Tranexamic Acid Coated or Eluted Uterine Balloon and Co- Attached Cervical Shutter in Post Partum Haemorrhage. A New Combatant in the Armamentarium, Not Merely a Balloon but More

Abd El Aal Nasser Kamal

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Abd El Aal Nasser Kamal

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Abstract

Described herein a Tranexamic Acid (TXA) -Coated or Eluted Uterine Balloon for use in an intra uterine location for primary management of postpartum haemorrhage (PPH). It enforces the tamponade effect of currently used non medicated uterine balloons with an additional inbuilt mechanism of local steady release of the antibrinolytic TXA into uterine cavity that has been evidenced to contribute to haemostasis in cases of PPH. The invention ushers a new era of utilizing the uterine balloon surface coat as a delivery vehicle for TXA. This can be achieved via different techniques including and not limited to matrix coating or eluting of nanoparticulate TXA in the outermost layer of the balloon .TXA coated or eluted balloon replenish non medicated balloons with a therapeutic modality of the TXA relatedantifibrinolysis especially in hemorrhages known to be associated with coagulopathy.

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Tranexamic Acid Coated or Eluted Uterine Balloon and Co- Attached Cervical Shutter in Post Partum Haemorrhage. A New Combatant in the Armamentarium, Not Merely a Balloon but More. (2018). Global Journal of Medical Research, 18(E4), 13-22. https://medicalresearchjournal.org/index.php/GJMR/article/view/1644

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