Abstract

Introduction: The present research featured extracts of Hedysarum alpinum L. and Garcinia mangostana L. The extract of Hedysarum alpinum L. proved to have a more pronounced effect on the dopamine-induced changes in animal behavior in an active avoidance conditioning model as compared with such popular antipsychotic drug as haloperidol. Methodology: The antipsychotic effect was evaluated based on active avoidance conditioning model in a two-compartment shuttle chamber. The anti-anxiety effect was evaluated in terms of passive avoidance conditioning. The side depressive effect of the extracts was evaluated based on the behavior of the animals during the Open Field test.

How to Cite
YU.S., KULPIN P.V. , SUSLOV N.I., DENISOVA S.V, TRETYAK V.M., MERKURYEVA A.G., BEREGOVYKH G.V. , BARKIN I.M., LYAMIN E .S., Fedorova. A Study of the Psychotropic Activity of Extracts of Hedysarum Alpinum L. and Garcinia Mangostana L.. Global Journal of Medical Research, [S.l.], may 2020. ISSN 2249-4618. Available at: <https://medicalresearchjournal.org/index.php/GJMR/article/view/2063>. Date accessed: 27 sep. 2020.


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