Studies on Majoon Aarad Khurma and its Granules Prepared with Stevia, with Reference to the Standardization and Toxicity Evaluation

Abstract

There is a huge treasure of Compound drugs described in various pharmacopoeias that have developed as a result of painstaking and cumulative efforts of elite scholars of Unani medicine. However, there has always been scope for inclusion of new compound drugs whose safety and efficacy has been proved scientifically. Majoon Aarad Khurma which is widely used as an effective aphrodisiac is prepared with sugar as base. It is contraindicated in diabetic patients who are suffering from sexual dysfunctions. Preparation of medicines which are sugar free should be innovated or designed to meet the demand of the diabetic patients. Therefore the present study is aimed to develop granules of Majoon Aarad Khurma with natural sweetening agent Stevia rebaudiana. Granules are more convenient and comfortable in usage and dispensing. Granules uphold the same principles and maintain the same characteristics as traditional dosage forms, granules are safe, light, efficacious, stable and quality controlled. In present study an important Unani formulation i.e. Majoon Aarad Khurma has been modified into granules using Stevia rebaudiana as a sweetener and the safety and toxicity of the granules of Majoon Aarad Khurma has also been evaluated. Majoon Aarad Khurma and Granules of Majoon Aarad Khurma were prepared and subjected to Physico-Chemical evaluation with reference to the standards mentioned in Physicochemical Standards of Unani formulations by CCRUM.