Prognostic Factors Affecting Management of Liposarcoma
Keywords:
liposarcoma, prognostic factors, management
Abstract
Soft tissue sarcomas account for 1% of all neoplasms, with the second commonest being liposarcomas. Liposarcomas in the popliteal fossa often grows to a large size, as neither the patient nor the clinician will initially be able to palpate the tumour due to its depth in the tissues and the fact that the tumour is often low grade. Its size often does not facilitate the ability to resect the mass with wide margins. The following article discusses prognostic factors for liposarcomas with regards to histological subtype, anatomical distribution, resection margins and neoadjuvant therapy.
Downloads
- Article PDF
- TEI XML Kaleidoscope (download in zip)* (Beta by AI)
- Lens* NISO JATS XML (Beta by AI)
- HTML Kaleidoscope* (Beta by AI)
- DBK XML Kaleidoscope (download in zip)* (Beta by AI)
- LaTeX pdf Kaleidoscope* (Beta by AI)
- EPUB Kaleidoscope* (Beta by AI)
- MD Kaleidoscope* (Beta by AI)
- FO Kaleidoscope* (Beta by AI)
- BIB Kaleidoscope* (Beta by AI)
- LaTeX Kaleidoscope* (Beta by AI)
How to Cite
References
C Fletcher, K Umi, F Mertens (2002) World Health Organisation classification of tumours pathology and genetics of tumours of soft tissue and bone. 35-46.
A Jemal, R Siegel, E Ward, Y Hao, J Xu, T Murray, M Thun (2008) Cancer Statistics, 2008. 58(2), 71-96.
Hyo Kim, Jeeyun Lee, Seong Yi, Hyun Jun, Yoon-La Choi, Geung Ahn, Sung Seo, Do Lim, Yong Ahn, Joon Park, Sung Kim (2009) Liposarcoma: exploration of clinical prognostic factors for risk based stratification of therapy. 9(1), 205.
A Leow, A Halim, Z Win (2005) Reconstructive treatment following resection of high-grade soft-tissue sarcomas of the lower limb. 13(1), 58-63.
N Gilbert, C Cannon, P Lin, O Valerae (2009) Soft tissue sarcoma. 17(1), 40-47.
W Mendenhall, D Indelicato, M Scarborough, R Zlotecki, C Gibbs, N Mendenhall (2009) The management of adult soft tissue sarcomas. 32(4), 436-442.
Franklin Sim, Frank Frassica, Deborah Frassica (1994) Soft-Tissue Tumors: Diagnosis, Evaluation, and Management. 2(4), 202-211.
C Chandrasekar, H Wafa, R Grimer, S Cater, R Tillman, A Abudu (2008) The effect of an unplanned excision of a soft-tissue sarcoma on prognosis. 90(2), 203-208.
Jonathan Lewis, Murray Brennan (1996) Soft tissue sarcomas. 33(10), 820-872.
J Peterson, M Kransdorf, L Bancroft, M O'connor (2003) malignant fatty tumors: classification, clinical course, imaging appearance and treatment. 32(9), 493-503.
F Enzinger, S Weiss, Liposarcoma, S Weiss, J Goldblum, F Enzinger, Enzinger, Weiss (1995) s Soft Tissue Tumors. 821-828.
David Linehan, Jonathan Lewis, Denis Leung, Murray Brennan (2000) Influence of Biologic Factors and Anatomic Site in Completely Resected Liposarcoma. 18(8), 1637-1643.
Dempsey Springfield (1993) Liposarcoma. 289, 50???57.
Y Ng, M Tan (2009) Liposarcoma of the extremities: a review of the cases seen and managed in a major tertiary hospital in Singapore. 50(9), 857-861.
D Lucas, A Nascimento, B Sanjay, M Rock (1994) Well-differentiated liposarcoma. The Mayo Clinic experience with 58 cases. 102(5), 677-683.
S Weiss, V Rao (1992) Well-differentiated liposarcoma (atypical lipoma) of deep soft tissue of the extremities, retroperitoneum, and miscellaneous sites. A follow-up study of 92 cases with analysis of the incidence of "dedifferentiation. 16(11), 1051-1058.
S Lietman, W Barsoum, J Goldblum, K Marks, E Mascha, M Sundaram (2007) A 20-Year Retrospective Review of Surgically Treated Liposarcoma at the Cleveland Clinic. 30(3), 227-234.
Andrea Ferrari, Michela Casanova, Filippo Spreafico, Roberto Luksch, Monica Terenziani, Graziella Cefalo, Maura Massimino, Lorenza Gandola, Piera Navarria, Franca Fossati-Bellani (1999) CHILDHOOD LIPOSARCOMA: A Single-Institutional Twenty-Year Experience. 16(5), 415-421.
P Gustafson, A Rydholm, H Willen, B Baldetorp, M Ferno, M Akerman (1993) Liposarcoma: a population based epidemiologic and prognostic study of features of 43 patients, including tumor DNA content. 55, 541-546.
P Reszel, E Soule, M Coventry (1966) Liposarcoma of the extremities and limb girdles. A study of two hundred twenty-two cases. 48(2), 229-244.
Hans-Ulrich Steinau, Adrien Daigeler, Stefan Langer, Lars Steinsträsser, Jörg Hauser, Ole Goertz, Markus Lehnhardt (2010) Limb Salvage in Malignant Tumors. 24(01), 018-033.
Edward Cheng, Dempsey Springfield, Henry Mankin (1995) Frequent incidence of extrapulmonary sites of initial metastasis in patients with liposarcoma. 75(5), 1120-1127.
K Dalal, M Kattan, C Antonescu, M Brennan, S Singer (2006) Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk. 244(3), 381-391.
Gunar Zagars, Mary Goswitz, Alan Pollack (1996) Liposarcoma: Outcome and prognostic factors following conservation surgery and radiation therapy. 36(2), 311-319.
D Mccormick, T Mentzel, A Beham, C Fletcher (1994) Dedifferentiated liposarcoma. Clinicopathologic analysis of 32 cases suggesting a better prognostic subgroup among pleomorphic sarcomas. 18(12), 1213-1223.
Helena Chang, Steven Hajdu, Charles Collin, Murray Brennan (1989) The prognostic value of histologic subtypes in primary extremity liposarcoma. 64(7), 1514-1520.
T Mentzel, C Fletcher (1997) Dedifferentiated myxoid liposarcoma: a clinicopathological study suggesting a closer relationship between myxoid and well‐differentiated liposarcoma. 30(5), 457-463.
J Wu, E Montgomery (2008) Classification and pathology. 88(3), 483-484.
Tamara Smith, Kirk Easley, John Goldblum (1996) Myxoid/Round Cell Liposarcoma of the Extremities. 20(2), 171-180.
David Pearlstone, Peter Pisters, Richard Bold, Barry Feig, Kelly Hunt, Alan Yasko, Shreyaskumar Patel, Alan Pollack, Robert Benjamin, Raphael Pollock (1999) Patterns of recurrence in extremity liposarcoma. 85(1), 85-92.
G Orson, F Sim, H Reiman, W Taylor (1987) Liposarcoma of the musculoskeletal system. 15(6), 1362-1370.
R De Vreeze, D De Jong, P Nederlof, A Ariaens, I Tielen, L Frenken (2010) Added Value of Molecular Biological Analysis in Diagnosis and Clinical Management of Liposarcoma: A 30-Year Single-Institution Experience. 17(3), 686-693.
O Berlin, B Stener, L Angerval, L-G Kindblom, G Markhede, A Oden (1990) Surgery for soft tissue sarcoma in the extremities. A multivariate analysis of the 6-26-year prognosis in 137 patients. 61(6), 475-523.
Matthew Hueman, Katherine Thornton, Joseph Herman, Nita Ahuja (2008) Management of Extremity Soft Tissue Sarcomas. 88(3), 539-557.
A Kaushal, D Citrin (2008) The role of radiation therapy in the management of sarcomas. 88(3), 629-646.
Corinne Sadoski, Herman Suit, Andrew Rosenberg, Henry Mankin, Jimmy Efird (1993) Preoperative radiation, surgical margins, and local control of extremity sarcomas of soft tissues. 52(4), 223-230.
E Baldini, J Goldberg, C Jenner, J Manola, G Demetri, C Fletcher (1999) Long-term outcomes after function-sparing surgery without radiotherapy for soft tissue sarcoma of the extremities and trunk. 17(10), 3252-3259.
Diego Ribuffo, Maria Giuseppina Onesti, Emilia Elia, Vittorio Cucchiara, Maurizio Valeriani, Nicolò Scuderi (1998) CONTROVERSIAL ISSUES IN DIAGNOSIS OF LIPOSARCOMAS OF THE THIGH: A report of 18 cases. 32(3), 323-330.
Fritz Eilber, Frederick Eilber, Jeffery Eckardt, Gerald Rosen, Elyn Riedel, Robert Maki, Murray Brennan, Samuel Singer (2004) The Impact of Chemotherapy on the Survival of Patients With High-grade Primary Extremity Liposarcoma. 240(4), 686-697.
C Knebel, U Lenze, F Pohlig, F Lenze, N Harrasser, C Suren, H Mühlhofer (2017) Prognostic factors and outcome of Liposarcoma patients: a retrospective evaluation over 15 years. 17, 410.
Published
2018-01-24
Issue
Section
License
Copyright (c) 2017 Authors and Global Journals Private Limited

This work is licensed under a Creative Commons Attribution 4.0 International License.