistance, extensively drug resistance and pandrug-resistance bacteria: An international expert proposal for interim standard definitions for acquired resistance. 18, 268-281.
D Sham, C Thomsberry, D Mayfield, M Jones, J Karlowsky (2001) Multidrug resistant urinary tract isolates of Escherichia coli: Prevalence and patient demographics in United States in 2000. 45(5), 1402-1406.
(2010) An Overview of the Clinical and Laboratory Standards Institute (CLSI) and Its Impact on Antimicrobial Susceptibility Tests. 15-20.
A Magiorakos, A Srinivasan, R Carey, Y Carmeli, M Falagas, C Giske, J Harbarth, G Kahlmeter, B Olsson-Liljequist, D Paterson, L Rice, M Struelens, A Vatopoulos, J Weber, D Monnet (2012) Multidrug-resistant, extensively drug-resistant and pandrugresistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. 18(3), 268-281.
J Burke (1999) Editorial Board. 61(11), 755.
G Larry, L Michael, P Melvin (1997) Update on Detection of Bacteremia and Fungemia. 10(3), 444-465.
S Subedi, J Maharjan, B Shrestha (2016) Antibiotic susceptibility test of Klebsiella pneumoniae and K. oxytoca isolated from different clinical samples and perform random amplified polymorphic DNA among K. pneumoniae. 12(6), 1-11.
Shubana Karki, Ganesh Rai, Rekha Manandhar (2010) Bacteriological Analysis and Antibiotic Sensitivity Pattern of Blood Culture Isolates in Kanti Children Hospital. 30(2), 94-97.
P Bhandari, S Manandhar, B Shrestha, N Dulal (2016) Etiology of bloodstream infection and antibiotic susceptibility pattern of the isolates. 7(2), 71-75.
M Kante, P Uma, John Ms, M Naidu (2014) Bacterial profile of blood stream infections and antibiotic susceptibility pattern of isolates. 3(12), 222-233.
A Magiorakos, A Srinivasan, R Carey, Y Carmeli, M Falagas (2012) Multidrug resistance, extensively drug resistance and pandrug-resistance bacteria: An international expert proposal for interim standard definations for acquired resistance. 18, 268-281.
A Labi, N Obeng-Nkrumah, Addison No, E Donkor (2014) Salmonella blood stream infections in a tertiary care setting in Ghana. 14, 3857.
N Sharma, R Koju, B Karmacharya, M Tamang, R Makaju, N Nepali (2004) Typhoid fever in Dhulikhel hospital, Nepal. 2, 188-192.
Dharm Bhatta, Abhishek Gaur, H Supram (2013) Bacteriological profile of blood stream infections among febrile patients attending a tertiary care centre of Western Nepal. 4(3), 92-98.
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2016-05-10
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