The uncontrolled expansion of the novel coronavirus has stirred panic and unwelcoming sentiment and economic loss towards the world. The full spectrum of COVID-19 ranges from mild to severe respiratory illness with severe progressive pneumonia, multiorgan failure, and death. COVID-19 highly transmitted from person to person, thus need to the isolation of patients and maintain the quarantine. Lots of sought gain insights for vaccine design against SARS-CoV-2 (Severe Acute Respiratory Syndrome-Coronavirus-2) by considering the genetic similarities to SARS-CoV. This review article discusses the official updates on coronavirus, symptoms, transmission, diagnosis, reviews on pathogenesis, structure, treatment policy and our opinions on the use of drugs for the treatment of COVID-19 infection.