Cardiovascular comorbidities are most frequent comorbidities in COPD and are responsible for many deaths in those patients. The aim of the study was to investigate the prevalence and the risk factors of these comorbidities. In the survey 114COPD patients were included with severe and very severe stage of the disease, FEV1<50%, which were stable. Cardiovascular comorbidity was detected in 92 (80.7%) respondents, 61.9 % with severe and 38.1 % with very severe COPD. Blood sugar (p=0.023*), CRP (p=0.00007**), CAT score (p<0.0006**) and number of exacerbations (p<0.0001) were significantly higher in patients with cardiovascular comorbidity. We can conclude that cardiovascular comorbidities are frequent in COPD patients with severe and very severe stage. They have a great impact in this patients.