Eminence Grise of the Genome: Long Non-Coding Ribonucleic Acids in oral Squamous Cell Carcinomas
Keywords:
oral squamous cell carcinoma, potentially malignant disorders, non-coding RNAs, long non-coding RNAs, competing endogenous RNA
Abstract
Non-coding ribonucleic acids ncRNAs are a class of RNA molecules that are transcribed but not translated into proteins but they affect various cellular processes Around 60 of genes in humans do not code proteins but regulate target gene expression Presently a lot of research is carried out on ncRNA involvement in oral squamous cell carcinoma OSCC and its precursor lesions termed as oral potentially malignant disorders OPMDs They are broadly classified as small ncRNAs sncRNA and long ncRNAs lncRNA sncRNAs are extensively studied whereas the divulgence of lncRNAs in OSCCs needs more revelation hence reviewed in the present article LncRNAs have a base pair length of more than 200 can form complex structures and influence the gene expression in a multifaceted pattern that attracts interest
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2020-03-15
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