In Vitro Antioxidant, Anti-Inflammatory And Anti-Microbial Activity of Carica Papaya Seeds

Authors

  • Kanthesh M Basalingappa

  • Pooja G. Singh

  • Madhu S. B

  • Shailasree Sekhar

  • Gopenath TS

  • Dr. Sushma BV

Keywords:

carica papaya L, seed extracts, phytochemical analysis, antioxidant, lipoxygenase inhibition, antimicrobial activity

Abstract

Papaya seeds are reported to have higher therapeutic potential in comparison to the fruits in which they reside Thus the present in-vitro study aimed to evaluate and compare the anti-oxidant anti-inflammatory and anti-microbial effect of seed extracts on Carica papaya L Caricaceae The bioactive form the seeds were sequentially fractionated with hexane chloroform diethyl ether and methanol in the increasing order of polarity Total phenolic and flavonoid contents were estimated These extracts were assessed for an antioxidant property by 1 1-diphenyl-2-picryl-hydroxyl DPPH method and reducing power assay was carried out using the FeCl3 method Inhibition of 15-lipoxygenase LOX by these extracts at 5 - 25 g to asses anti-inflammatory capacity was studied

How to Cite

Kanthesh M Basalingappa, Pooja G. Singh, Madhu S. B, Shailasree Sekhar, Gopenath TS, & Dr. Sushma BV. (2020). In Vitro Antioxidant, Anti-Inflammatory And Anti-Microbial Activity of Carica Papaya Seeds. Global Journal of Medical Research, 20(B2), 19–38. Retrieved from https://medicalresearchjournal.org/index.php/GJMR/article/view/1962

In Vitro Antioxidant, Anti-Inflammatory And Anti-Microbial Activity of Carica Papaya Seeds

Published

2020-01-15