Abstract

The most widely recognized neuropathic syndrome found in individuals with diabetes is diabetic peripheral neuropathy. Diabetes is the commonest reason for neuropathy around the world, creating an extensive range of disorders including diverse forms of nerves and pathological mechanisms such as ischemic, metabolic, compressive and immunologic.12 There are different forms of diabetic neuropathies (diffuse or focal) which present with various clinical sign and influencing distinctive parts of the nervous system. The common forms of neuropathies are autonomic neuropathies and chronic sensorimotor distal symmetric polyneuropathy (DPN). Diagnosis of DPN is reached by excluding other disorder that exhibits the same signs.3 Approximately, 8% of general population suffer from long standing pain are caused by the neuropathic pain.4 Around 50% of chronic diabetics#x2019; individuals (more than 25 years) will develop neuropathy which affect their daily living.5 Hyperglycaemia is the chief reason of advancement of all neuropathies, counting PDN. The Diabetes Control and Complications Trial (DCCT) demonstrated that good glycaemic control will lessen the occurrence of neuropathy up to 60%.6