Abstract

Phenolic and Polyphenolic are important compounds from the class of phytomedicine and are widely distributed in the plant kingdom Over the years an increasing amount of interest has been vastly drawn into the plant polyphenolic mainly because these compounds have shown tremendous efficacy in the treatment of oxidative stress-related diseases such as cancer Currently much medical investigations are conducted on plant phenolic for improving their identification and development for better therapeutic efficacy in the fight against different types of cancers We aim to update and provide an extensive overview of the mechanism of action and the role of phenolic compounds in the treatment of tumor The various databases used to conduct the literature survey are Pub Med Central Scopus Research Gate EMBASE Google Scholar Science Direct Sci ELO PLoS Public Library of Science In the first stage it includes different types of cancers and their biomarkers In second stage different phenolic compounds in plants and their role in the cancer treatment Finally to find out the mechanism of action and clinical status of phenolic compounds against different biomarkers and the mechanism of action of phenolic and polyphenolic compounds against cancer and its biomarkers with their antioxidant activity